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|Application / Reactivity||Human|
|Blocking Antibody (Inhibition)||1 Antibodies|
|Blocking Reagent (BR)||1 Antibodies|
|Cellular Assay (CA)||1 Antibodies|
|Dot Blot (DB)||1 Antibodies|
|Enzyme Immunoassay (EIA)||7 Antibodies|
|Flow Cytometry (FACS)||42 Antibodies|
|Functional Studies (Func)||4 Antibodies|
|Immunoassay (IA)||3 Antibodies|
|Immunochromatography (IC)||3 Antibodies|
|Immunocytochemistry (ICC)||15 Antibodies|
|Immunofluorescence (IF)||50 Antibodies|
|Immunofluorescence (Paraffin-embedded Sections) (IF (p))||2 Antibodies|
|Immunohistochemistry (IHC)||103 Antibodies|
|Immunohistochemistry (Formalin-fixed Sections) (IHC (f))||1 Antibodies|
|Immunohistochemistry (Frozen Sections) (IHC (fro))||14 Antibodies|
|Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))||63 Antibodies|
|Immunoprecipitation (IP)||12 Antibodies|
|Antigen||Lectin, Galactoside-Binding, Soluble, 3 (LGALS3) Antibodies|
|Epitope||C-Term, AA 170-199 Alternatives|
|Conjugate||This Galectin 3 antibody is un-conjugated Alternatives|
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Western Blotting (WB)
|5 references available|
|Supplier||Log in to see|
Product Details anti-Galectin 3 AntibodyTarget Details Galectin 3 Application Details Handling References for anti-Galectin 3 Antibody (ABIN952435) Images
|Specificity||This antibody recognizes Human Galectin-3 (C-term).|
|Purification||Protein A column, followed by peptide affinity purification|
|Immunogen||conjugated synthetic peptide between 170-199 amino acids from the C-terminal region of human Galectin-3 Genename: LGALS3|
Target Details Galectin 3Product Details anti-Galectin 3 Antibody Application Details Handling References for anti-Galectin 3 Antibody (ABIN952435) Images back to top
|Alternative Name||Galectin-3 (LGALS3 Antibody Abstract)|
|Background||This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.Synonyms: 35 kDa lectin, CBP35, Carbohydrate-binding protein 35, GAL3, GALBP, Galactose-specific lectin 3, IgE-binding protein, L-31, L-34 galactoside-binding lectin, Laminin-binding protein, Lectin L-29, Lgals3, Mac-2|
|Molecular Weight||26152 Da|
Application DetailsProduct Details anti-Galectin 3 Antibody Target Details Galectin 3 Handling References for anti-Galectin 3 Antibody (ABIN952435) Images back to top
|Application Notes||Optimal working dilution should be determined by the investigator.|
|Restrictions||For Research Use only|
HandlingProduct Details anti-Galectin 3 Antibody Target Details Galectin 3 Application Details References for anti-Galectin 3 Antibody (ABIN952435) Images back to top
|Buffer||PBS containing 0.09 % (W/V) Sodium Azide as preservative|
|Precaution of Use||This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Handling Advice||Avoid repeated freezing and thawing.|
|Storage||4 °C/-20 °C|
|Storage Comment||Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.|
References for anti-Galectin 3 Antibody (ABIN952435)Product Details anti-Galectin 3 Antibody Target Details Galectin 3 Application Details Handling Images back to top
Salomonsson, Carlsson, Osla et al.: "Mutational tuning of galectin-3 specificity and biological function." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 35079-91, 2010 (PubMed).
Debierre-Grockiego, Niehus, Coddeville et al.: "Binding of Toxoplasma gondii glycosylphosphatidylinositols to galectin-3 is required for their recognition by macrophages." in: The Journal of biological chemistry, Vol. 285, Issue 43, pp. 32744-50, 2010 (PubMed).
Markowska, Liu, Panjwani: "Galectin-3 is an important mediator of VEGF- and bFGF-mediated angiogenic response." in: The Journal of experimental medicine, Vol. 207, Issue 9, pp. 1981-93, 2010 (PubMed).
Zhou, Afjehi-Sadat, Asress et al.: "Galectin-3 is a candidate biomarker for amyotrophic lateral sclerosis: discovery by a proteomics approach." in: Journal of proteome research, Vol. 9, Issue 10, pp. 5133-41, 2010 (PubMed).
Mazurek, Conklin, Byrd et al.: "Phosphorylation of the beta-galactoside-binding protein galectin-3 modulates binding to its ligands." in: The Journal of biological chemistry, Vol. 275, Issue 46, pp. 36311-5, 2000 (PubMed).
ImagesProduct Details anti-Galectin 3 Antibody Target Details Galectin 3 Application Details Handling References for anti-Galectin 3 Antibody (ABIN952435) back to top