You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Human HER2 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended HER2 Antibody (supplied by: Log in to see )

Antigen
V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
  • c-erbB2
  • c-neu
  • CD340
  • Erbb-2
  • HER-2
  • HER-2/neu
  • HER2
  • mKIAA3023
  • MLN 19
  • NEU
  • Neu
  • NGL
  • TKR1
Epitope
AA 660-700, pThr686
116
82
64
54
54
51
51
44
36
32
32
29
20
20
20
20
20
19
19
19
19
19
19
18
18
18
15
14
14
14
13
13
12
12
10
10
9
8
8
8
7
7
7
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
5
5
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
1145
406
233
24
12
4
3
3
3
3
2
2
1
1
1
Host
Rabbit
936
351
19
18
5
5
Clonality
Polyclonal
Conjugate
This HER2 antibody is un-conjugated
67
62
53
45
45
41
9
9
8
8
8
8
8
8
8
2
2
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
623
514
323
319
215
181
133
112
89
45
21
17
12
6
6
5
5
5
3
3
2
2
1
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN752398
$ 291.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00088963145 ABIN725345 IF (p) IHC (p) Rabbit IgG AA 1210-1255 Log in to see Polyclonal
0.00088963145 ABIN678068 IF (p) IHC (p) Rabbit IgG AA 160-200 Log in to see Polyclonal
0.00088963145 ABIN2814275 IF (p) Alexa Fluor 594 Rabbit IgG AA 660-700, pThr686 Log in to see Polyclonal
0.00088963145 ABIN880019 IF (p) Alexa Fluor 555 Rabbit IgG AA 660-700, pThr686 Log in to see Polyclonal
0.00088963145 ABIN880022 IF (p) Alexa Fluor 350 Rabbit IgG AA 660-700, pThr686 Log in to see Polyclonal
0.00088963145 ABIN880020 IF (p) Alexa Fluor 647 Rabbit IgG AA 660-700, pThr686 Log in to see Polyclonal
0.00088963145 ABIN880023 IF (p) Alexa Fluor 488 Rabbit IgG AA 660-700, pThr686 Log in to see Polyclonal
0.00088963145 ABIN752404 IF (p) Cy7 Rabbit IgG AA 660-700, pThr686 Log in to see Polyclonal
0.00088963145 ABIN752401 IF (p) Cy3 Rabbit IgG AA 660-700, pThr686 Log in to see Polyclonal
0.00088963145 ABIN752402 IF (p) Cy5 Rabbit IgG AA 660-700, pThr686 Log in to see Polyclonal
0.00088963145 ABIN752403 IF (p) Cy5.5 Rabbit IgG AA 660-700, pThr686 Log in to see Polyclonal
0.00088963145 ABIN752405 IF (p) FITC Rabbit IgG AA 660-700, pThr686 Log in to see Polyclonal
0.00088963145 ABIN2814267 IF (p) Alexa Fluor 594 Rabbit IgG AA 1210-1255 Log in to see Polyclonal
0.00088963145 ABIN878848 IF (p) Alexa Fluor 647 Rabbit IgG pTyr1221, pTyr1222 Log in to see Polyclonal
0.00088963145 ABIN878849 IF (p) Alexa Fluor 555 Rabbit IgG pTyr1221, pTyr1222 Log in to see Polyclonal
0.00088963145 ABIN878850 IF (p) Alexa Fluor 488 Rabbit IgG pTyr1221, pTyr1222 Log in to see Polyclonal
0.00088963145 ABIN878852 IF (p) Alexa Fluor 350 Rabbit IgG pTyr1221, pTyr1222 Log in to see Polyclonal
0.00088963145 ABIN725349 IF (p) Cy5 Rabbit IgG AA 1210-1255 Log in to see Polyclonal
0.00088963145 ABIN725348 IF (p) Cy3 Rabbit IgG AA 1210-1255 Log in to see Polyclonal
0.00088963145 ABIN725350 IF (p) Cy5.5 Rabbit IgG AA 1210-1255 Log in to see Polyclonal

Similar anti-HER2 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
Dot Blot (DB) 19 Antibodies 113 Antibodies
ELISA 68 Antibodies 152 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies 6 Antibodies
Flow Cytometry (FACS) 4 Antibodies 4 Antibodies
Immunochromatography (IC) 3 Antibodies
Immunocytochemistry (ICC) 7 Antibodies
Immunofluorescence (IF) 48 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 45 Antibodies
Immunohistochemistry (IHC) 84 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 43 Antibodies
Immunoprecipitation (IP) 26 Antibodies
Western Blotting (WB) 142 Antibodies

General

Antigen V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
Epitope AA 660-700, pThr686
(116), (82), (64), (54), (54), (51), (51), (44), (36), (32), (32), (29), (20), (20), (20), (20), (20), (19), (19), (19), (19), (19), (19), (18), (18), (18), (15), (14), (14), (14), (13), (13), (12), (12), (10), (10), (9), (8), (8), (8), (7), (7), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (5), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(1145), (406), (233), (24), (12), (4), (3), (3), (3), (3), (2), (2), (1), (1), (1)
Host Rabbit
(936), (351), (19), (18), (5), (5)
Clonality
Polyclonal
Conjugate This HER2 antibody is un-conjugated
(67), (62), (53), (45), (45), (41), (9), (9), (8), (8), (8), (8), (8), (8), (8), (2), (2), (1)
Application Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(623), (514), (323), (319), (215), (181), (133), (112), (89), (45), (21), (17), (12), (6), (6), (5), (5), (5), (3), (3), (2), (2), (1), (1), (1), (1)
Supplier Log in to see

Product Details anti-HER2 Antibody

Target Details HER2 Application Details Handling Images
Specificity This phosphorylation site is homologous to that of Thr687 in Mouse and Thr688 in Rat.
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic phosphopeptide derived from human HER2 around the phosphorylation site of Thr686
Isotype IgG

Target Details HER2

Product Details anti-HER2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Her2 (ERBB2 Antibody Abstract)
Background

Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Regulates outgrowth and stabilization of peripheral microtubules (MTs). Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and CLASP2, allowing its association with the cell membrane. In turn, membrane-bound APC allows the localization of MACF1 to the cell membrane, which is required for microtubule capture and stabilization. In the nucleus is involved in transcriptional regulation. Associates with the 5'-TCAAATTC-3' sequence in the PTGS2/COX-2 promoter and activates its transcription. Implicated in transcriptional activation of CDKN1A, the function involves STAT3 and SRC. Involved in the transcription of rRNA genes by RNA Pol I and enhances protein synthesis and cell growth.

Subcellular location: Cytoplasm


Synonyms: NEU, NGL, HER2, TKR1, CD340, HER-2, MLN 19, HER-2/neu, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2, ERBB2, MLN19
Gene ID 2064
UniProt P04626
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-HER2 Antibody Target Details HER2 Handling Images back to top
Application Notes WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-HER2 Antibody Target Details HER2 Application Details Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

Images

Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-HER2 antibody (V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian)) (AA 660-700) (ABIN752398) Formalin-fixed and paraffin embedded human kidney labeled with Rabbit Anti Phospho-HE...