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anti-Human HER2 antibody for Immunohistochemistry (Acetone-fixed)

Recommended HER2 Antibody (supplied by: Log in to see )

Antigen
V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
  • CD340
  • HER-2
  • HER-2/neu
  • HER2
  • MLN 19
  • NEU
  • NGL
  • TKR1
  • Erbb-2
  • Neu
  • c-erbB2
  • c-neu
  • mKIAA3023
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog
  • v-erb-b2 avian erythroblastic leukemia viral oncogene 2
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
  • ERBB2
  • Erbb2
Reactivity
Human
1354
499
333
35
34
15
13
8
6
5
4
3
3
3
2
1
1
1
1
1
Host
Rat
996
503
28
17
10
5
1
Clonality
Monoclonal
Conjugate
This HER2 antibody is un-conjugated
73
64
60
54
45
41
18
18
10
10
10
9
9
8
8
8
8
8
8
7
7
7
7
7
7
7
7
6
3
2
2
Application
Immunohistochemistry (Acetone-fixed) (IHC (af)), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
705
609
327
322
308
297
240
127
111
102
87
21
17
14
6
5
5
5
4
3
3
3
3
2
1
1
1
1
1
Options
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Catalog No. ABIN2166947
$ 480.52
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2166948 IHC (af) IHC (fp) FACS IP WB Rat IgG2a Log in to see
1 ABIN2166402 IHC (af) ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN2166950 IHC (af) Rat IgG2b Log in to see
1 ABIN2166949 IHC (af) Rat IgG2b Log in to see

Similar anti-HER2 Antibodies

Application / Reactivity Human
Cellular Assay (CA) 1 Antibodies
Cytometry by Time of Flight (CyTOF) 14 Antibodies
Dot Blot (DB) 191 Antibodies
ELISA 469 Antibodies
ELISA (Capture) 3 Antibodies
Enzyme Immunoassay (EIA) 17 Antibodies
Flow Cytometry (FACS) 288 Antibodies
Functional Studies (Func) 5 Antibodies
Immunoassay (IA) 1 Antibodies
Immunochromatography (IC) 5 Antibodies
Immunocytochemistry (ICC) 87 Antibodies
Immunoelectron Microscopy (IEM) 5 Antibodies
Immunofluorescence (IF) 308 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 3 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 102 Antibodies
Immunohistochemistry (IHC) 324 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 5 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 2 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 3 Antibodies

General

Antigen V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
Reactivity Human
(1354), (499), (333), (35), (34), (15), (13), (8), (6), (5), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Host Rat
(996), (503), (28), (17), (10), (5), (1)
Clonality
Monoclonal
Conjugate This HER2 antibody is un-conjugated
(73), (64), (60), (54), (45), (41), (18), (18), (10), (10), (10), (9), (9), (8), (8), (8), (8), (8), (8), (7), (7), (7), (7), (7), (7), (7), (7), (6), (3), (2), (2)
Application Immunohistochemistry (Acetone-fixed) (IHC (af)), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)), Flow Cytometry (FACS), Immunoprecipitation (IP), Western Blotting (WB)
(705), (609), (327), (322), (308), (297), (240), (127), (111), (102), (87), (21), (17), (14), (6), (5), (5), (5), (4), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1)
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Product Details anti-HER2 Antibody

Target Details HER2 Application Details Handling Images
Specificity This antibody recognises epitope E of human HER2/neu, otherwise known as CD340 and c-ErbB-2, a proto-oncogene expressed at the cell surface of a range of tumour cells, which is often associated with poor prognosis, and an increased risk of metastasis.

HER2/neu is used in conjunction with antibodies recognising both Estrogen and Progesterone receptors, for the classification of breast cancer tumours, and to determine patient prognosis and course of treatment.

Excessive HER2/neu is present in around 20 % to 25 % of invasive breast cancers, referred to as HER2-positive cancer, and can help determine whether drugs such as trastuzumab (Herceptin) or lapatinib (Tykerb), might be beneficial.
Predicted Reactivity Human
Characteristics Rat Anti Human Cd340
Protein Size: 1225
Purification Purified IgG prepared by affinity chromatography on Protein G
Isotype IgG2a

Target Details HER2

Product Details anti-HER2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name ERBB2 (ERBB2 Antibody Abstract)
Background Rat Anti Human Cd340
Gene ID 2064
NCBI Accession NP_001005862
UniProt P04626
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-HER2 Antibody Target Details HER2 Handling Images back to top
Application Notes Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x106 cells in 100 μL.
Restrictions For Research Use only

Handling

Product Details anti-HER2 Antibody Target Details HER2 Application Details Images back to top
Format Liquid
Handling Advice Avoid repeat freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment Store at +4 °C or at -20 °C if preferred.
This product should be stored undiluted.
Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.