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anti-Mouse (Murine) FLT3 antibody for Immunocytochemistry

Recommended FLT3 Antibody (supplied by: Log in to see )

Antigen
Fms-Related tyrosine Kinase 3 (FLT3) Antibodies
  • B230315G04
  • CD135
  • FLK-2
  • Flk-2
  • FLK2
  • Flk2
  • Flt-3
  • FLT3
  • Ly72
  • STK1
  • wmfl
Reactivity
Mouse (Murine)
278
128
40
1
1
1
Host
Rat
245
59
19
1
Clonality
Monoclonal
Conjugate
This FLT3 antibody is conjugated to APC
20
18
16
12
10
6
4
4
4
4
4
4
4
4
4
4
2
1
1
Application
Blocking Reagent (BR), Immunocytochemistry (ICC), Flow Cytometry (FACS), Western Blotting (WB)
163
121
75
46
46
45
20
16
9
4
2
2
1
1
1
Supplier
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Catalog No. ABIN2658479
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0010161072 ABIN211924 ICC IP WB Rabbit IgG AA 786-1000 Log in to see Polyclonal
0.0010161072 ABIN2658480 BR ICC FACS WB APC Rat IgG2a kappa Log in to see A2F10 7
0.0010161072 ABIN1112889 ICC WB Rabbit IgG Log in to see Polyclonal
0.0010161072 ABIN1854896 ICC IF WB Rabbit IgG N-Term Log in to see Polyclonal
0.0010161072 ABIN1576546 ICC WB Rabbit IgG Log in to see Polyclonal
0.0010161072 ABIN1576547 ICC WB Biotin Rabbit IgG Log in to see Polyclonal

Top referenced anti-FLT3 antibody for Immunocytochemistry

Similar anti-FLT3 Antibodies

Application / Reactivity Mouse (Murine)
Blocking Reagent (BR) 2 Antibodies
ELISA 44 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 16 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 7 Antibodies
Immunofluorescence (IF) 5 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 35 Antibodies
Immunohistochemistry (IHC) 11 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 12 Antibodies
Immunoprecipitation (IP) 6 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies
Western Blotting (WB) 76 Antibodies

General

Antigen Fms-Related tyrosine Kinase 3 (FLT3) Antibodies
Reactivity Mouse (Murine)
(278), (128), (40), (1), (1), (1)
Host Rat
(245), (59), (19), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This FLT3 antibody is conjugated to APC
(20), (18), (16), (12), (10), (6), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (2), (1), (1)
Application Blocking Reagent (BR), Immunocytochemistry (ICC), Flow Cytometry (FACS), Western Blotting (WB)
(163), (121), (75), (46), (46), (45), (20), (16), (9), (4), (2), (2), (1), (1), (1)
Pubmed 7 references available
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Product Details anti-FLT3 Antibody

Target Details FLT3 Application Details Handling References for anti-FLT3 Antibody (ABIN2658479) Images
Purification The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
Clone A2F10
Isotype IgG2a kappa

Target Details FLT3

Product Details anti-FLT3 Antibody Application Details Handling References for anti-FLT3 Antibody (ABIN2658479) Images back to top
Antigen
Alternative Name CD135 (FLT3 Antibody Abstract)
Background CD135, also known as Flk-2, Flt3, and Ly-72, is a type III tyrosine kinase receptor. It is expressed on early B lymphoid lineage cells in bone marrow, on primitive myeloid progenitors within the BM CD34+ cell population. Ligation of Flk-2 with Flt3 ligand regulates the growth of hematopoietic stem cells and promotes the survival of primitive hematopoietic progenitor cells with myeloid as well as B lymphoid potential. It was reported that the receptor tyrosine kinase Flt3 is required for dendritic cell development. Combined signaling through interleukin-7 receptors and Flt3 selectively promotes B-cell commitment and differentiation from uncommitted murine bone marrow progenitor cells.
Research Area CD Antigens
Pathways RTK Signaling

Application Details

Product Details anti-FLT3 Antibody Target Details FLT3 Handling References for anti-FLT3 Antibody (ABIN2658479) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-FLT3 Antibody Target Details FLT3 Application Details References for anti-FLT3 Antibody (ABIN2658479) Images back to top
Concentration 0.2 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-FLT3 Antibody (ABIN2658479)

Product Details anti-FLT3 Antibody Target Details FLT3 Application Details Handling Images back to top
Background publications

Auffray, Fogg, Narni-Mancinelli, Senechal, Trouillet, Saederup, Leemput, Bigot, Campisi, Abitbol, Molina, Charo, Hume, Cumano, Lauvau, Geissmann: "CX3CR1+ CD115+ CD135+ common macrophage/DC precursors and the role of CX3CR1 in their response to inflammation." in: The Journal of experimental medicine, Vol. 206, Issue 3, pp. 595-606, 2009

Waskow, Liu, Darrasse-Jèze, Guermonprez, Ginhoux, Merad, Shengelia, Yao, Nussenzweig: "The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues." in: Nature immunology, Vol. 9, Issue 6, pp. 676-83, 2008

Sergejeva, Johansson, Malmhäll, Lötvall: "Allergen exposure-induced differences in CD34+ cell phenotype: relationship to eosinophilopoietic responses in different compartments." in: Blood, Vol. 103, Issue 4, pp. 1270-7, 2004

Ogawa, Sugawara, Kunisada, Sudo, Hayashi, Nishikawa, Kodama, Nishikawa: "Flt3/Flk-2 and c-Kit are not essential for the proliferation of B lymphoid progenitor cells in the bone marrow of the adult mouse." in: Experimental hematology, Vol. 26, Issue 6, pp. 478-88, 1998

Veiby, Jacobsen, Cui, Lyman, Jacobsen: "The flt3 ligand promotes the survival of primitive hemopoietic progenitor cells with myeloid as well as B lymphoid potential. Suppression of apoptosis and counteraction by TNF-alpha and TGF-beta." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 157, Issue 7, pp. 2953-60, 1996

Veiby, Lyman, Jacobsen: "Combined signaling through interleukin-7 receptors and flt3 but not c-kit potently and selectively promotes B-cell commitment and differentiation from uncommitted murine bone marrow progenitor cells." in: Blood, Vol. 88, Issue 4, pp. 1256-65, 1996

Matthews, Jordan, Wiegand, Pardoll, Lemischka: "A receptor tyrosine kinase specific to hematopoietic stem and progenitor cell-enriched populations." in: Cell, Vol. 65, Issue 7, pp. 1143-52, 1991

Images

Product Details anti-FLT3 Antibody Target Details FLT3 Application Details Handling References for anti-FLT3 Antibody (ABIN2658479) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-FLT3 antibody (Fms-Related tyrosine Kinase 3)  (APC) (ABIN2658479) anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (APC)
Flow Cytometry (FACS) image for anti-FLT3 antibody (Fms-Related tyrosine Kinase 3)  (APC) (ABIN2658479) anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (APC) (Image 2)