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Browse our anti-HER2 (ERBB2) Antibodies

Full name:
anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) Antibodies (ERBB2)
On www.antibodies-online.com are 1562 V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies from 44 different suppliers available. Additionally we are shipping HER2 Proteins (92) and HER2 Kits (44) and many more products for this protein. A total of 1780 HER2 products are currently listed.
Synonyms:
c-erbB2, c-neu, CD340, Erbb-2, HER-2, HER-2/neu, HER2, mKIAA3023, MLN 19, Neu, NGL, TKR1
list all antibodies Gene Name GeneID UniProt
ERBB2 24337  
ERBB2 2064 P04626
ERBB2 13866 P70424

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All available anti-HER2 Antibodies

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Top referenced anti-HER2 Antibodies

  1. Human Monoclonal HER2 Primary Antibody for IHC (p) - ABIN1688892 : Savci-Heijink, Halfwerk, Hooijer, Horlings, Wesseling, van de Vijver: Retrospective analysis of metastatic behaviour of breast cancer subtypes. in Breast cancer research and treatment 2015 (PubMed)
    Show all 50 references for ABIN1688892

  2. Human Monoclonal HER2 Primary Antibody for IF, IHC (p) - ABIN180514 : DiGiovanna, Stern: Activation state-specific monoclonal antibody detects tyrosine phosphorylated p185neu/erbB-2 in a subset of human breast tumors overexpressing this receptor. in Cancer research 1995 (PubMed)
    Show all 11 references for ABIN180514

  3. Human Polyclonal HER2 Primary Antibody for FACS, IHC (p) - ABIN391945 : Ehsani, Low, Wallace, Wu: Characterization of a new allele of the human ERBB2 gene by allele-specific competition hybridization. in Genomics 1993 (PubMed)
    Show all 4 references for ABIN391945

  4. Human Polyclonal HER2 Primary Antibody for EIA, FACS - ABIN359840 : Yamamoto, Ikawa, Akiyama, Semba, Nomura, Miyajima, Saito, Toyoshima: Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor. in Nature 1986 (PubMed)
    Show all 4 references for ABIN359840

  5. Human Polyclonal HER2 Primary Antibody for IHC (p), WB - ABIN391947 : Coussens, Yang-Feng, Liao, Chen, Gray, McGrath, Seeburg, Libermann, Schlessinger, Francke: Tyrosine kinase receptor with extensive homology to EGF receptor shares chromosomal location with neu oncogene. in Science (New York, N.Y.) 1985 (PubMed)
    Show all 4 references for ABIN391947

  6. Human Polyclonal HER2 Primary Antibody for IF, ELISA - ABIN1531590 : King, Kraus, Aaronson: Amplification of a novel v-erbB-related gene in a human mammary carcinoma. in Science (New York, N.Y.) 1985 (PubMed)
    Show all 3 references for ABIN1531590

  7. Human Polyclonal HER2 Primary Antibody for IHC (fro), IHC (p) - ABIN115291 : Schechter, Hung, Vaidyanathan, Weinberg, Yang-Feng, Francke, Ullrich, Coussens: The neu gene: an erbB-homologous gene distinct from and unlinked to the gene encoding the EGF receptor. in Science (New York, N.Y.) 1985 (PubMed)
    Show all 3 references for ABIN115291

More Antibodies against HER2 Interaction Partners

Human V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) interaction partners

  1. DCC (show DCC Antibodies)/18q and ERBB2/17q gene copy number variations are associated with disease-free survival in microsatellite stable colon cancer

  2. (18)F-FDG (show SMUG1 Antibodies) PET/CT may be useful for predicting the HER2 status of gastric cancer and for determining the therapeutic strategy

  3. Data suggest that HER2 expression may represent an additional aid to identify a subset of patients who are characterized by a worse prognosis and are potentially eligible for targeted therapy.

  4. JNK (show MAPK8 Antibodies) and AKT (show AKT1 Antibodies), downstream effectors of HER2, co-operatively contribute to the metastatic potential of HER2-positive gastric cancer cells.

  5. HER2 loss was identified as a mechanism of acquired resistance to trastuzumab and chemotherapy in advanced HER2-positive gastric or GEJ cancer.

  6. HER2 and NSE (show ENO2 Antibodies) serum levels were independent prognostic factors in patients with brain metastases in breast cancer. Serum HER2 and MMP-9 (show MMP9 Antibodies) appear to be associated with BM in metastatic BC patients. Their predictive value for BM still needs to be evaluated in further prospective studies.

  7. K17 (show KRT17 Antibodies) is expressed in a subset of triple-negative breast cancers, and is a marker of poor prognosis in patients with advanced stage and ER(-)/HER2(-) breast cancer.

  8. Trastuzumab acidic variants had lesser binding to oncogene (show RAB1A Antibodies) protein HER-2 (HER2) in comparison to the basic variants, and both acidic and basic variant showed no significant changes in their binding to soluble CD16a receptors.

  9. Oncogenic mutations in Her-2/neu or k-ras had no association with the severity of endometrial cancer.

  10. Findings suggest that the association of HER2 amplification with BRAF (show BRAF Antibodies)(V600E) mutation and telomere shortening may represent a marker of tumor aggressiveness, and, in refractory thyroid cancer, may warrant exploration as a site for targeted therapy.

Mouse (Murine) V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) interaction partners

  1. ErbB2 is required for neonatal cardiomyocyte proliferation. ErbB2 conditional knockout heart exhibited an upregulation of negative cell cycle regulators.

  2. Despite previous evidence suggesting that ErbB (show EGFR Antibodies) receptors can bind and activate IRSs, our findings indicate that ErbB2 does not cooperate with the IRS (show IARS Antibodies) pathway in mouse breast cancer model.

  3. It was suggested that transgenic HER-2/neu involves in initiation of malignization of mammary epithelial cells but also in acceleration of age-related hormonal and metabolic changes in turn promoting mammary carcinogenesis

  4. Study showed that suppression of STAT3 (show STAT3 Antibodies), STAT5 (show STAT5A Antibodies), and STAT6 (show STAT6 Antibodies) and overexpression of the proapoptotic factor STAT1 (show STAT1 Antibodies), which provides p53 (show TP53 Antibodies)-mediated apoptosis, are the causes for increasing the number of apoptotic neurons in physiological aging. HER-2 tyrosine kinase receptor (show KDR Antibodies) overexpression promotes neuronal survival through activation of STAT (show STAT1 Antibodies)-signaling pathway with simultaneous suppression of the proapoptotic factor STAT1 (show STAT1 Antibodies)

  5. that myocardial ErbB2 and beta-adrenergic receptors signalling are linked in a feedback loop with beta-adrenergic receptors activation leading to increased ErbB2 expression and activity

  6. Metformin inhibits breast tumor angiogenesis and suggest role of HIF-1alpha (show HIF1A Antibodies)-VEGF (show VEGFA Antibodies) signaling axis in mediating HER2-induced tumor angiogenesis.

  7. In trastuzumab-doxorubicin combination therapy in a murine model of HER2+ breast cancer.

  8. Data indicate that Sonic hedgehog (Shh (show SHH Antibodies)) stimulate branching morphogenesis (BrM (show SMARCA2 Antibodies)) and induced synthesis of mRNAs for Ptch1 (show PTCH1 Antibodies) protein, epidermal growth factor (EGF (show EGF Antibodies)) and receptors of the ErbB (show EGFR Antibodies) receptors ErbB1 (show EGFR Antibodies), ErbB2 and ErbB3 (show ERBB3 Antibodies).

  9. ErbB2 receptor tyrosine kinase (show ERBB3 Antibodies) in AECs was activated by annexin V (show ANXA5 Antibodies), and blockade reduced the fibrotic potential of annexin V (show ANXA5 Antibodies)-treated AEC-conditioned medium.

  10. Disabling of the erbB (show EGFR Antibodies) pathway followed by IFNg (show IFNG Antibodies) modifies phenotype and enhances genotoxic eradication of breast tumors.

HER2 (ERBB2) Antigen Profile

Antigen Summary

This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.

Alternative names and synonyms associated with HER2 (ERBB2)

  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (ERBB2) antibody
  • v-erb-b2 avian erythroblastic leukemia viral oncogene 2 (Erbb2) antibody
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (ERBB2) antibody
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (Erbb2) antibody
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (ERBB2) antibody
  • c-erbB2 antibody
  • c-neu antibody
  • CD340 antibody
  • Erbb-2 antibody
  • HER-2 antibody
  • HER-2/neu antibody
  • HER2 antibody
  • mKIAA3023 antibody
  • MLN 19 antibody
  • Neu antibody
  • NGL antibody
  • TKR1 antibody

Protein level used designations for ERBB2

receptor tyrosine-protein kinase erbB-2 , Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog) , C-erbB-2 , NEU proto-oncogene , epidermal growth factor receptor-related protein , p185erbB2 , p185neu , proto-oncogene NEU , proto-oncogene c-ErbB-2 , v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog , c-erb B2/neu protein , herstatin , metastatic lymph node gene 19 protein , neuro/glioblastoma derived oncogene homolog , neuroblastoma/glioblastoma derived oncogene homolog , proto-oncogene Neu , tyrosine kinase-type cell surface receptor HER2 , Neu oncogene , avian erythroblastosis oncogene B 2 , c-erbB-2 , erbB-2

GENE ID SPECIES
426130 Gallus gallus
24337 Rattus norvegicus
2064 Homo sapiens
13866 Mus musculus
403883 Canis lupus familiaris
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