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anti-Human FLT3 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended FLT3 Antibody (supplied by: Log in to see )

Antigen
Fms-Related tyrosine Kinase 3 (FLT3) Antibodies
  • B230315G04
  • CD135
  • FLK-2
  • Flk-2
  • FLK2
  • Flk2
  • Flt-3
  • FLT3
  • Ly72
  • STK1
  • wmfl
Epitope
C-Term
43
29
27
20
19
15
14
13
10
5
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
277
129
40
1
1
1
Host
Rabbit
244
59
20
1
Clonality
Polyclonal
Conjugate
This FLT3 antibody is un-conjugated
20
18
16
13
10
6
4
4
4
4
4
4
4
4
4
4
2
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
163
121
76
46
46
44
20
16
10
3
2
2
2
1
1
Supplier
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Catalog No. ABIN359869
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.3448582 ABIN359868 EIA IHC (p) WB Rabbit Ig N-Term Log in to see Polyclonal 5
0.3448582 ABIN498839 IHC (p) Rabbit pTyr591 Log in to see Polyclonal
0.3448582 ABIN498928 IHC (p) Rabbit Log in to see Polyclonal
0.3448582 ABIN213538 IHC (p) ELISA Rabbit Internal Region Log in to see Polyclonal
0.3448582 ABIN684868 IF (p) IHC (p) WB Rabbit IgG pTyr842 Log in to see Polyclonal
0.000896905 ABIN391981 FACS IHC (p) WB Rabbit Ig AA 33-64, N-Term Log in to see Polyclonal 4
0.000896905 ABIN391982 IHC (p) WB Rabbit Ig AA 951-982, C-Term Log in to see Polyclonal 4
0.000896905 ABIN302527 IHC (p) Rabbit Internal Region Log in to see Polyclonal
0.000896905 ABIN1048599 IHC (p) Rabbit N-Term Log in to see Polyclonal
0.000896905 ABIN1048600 IHC (p) Rabbit Log in to see Polyclonal
0.000896905 ABIN625859 FACS IHC (p) Mouse IgG1 Log in to see BV10A4H2
0.000896905 ABIN1804216 IHC (p) WB Rabbit Internal Region Log in to see Polyclonal
0.000896905 ABIN616764 FACS IHC (p) Mouse IgG1 Log in to see BV10A4H2
0.000896905 ABIN1823489 IHC (p) ELISA WB Mouse IgG1 AA 930-991 Log in to see 7B7C3
0.000896905 ABIN684853 IF (p) IHC (p) WB Rabbit IgG pTyr589, pTyr591 Log in to see Polyclonal
0.000896905 ABIN2618347 IHC (p) Rabbit IgG AA 523-784 Log in to see Polyclonal
0.000896905 ABIN1868002 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 334-543 Log in to see Polyclonal
0.000896905 ABIN1724083 FACS IHC (p) Mouse IgG1 Log in to see BV10A4H2
0.000896905 ABIN1734379 IHC (p) ELISA WB Rabbit IgG C-Term Log in to see Polyclonal
0.000896905 ABIN1734378 IHC (p) Rabbit IgG C-Term Log in to see Polyclonal

Similar anti-FLT3 Antibodies

Application / Reactivity Human
ELISA 106 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Flow Cytometry (FACS) 61 Antibodies
Immunocytochemistry (ICC) 3 Antibodies
Immunofluorescence (IF) 15 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 46 Antibodies
Immunohistochemistry (IHC) 45 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 47 Antibodies
Immunoprecipitation (IP) 14 Antibodies
Western Blotting (WB) 136 Antibodies

General

Antigen Fms-Related tyrosine Kinase 3 (FLT3) Antibodies
Epitope C-Term
(43), (29), (27), (20), (19), (15), (14), (13), (10), (5), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(277), (129), (40), (1), (1), (1)
Host Rabbit
(244), (59), (20), (1)
Clonality
Polyclonal
Conjugate This FLT3 antibody is un-conjugated
(20), (18), (16), (13), (10), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (2), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(163), (121), (76), (46), (46), (44), (20), (16), (10), (3), (2), (2), (2), (1), (1)
Pubmed 5 references available
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Product Details anti-FLT3 Antibody

Target Details FLT3 Application Details Handling References for anti-FLT3 Antibody (ABIN359869) Images
Specificity This antibody reacts to FLT3 (CD135).
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human FLT3.
Isotype Ig

Target Details FLT3

Product Details anti-FLT3 Antibody Application Details Handling References for anti-FLT3 Antibody (ABIN359869) Images back to top
Antigen
Alternative Name CD135 / FLT3 (FLT3 Antibody Abstract)
Background Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).Synonyms: FL cytokine receptor, STK1, Stem cell tyrosine kinase 1, Tyrosine-protein kinase receptor FLT3
Gene ID 2322, 9606
UniProt P36888
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways RTK Signaling

Application Details

Product Details anti-FLT3 Antibody Target Details FLT3 Handling References for anti-FLT3 Antibody (ABIN359869) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50- 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-FLT3 Antibody Target Details FLT3 Application Details References for anti-FLT3 Antibody (ABIN359869) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-FLT3 Antibody (ABIN359869)

Product Details anti-FLT3 Antibody Target Details FLT3 Application Details Handling Images back to top
Background publications

Seidlits, Reza, Briand, Sereno: "Voluntary spatial attention has different effects on voluntary and reflexive saccades." in: TheScientificWorldJournal, Vol. 3, pp. 881-902, 2003

Minami, Yamamoto, Kiyoi, Ueda, Saito, Naoe: "Different antiapoptotic pathways between wild-type and mutated FLT3: insights into therapeutic targets in leukemia." in: Blood, Vol. 102, Issue 8, pp. 2969-75, 2003

Zwaan, Meshinchi, Radich, Veerman, Huismans, Munske, Podleschny, Hählen, Pieters, Zimmermann, Reinhardt, Harbott, Creutzig, Kaspers, Griesinger: "FLT3 internal tandem duplication in 234 children with acute myeloid leukemia: prognostic significance and relation to cellular drug resistance." in: Blood, Vol. 102, Issue 7, pp. 2387-94, 2003

Galimberti, Rossi, Palumbo, Morabito, Guerrini, Vincelli, Fazzi, Santini, Petrini: "FLT3 mutations do not influence MDR-1 gene expression in acute myeloid leukemia." in: Anticancer research, Vol. 23, Issue 4, pp. 3419-26, 2003

Kottaridis, Gale, Linch: "Prognostic implications of the presence of FLT3 mutations in patients with acute myeloid leukemia." in: Leukemia & lymphoma, Vol. 44, Issue 6, pp. 905-13, 2003

Images

Product Details anti-FLT3 Antibody Target Details FLT3 Application Details Handling References for anti-FLT3 Antibody (ABIN359869) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-FLT3 antibody (Fms-Related tyrosine Kinase 3) (C-Term) (ABIN359869) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Western Blotting (WB) image for anti-FLT3 antibody (Fms-Related tyrosine Kinase 3) (C-Term) (ABIN359869) Western blot analysis of anti-FLT3 Pab in 293 cell lysate. FLT3 (arrow) was detected ...