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anti-Mouse (Murine) FLT4 antibody for Flow Cytometry

Recommended FLT4 Antibody (supplied by: Log in to see )

Antigen
Fms-Related Tyrosine Kinase 4 (FLT4) Antibodies
  • 6130401C07
  • AI323512
  • cb1059
  • Chy
  • Flk-1
  • Flk1
  • Flt-4
  • FLT41
  • Krd-1
  • LMPH1A
  • Ly73
  • PCL
  • sVEGFR-2
  • VEGFR-2
  • VEGFR-3
  • VEGFR2
  • Vegfr3
  • VEGFR3
Reactivity
Mouse (Murine)
159
74
30
1
1
Host
Rat
118
62
16
4
1
Clonality
Monoclonal
Conjugate
This FLT4 antibody is un-conjugated
13
7
6
6
4
2
2
2
2
2
2
2
2
2
2
Application
Flow Cytometry (FACS)
115
83
55
31
26
22
20
12
9
9
4
3
3
2
1
Supplier
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Catalog No. ABIN2665901
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0010455067 ABIN957559 IHC (fro) FACS IHC (p) IP WB Rat IgG2a, kappa Log in to see AFL4
0.0010455067 ABIN2665457 FACS Rat IgG2a kappa Log in to see AFL4 9
0.0010455067 ABIN1830462 FACS PE Goat IgG Extracellular Domain Log in to see Polyclonal
0.0010455067 ABIN598380 FACS APC Goat IgG Log in to see Polyclonal
0.0010455067 ABIN1724128 IHC (fro) FACS IHC (p) IP WB Rat IgG2a kappa Log in to see AFL4
0.0010455067 ABIN2665900 FACS Rat IgG2a kappa Log in to see AFL4 8
0.0010455067 ABIN2665456 FACS Rat IgG2a kappa Log in to see AFL4 9
0.0010455067 ABIN476713 FACS Biotin Rat IgG2a, kappa Log in to see AFL4
0.0010455067 ABIN2471709 FACS IP IHC WB Mouse IgG2a kappa Log in to see AFL4
0.0010455067 ABIN2385252 FACS PE Goat IgG Log in to see Polyclonal
0.0010455067 ABIN2384631 FACS APC Goat IgG Log in to see Polyclonal
0.0010455067 ABIN281068 Func FACS IHC (fro) IP WB Rat IgG2a kappa Log in to see AFL4
0.0010455067 ABIN279928 FACS Biotin Rat IgG2a kappa Log in to see AFL4
0.0010455067 ABIN2154594 FACS Biotin Rat IgG2a kappa Log in to see AFL4
0.0010455067 ABIN2154588 Func FACS Rat IgG2a kappa Log in to see AFL4
0.0010455067 ABIN282491 Func FACS Rat IgG2a Log in to see AFL4

Top referenced anti-FLT4 antibody for Flow Cytometry

Similar anti-FLT4 Antibodies

Application / Reactivity Mouse (Murine)
ELISA 18 Antibodies
Flow Cytometry (FACS) 17 Antibodies
Functional Studies (Func) 3 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 2 Antibodies
Immunofluorescence (IF) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies
Immunohistochemistry (IHC) 13 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 7 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 15 Antibodies
Immunoprecipitation (IP) 7 Antibodies
Western Blotting (WB) 34 Antibodies

General

Antigen Fms-Related Tyrosine Kinase 4 (FLT4) Antibodies
Reactivity Mouse (Murine)
(159), (74), (30), (1), (1)
Host Rat
(118), (62), (16), (4), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This FLT4 antibody is un-conjugated
(13), (7), (6), (6), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Flow Cytometry (FACS)
(115), (83), (55), (31), (26), (22), (20), (12), (9), (9), (4), (3), (3), (2), (1)
Pubmed 8 references available
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Product Details anti-FLT4 Antibody

Target Details FLT4 Application Details Handling References for anti-FLT4 Antibody (ABIN2665901) Images
Brand LEAF™
Purification The LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Sterility 0.2 μm filtered
Endotoxin Level

Endotoxin level is <0.1 EU/μg of the protein (<0.01 ng/μg of the protein) as determined by the LAL test.

Clone AFL4
Isotype IgG2a kappa

Target Details FLT4

Product Details anti-FLT4 Antibody Application Details Handling References for anti-FLT4 Antibody (ABIN2665901) Images back to top
Antigen
Alternative Name VEGFR-3 (FLT4 Antibody Abstract)
Background VEGFR-3, also known as FLT4, is a member of the Tyr protein kinase family. The extracellular portion of VEGFR-3 contains 7 immunoglobulin (Ig)-like domains and the cytoplasmic portion contains a protein kinase domain. FLT4 regulates angiogenesis and lymphangiogenesis, its ligands are VEGF-C and D and its binding is mediated by the 2nd and 3rd Ig-like domains of FLT4. During fetal development VEGFR-3 is expressed on endothelial cells, however, in the adult mice, the vascular endothelial cells lose VEGFR-3 expression, but the lymphatic endothelium expresses it constitutively. In addition, VEGFR-3 expression can be induced in tumors with active angiogenesis.
Pathways RTK Signaling

Application Details

Product Details anti-FLT4 Antibody Target Details FLT4 Handling References for anti-FLT4 Antibody (ABIN2665901) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-FLT4 Antibody Target Details FLT4 Application Details References for anti-FLT4 Antibody (ABIN2665901) Images back to top
Concentration 1.0 mg/mL
Preservative Azide free
Handling Advice This LEAF™ solution contains no preservative, handle under aseptic conditions
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-FLT4 Antibody (ABIN2665901)

Product Details anti-FLT4 Antibody Target Details FLT4 Application Details Handling Images back to top
Background publications

Uhrin, Zaujec, Breuss, Olcaydu, Chrenek, Stockinger, Fuertbauer, Moser, Haiko, Fässler, Alitalo, Binder, Kerjaschki: "Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation." in: Blood, Vol. 115, Issue 19, pp. 3997-4005, 2010

Wang, Nakayama, Pitulescu, Schmidt, Bochenek, Sakakibara, Adams, Davy, Deutsch, Lüthi, Barberis, Benjamin, Mäkinen, Nobes, Adams: "Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis." in: Nature, Vol. 465, Issue 7297, pp. 483-6, 2010

Jakobsson, Bentley, Gerhardt: "VEGFRs and Notch: a dynamic collaboration in vascular patterning." in: Biochemical Society transactions, Vol. 37, Issue Pt 6, pp. 1233-6, 2009

Huang, Chen: "Tumor vasculature and microenvironment normalization: a possible mechanism of antiangiogenesis therapy." in: Cancer biotherapy & radiopharmaceuticals, Vol. 23, Issue 5, pp. 661-7, 2008

Tammela, Zarkada, Wallgard, Murtomäki, Suchting, Wirzenius, Waltari, Hellström, Schomber, Peltonen, Freitas, Duarte, Isoniemi, Laakkonen, Christofori, Ylä-Herttuala, Shibuya, Pytowski, Eichmann et al.: "Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. ..." in: Nature, Vol. 454, Issue 7204, pp. 656-60, 2008

Zhang, Fang: "Molecular staging of gastric cancer." in: Journal of gastroenterology and hepatology, Vol. 23, Issue 6, pp. 856-60, 2008

Shimizu, Kubo, Yamaguchi, Kawashima, Ueda, Matsuo, Awane, Shimahara, Takabayashi, Yamaoka, Satoh: "Suppression of VEGFR-3 signaling inhibits lymph node metastasis in gastric cancer." in: Cancer science, Vol. 95, Issue 4, pp. 328-33, 2004

Matsumura, Hirashima, Ogawa, Kubo, Hisatsune, Kondo, Nishikawa, Chiba, Nishikawa: "Modulation of VEGFR-2-mediated endothelial-cell activity by VEGF-C/VEGFR-3." in: Blood, Vol. 101, Issue 4, pp. 1367-74, 2003

Images

Product Details anti-FLT4 Antibody Target Details FLT4 Application Details Handling References for anti-FLT4 Antibody (ABIN2665901) back to top
Supplier Images
Immunofluorescence (IF) image for anti-FLT4 antibody (Fms-Related Tyrosine Kinase 4) (ABIN2665901) anti-Fms-Related Tyrosine Kinase 4 (FLT4) antibody
Immunofluorescence (IF) image for anti-FLT4 antibody (Fms-Related Tyrosine Kinase 4) (ABIN2665901) anti-Fms-Related Tyrosine Kinase 4 (FLT4) antibody (Image 2)