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|Antigen||V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies|
|Epitope||AA 23-652 Alternatives|
|Conjugate||This HER2 antibody is conjugated to PE Alternatives|
Flow Cytometry (FACS)
|3 references available|
|Supplier||Log in to see|
Product Details anti-HER2 AntibodyTarget Details HER2 Application Details Handling References for anti-HER2 antibody (ABIN4896633) Images
|Specificity||Detects human ErbB2/Her2 in ELISAs and Western blots. In ELISAs and Western blots, this antibody does not cross-react with recombinant human (rh) EGF R, rhErbB3, or rhErbB4.|
|Purification||Protein A or G purified from hybridoma culture supernatant|
|Immunogen||Mouse myeloma cell line NS0-derived recombinant human ErbB2/Her2, Thr23-Thr652, Accession # P04626|
Target Details HER2Product Details anti-HER2 Antibody Application Details Handling References for anti-HER2 antibody (ABIN4896633) Images back to top
|Alternative Name||ErbB2/Her2 (ERBB2 Antibody Abstract)|
|Background||Alternative Names: CD340, CD340 antigen, c-erb B2/neu protein, EC 2.7.10, EGFR2, HER2, HER-2, HER2EC 126.96.36.199, herstatin, Metastatic lymph node gene 19 protein, MLN 19, MLN19, Neu Oncogene, NEUHER-2/neu, neuroblastoma/glioblastoma derived oncogene homolog, NGL, NGLTKR1, p185erbB2, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, receptor tyrosine-protein kinase erbB-2, TKR1, Tyrosine kinase-type cell surface receptor HER2, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2(neuro/glioblastoma derived oncogene homolog), v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastomaderived oncogene homolog (avian)|
|Pathways||RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development|
Application DetailsProduct Details anti-HER2 Antibody Target Details HER2 Handling References for anti-HER2 antibody (ABIN4896633) Images back to top
|Application Notes||Flow Cytometry 10 uL/10^6 cells|
|Restrictions||For Research Use only|
HandlingProduct Details anti-HER2 Antibody Target Details HER2 Application Details References for anti-HER2 antibody (ABIN4896633) Images back to top
|Buffer||Supplied in a saline solution containing BSA and Sodium Azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.|
|Storage Comment||Protect from light. Do not freeze. 12 months from date of receipt,2°C to 8°C as supplied.|
|Expiry Date||12 months|
References for anti-HER2 antibody (ABIN4896633)Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling Images back to top
|Product cited in:||
Sie, den Dunnen, Lourens, Meeuwsen-de Boer, Scherpen, Zomerman, Kampen, Hoving, de Bont: "Growth-factor-driven rescue to receptor tyrosine kinase (RTK) inhibitors through Akt and Erk phosphorylation in pediatric low grade astrocytoma and ependymoma." in: PLoS ONE, Vol. 10, Issue 3, pp. e0122555, 2015 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).
Nakanishi, Chumsri, Khakpour, Brodie, Leyland-Jones, Hamburger, Ross, Burger: "Side-population cells in luminal-type breast cancer have tumour-initiating cell properties, and are regulated by HER2 expression and signalling." in: British journal of cancer, Vol. 102, Issue 5, pp. 815-26, 2010 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).
Dai, Tiwari, Wu, Su, Wang, Liu, Ashby, Huang, Robey, Liang, Chen, Shi, Ambudkar, Chen, Fu: "Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2." in: Cancer research, Vol. 68, Issue 19, pp. 7905-14, 2008 Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).
ImagesProduct Details anti-HER2 Antibody Target Details HER2 Application Details Handling References for anti-HER2 antibody (ABIN4896633) back to top