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anti-Rat (Rattus) FLT4 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended FLT4 Antibody (supplied by: Log in to see )

Antigen
Fms-Related Tyrosine Kinase 4 (FLT4) Antibodies
  • 6130401C07
  • AI323512
  • cb1059
  • Chy
  • Flk-1
  • Flk1
  • Flt-4
  • FLT41
  • Krd-1
  • LMPH1A
  • Ly73
  • PCL
  • sVEGFR-2
  • VEGFR-2
  • VEGFR-3
  • VEGFR2
  • Vegfr3
  • VEGFR3
Epitope
AA 910-960
35
14
13
13
12
9
9
6
6
3
3
3
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
158
75
30
2
1
Host
Rabbit
119
61
17
4
1
Clonality
Polyclonal
Conjugate
This FLT4 antibody is un-conjugated
13
7
6
6
4
2
2
2
2
2
2
2
2
2
2
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
113
83
55
30
27
21
20
12
10
9
4
3
3
2
1
Supplier
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Catalog No. ABIN678578
$ 269.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089488085 ABIN266201 IHC (p) IHC Rabbit IgG C-Term Log in to see Polyclonal
0.00089488085 ABIN737406 IF (p) IHC (p) WB Rabbit IgG AA 920-970 Log in to see Polyclonal 1
0.00089488085 ABIN373447 IHC (p) WB Rabbit C-Term Log in to see Polyclonal
0.00089488085 ABIN678580 IHC (p) WB Biotin Rabbit IgG AA 910-960 Log in to see Polyclonal
0.00089488085 ABIN678587 IHC (p) WB HRP Rabbit IgG AA 910-960 Log in to see Polyclonal
0.00089488085 ABIN737408 IHC (p) WB Biotin Rabbit IgG AA 920-970 Log in to see Polyclonal
0.00089488085 ABIN737415 IHC (p) WB HRP Rabbit IgG AA 920-970 Log in to see Polyclonal
0.00089488085 ABIN1734382 IHC (p) IP WB Rabbit IgG C-Term Log in to see Polyclonal

Top referenced anti-FLT4 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-FLT4 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 2 Antibodies 19 Antibodies
Immunofluorescence (IF) 1 Antibodies 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies 22 Antibodies
Immunohistochemistry (IHC) 2 Antibodies 14 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 9 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Western Blotting (WB) 9 Antibodies
Flow Cytometry (FACS) 17 Antibodies
Functional Studies (Func) 3 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 2 Antibodies

General

Antigen Fms-Related Tyrosine Kinase 4 (FLT4) Antibodies
Epitope AA 910-960
(35), (14), (13), (13), (12), (9), (9), (6), (6), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(158), (75), (30), (2), (1)
Host Rabbit
(119), (61), (17), (4), (1)
Clonality
Polyclonal
Conjugate This FLT4 antibody is un-conjugated
(13), (7), (6), (6), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(113), (83), (55), (30), (27), (21), (20), (12), (10), (9), (4), (3), (3), (2), (1)
Pubmed 2 references available
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Product Details anti-FLT4 Antibody

Target Details FLT4 Application Details Handling References for anti-FLT4 Antibody (ABIN678578) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human VEGFR-3
Isotype IgG

Target Details FLT4

Product Details anti-FLT4 Antibody Application Details Handling References for anti-FLT4 Antibody (ABIN678578) Images back to top
Antigen
Alternative Name Vegfr3 (FLT4 Antibody Abstract)
Background

Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFC and VEGFD, and plays an essential role in adult lymphangiogenesis and in the development of the vascular network and the cardiovascular system during embryonic development. Promotes proliferation, survival and migration of endothelial cells, and regulates angiogenic sprouting. Signaling by activated FLT4 leads to enhanced production of VEGFC, and to a lesser degree VEGFA, thereby creating a positive feedback loop that enhances FLT4 signaling. Modulates KDR signaling by forming heterodimers. The secreted isoform 3 may function as a decoy receptor for VEGFC and/or VEGFD and play an important role as a negative regulator of VEGFC-mediated lymphangiogenesis and angiogenesis. Binding of vascular growth factors to isoform 1 or isoform 2 leads to the activation of several signaling cascades, isoform 2 seems to be less efficient in signal transduction, because it has a truncated C-terminus and therefore lacks several phosphorylation sites. Mediates activation of the MAPK1/ERK2, MAPK3/ERK1 signaling pathway, of MAPK8 and the JUN signaling pathway, and of the AKT1 signaling pathway. Phosphorylates SHC1. Mediates phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase. Promotes phosphorylation of MAPK8 at 'Thr-183' and 'Tyr-185', and of AKT1 at 'Ser-473'.

Subcellular location: Cytoplasm


Synonyms: PCL, FLT41, LMPH1A, VEGFR3, Vascular endothelial growth factor receptor 3, VEGFR-3, Fms-like tyrosine kinase 4, FLT-4, Tyrosine-protein kinase receptor FLT4, FLT4
Gene ID 2324
UniProt P35916
Pathways RTK Signaling

Application Details

Product Details anti-FLT4 Antibody Target Details FLT4 Handling References for anti-FLT4 Antibody (ABIN678578) Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-FLT4 Antibody Target Details FLT4 Application Details References for anti-FLT4 Antibody (ABIN678578) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

References for anti-FLT4 Antibody (ABIN678578)

Product Details anti-FLT4 Antibody Target Details FLT4 Application Details Handling Images back to top
Product cited in:

Zhuo, Jia, Song, Lu, Ding, Wang, Song, Fu, Luo: "The CXCL12-CXCR4 chemokine pathway: a novel axis regulates lymphangiogenesis." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 18, Issue 19, pp. 5387-98, 2012

Wang, Zhou, Lin, Wang, Lin, Li: "RhGH attenuates ischemia injury of intrahepatic bile ducts relating to liver transplantation." in: The Journal of surgical research, Vol. 171, Issue 1, pp. 300-10, 2011

Images

Product Details anti-FLT4 Antibody Target Details FLT4 Application Details Handling References for anti-FLT4 Antibody (ABIN678578) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-FLT4 antibody (Fms-Related Tyrosine Kinase 4) (AA 910-960) (ABIN678578) Formalin-fixed and paraffin embedded human gastric cancer labeled with Anti-VEGFR3 Po...
Immunohistochemistry (IHC) image for anti-FLT4 antibody (Fms-Related Tyrosine Kinase 4) (AA 910-960) (ABIN678578) Formalin-fixed and paraffin embedded human gastric cancer labeled with Anti-VEGFR3 P...