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Browse our anti-HER2 (ERBB2) Antibodies

Full name:
anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) Antibodies (ERBB2)
On www.antibodies-online.com are 1337 V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies from 41 different suppliers available. Additionally we are shipping HER2 Proteins (82) and HER2 Kits (41) and many more products for this protein. A total of 1542 HER2 products are currently listed.
Synonyms:
c-erbB2, c-neu, CD340, Erbb-2, HER-2, HER-2/neu, HER2, mKIAA3023, MLN 19, Neu, NGL, TKR1
list all antibodies Gene Name GeneID UniProt
ERBB2 24337  
ERBB2 2064 P04626
ERBB2 13866 P70424

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All available anti-HER2 Antibodies

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Top referenced anti-HER2 Antibodies

  1. Human Monoclonal HER2 Primary Antibody for IHC (p) - ABIN1688892 : Savci-Heijink, Halfwerk, Hooijer, Horlings, Wesseling, van de Vijver: Retrospective analysis of metastatic behaviour of breast cancer subtypes. in Breast cancer research and treatment 2015 (PubMed)
    Show all 50 references for ABIN1688892

  2. Human Monoclonal HER2 Primary Antibody for IF, IHC (p) - ABIN180514 : DiGiovanna, Stern: Activation state-specific monoclonal antibody detects tyrosine phosphorylated p185neu/erbB-2 in a subset of human breast tumors overexpressing this receptor. in Cancer research 1995 (PubMed)
    Show all 11 references for ABIN180514

  3. Human Polyclonal HER2 Primary Antibody for IHC (p), WB - ABIN391947 : Ehsani, Low, Wallace, Wu: Characterization of a new allele of the human ERBB2 gene by allele-specific competition hybridization. in Genomics 1993 (PubMed)
    Show all 4 references for ABIN391947

  4. Human Polyclonal HER2 Primary Antibody for FACS, IHC (p) - ABIN391945 : Yamamoto, Ikawa, Akiyama, Semba, Nomura, Miyajima, Saito, Toyoshima: Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor. in Nature 1986 (PubMed)
    Show all 4 references for ABIN391945

  5. Human Polyclonal HER2 Primary Antibody for EIA, FACS - ABIN359840 : Coussens, Yang-Feng, Liao, Chen, Gray, McGrath, Seeburg, Libermann, Schlessinger, Francke: Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. in Science (New York, N.Y.) 1985 (PubMed)
    Show all 4 references for ABIN359840

  6. Human Polyclonal HER2 Primary Antibody for IF, ELISA - ABIN1532607 : King, Kraus, Aaronson: Amplification of a novel v-erbB-related gene in a human mammary carcinoma. in Science (New York, N.Y.) 1985 (PubMed)
    Show all 3 references for ABIN1532607

  7. Human Polyclonal HER2 Primary Antibody for IF, ELISA - ABIN1531590 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)
    Show all 3 references for ABIN1531590

  8. Human Polyclonal HER2 Primary Antibody for IHC (fro), IHC (p) - ABIN115291 : Schechter, Hung, Vaidyanathan, Weinberg, Yang-Feng, Francke, Ullrich, Coussens: The neu gene: an erbB-homologous gene distinct from and unlinked to the gene encoding the EGF receptor. in Science (New York, N.Y.) 1985 (PubMed)
    Show all 3 references for ABIN115291

More Antibodies against HER2 Interaction Partners

Human V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) interaction partners

  1. Expression and Prognostic Significance of Human Epidermal Growth Factor (show EGF Antibodies) Receptors 1, 2 and 3 in Periampullary Adenocarcinoma

  2. Tumor driven by gain-of-function HER2 H878Y mutant is highly sensitive to HER2 inhibitor.

  3. clinically sizeable 5% fraction of KRAS wild-type colorectal cancer patients was found to be ERBB2-positive according to the colorectal cancer-specific ERBB2 scoring criteria

  4. FGFR1 (show FGFR1 Antibodies) protein expression may be a biomarker of ER-positive/HER2-negative primary breast cancer with possible resistance to standard treatment, and may be a useful tool to identify more specific patients who would benefit from FGFR-1 (show FGFR1 Antibodies) targeted therapy.

  5. Assessment of the HER2 status of biopsy tissues could predict the status of the whole tumor; however, a proportion of these cases may be discordant because of intratumoral heterogeneity

  6. HER2 mutations are associated with refractory metastatic breast cancers.

  7. HER2 gene rs1136201 and rs1058808 polymorphisms and haplotype C-T-G-G may be related to osteosarcoma susceptibility in Chinese Han population

  8. measurements comprising the receptors EGFR (show EGFR Antibodies), ERBB3 (HER3 (show ERBB3 Antibodies)), and the cyclin-dependent kinase inhibitor p27 (CDKN1B (show CDKN1B Antibodies)) was found to accurately predict dependence on PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) vs. MAPK/ERK (show MAPK1 Antibodies) signaling axes in HER2+ cancers

  9. only lapatinib enhanced trastuzumab-mediated ADCC via the upregulation of HER2 expression in MPM cells, suggesting that sequential combination of lapatinib and trastuzumab may be a promising strategy for MPM treatment.

  10. Uni- and multivariate analyses included age, tumor size, grade, ER, and Her2; in multivariate analysis, MammaPrint reached near-significance (HR 3.01; p 0.08).

Mouse (Murine) V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) interaction partners

  1. Disabling of the erbB (show EGFR Antibodies) pathway followed by IFNg (show IFNG Antibodies) modifies phenotype and enhances genotoxic eradication of breast tumors.

  2. Ptk6 (show PTK6 Antibodies) promotes ERBB2-induced mammary gland tumorigenesis in the mouse.

  3. PTPN12 (show PTPN12 Antibodies)-deficient, ErbB2-dependent breast cancer cells were more resistant to anoikis and had augmented migratory and invasive properties.

  4. ErbB2 overexpression upregulates antioxidant enzymes, reduces basal levels of reactive oxygen species, and protects against doxorubicin cardiotoxicity.

  5. These results indicate that OCAM (show NCAM2 Antibodies) exerts a posttranscriptional control on the ErbB2 signalling in spinal cord stem cells. This study adds further support for considering cell adhesion molecules as regulators of the ErbB (show EGFR Antibodies) signalling

  6. the Krt6a (show KRT6A Antibodies)-positive subset of mammary epithelial cells can be induced to form cancer by ErbB2.

  7. These results suggested that DS/Cu treatment may be a promising therapy for the prevention of erbB2-positive breast cancer

  8. loss of Postn (show POSTN Antibodies) in an ErbB2/Neu/HER2 overexpression model results in apocrine-like tumors that activate an AR-dependent pathway.

  9. Inhibition of Erbb2 suppressed the increase in metalloproteinase ADAM12 (show ADAM12 Antibodies) expression in skin tumors.

  10. Data show that Muc4 (show MUC4 Antibodies) is upregulated and interacts with erbB2 in gallbladders from BK5.erbB2 mice suggesting its important role during gallbladder carcinogenesis and/or cancer growth by potentiating erbB2 signaling.

HER2 (ERBB2) Antigen Profile

Antigen Summary

This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.

Alternative names and synonyms associated with HER2 (ERBB2)

  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (ERBB2) antibody
  • v-erb-b2 avian erythroblastic leukemia viral oncogene 2 (Erbb2) antibody
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (ERBB2) antibody
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (Erbb2) antibody
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (ERBB2) antibody
  • c-erbB2 antibody
  • c-neu antibody
  • CD340 antibody
  • Erbb-2 antibody
  • HER-2 antibody
  • HER-2/neu antibody
  • HER2 antibody
  • mKIAA3023 antibody
  • MLN 19 antibody
  • Neu antibody
  • NGL antibody
  • TKR1 antibody

Protein level used designations for ERBB2

receptor tyrosine-protein kinase erbB-2 , Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog) , C-erbB-2 , NEU proto-oncogene , epidermal growth factor receptor-related protein , p185erbB2 , p185neu , proto-oncogene NEU , proto-oncogene c-ErbB-2 , v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog , c-erb B2/neu protein , herstatin , metastatic lymph node gene 19 protein , neuro/glioblastoma derived oncogene homolog , neuroblastoma/glioblastoma derived oncogene homolog , proto-oncogene Neu , tyrosine kinase-type cell surface receptor HER2 , Neu oncogene , avian erythroblastosis oncogene B 2 , c-erbB-2 , erbB-2

GENE ID SPECIES
426130 Gallus gallus
24337 Rattus norvegicus
2064 Homo sapiens
13866 Mus musculus
403883 Canis lupus familiaris
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