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anti-Cow (Bovine) GRB2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended GRB2 Antibody (supplied by: Log in to see )

Antigen
Growth Factor Receptor-Bound Protein 2 (GRB2) Antibodies
  • AA408164
  • ASH
  • Ash
  • EGFRBP-GRB2
  • GRB2
  • grb2
  • Grb3-3
  • MST084
  • MSTP084
  • NCKAP2
  • wu:fb18e12
  • wu:fb34e06
  • zgc:73077
Epitope
AA 198-217, C-Term
34
18
15
7
6
6
5
3
3
3
3
2
2
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
148
41
41
9
8
3
3
2
2
2
2
1
1
Host
Rabbit
98
29
22
2
Clonality
Polyclonal
Conjugate
This GRB2 antibody is un-conjugated
5
4
3
3
3
3
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
129
65
53
29
9
8
5
3
3
2
1
Supplier
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Catalog No. ABIN615588
$ 500.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089488085 ABIN782889 EIA IHC (p) WB Goat C-Term Log in to see Polyclonal 1
0.00089488085 ABIN374150 EIA IHC (p) WB Goat C-Term Log in to see Polyclonal 1
0.00089488085 ABIN180592 IF IHC (p) Mouse IgG1 Log in to see 2GB04-same C1-4
0.00089488085 ABIN267213 ICC IF IHC (p) IHC Mouse IgG1 kappa Log in to see 2GB04
0.00089488085 ABIN1735236 IHC (p) ELISA WB Goat C-Term Log in to see Polyclonal

Top referenced anti-GRB2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-GRB2 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Cow (Bovine)
Western Blotting (WB) 129 Antibodies 41 Antibodies 40 Antibodies 9 Antibodies
Immunoprecipitation (IP) 9 Antibodies 3 Antibodies 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 32 Antibodies 6 Antibodies 9 Antibodies 9 Antibodies
Immunohistochemistry (IHC) 56 Antibodies 15 Antibodies 13 Antibodies 3 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 3 Antibodies

General

Antigen Growth Factor Receptor-Bound Protein 2 (GRB2) Antibodies
Epitope AA 198-217, C-Term
(34), (18), (15), (7), (6), (6), (5), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
(148), (41), (41), (9), (8), (3), (3), (2), (2), (2), (2), (1), (1)
Host Rabbit
(98), (29), (22), (2)
Clonality
Polyclonal
Conjugate This GRB2 antibody is un-conjugated
(5), (4), (3), (3), (3), (3)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(129), (65), (53), (29), (9), (8), (5), (3), (3), (2), (1)
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Product Details anti-GRB2 Antibody

Target Details GRB2 Application Details Handling Images
Specificity The polyclonal antibody recognizes Grb2, a highly conserved approximately 26 kDa adaptor protein.
Purification Immunoaffinity Chromatography
Immunogen GRB2 antibody was raised against synthetic peptide corresponding to C-terminus of human Grb2 (amino acids 198-217). .Remarks: 100% identity between man, cow, rat and mouse

Target Details GRB2

Product Details anti-GRB2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name GRB2 / ASH (GRB2 Antibody Abstract)
Background Growth factor receptor bound protein 2 (GRB2), also known as Ash protein, is a 24 kDa protein that contains a central Src homology (SH2) domain flanked by two SH3 domains. GRB2 is believed to be a regulatory subunit of signaling molecules whose activity is modulated by receptor binding. GRB2 associates with activated (tyrosine phosphorylated) EGFR and PDGFR via its SH2 domain as well as IRS1, SHC, and LNK through SH2 and SH3 domains. The SH3 domain binds to SOS, a guanine nucleotide exchange factor for Ras proteins. Endocytosis of activated EGFR requires the interaction of GRB2 with the GTP binding protein dynamin, a factor essential to the formation of endocytotic vesicle. It is ubiquitously expressed and several isoforms are produced by alternative splicing. On SDS PAGE, GRB2 has an apparent molecular weight of 28 kDa.Synonyms: Growth factor receptor-bound protein 2
Gene ID 2885
NCBI Accession NP_002077
UniProt P62993
Research Area Signaling
Pathways RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-GRB2 Antibody Target Details GRB2 Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-GRB2 Antibody Target Details GRB2 Application Details Images back to top
Buffer PBS containing 15 mM sodium azide and 0.2 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-GRB2 Antibody Target Details GRB2 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-GRB2 antibody (Growth Factor Receptor-Bound Protein 2) (AA 198-217) (ABIN615588) IHC Image for AP23211PU-N Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-GRB2 antibody (Growth Factor Receptor-Bound Protein 2) (AA 198-217) (ABIN615588) IHC Image for AP23211PU-N Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-GRB2 antibody (Growth Factor Receptor-Bound Protein 2) (AA 198-217) (ABIN615588) IHC Image for AP23211PU-N Human Colon, Myenteric Plexus: Formalin-Fixed, Paraffin-Emb...