anti-Human HER2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended HER2 Antibody (supplied by: Log in to see )

Antigen
V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
  • CD340
  • HER-2
  • HER-2/neu
  • HER2
  • MLN 19
  • NEU
  • NGL
  • TKR1
  • Erbb-2
  • Neu
  • c-erbB2
  • c-neu
  • mKIAA3023
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog
  • v-erb-b2 avian erythroblastic leukemia viral oncogene 2
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
  • ERBB2
  • Erbb2
Epitope
pTyr1248
104
81
72
70
56
54
53
48
46
35
26
24
22
22
20
20
20
20
20
20
20
20
20
19
19
19
19
18
17
15
13
13
13
12
11
8
8
8
8
8
7
7
6
6
6
5
5
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
1348
495
329
36
34
15
13
8
6
5
4
3
3
3
2
1
1
1
1
1
Host
Rabbit
980
511
30
16
12
5
1
Clonality
Polyclonal
Conjugate
This HER2 antibody is un-conjugated
76
66
59
54
46
41
19
19
12
12
11
10
10
9
8
8
8
8
8
7
7
7
7
7
7
7
7
6
3
2
2
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
701
596
310
310
309
296
247
138
110
102
88
21
19
14
8
6
6
5
5
3
3
3
2
1
1
1
1
1
1
Supplier
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Catalog No. ABIN4309121
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
13.875275 ABIN967459 IHC (fro) IHC (p) IP WB Mouse IgG1 AA 1242-1255 Log in to see 3B5 9
13.875275 ABIN151232 IHC (p) IP IHC WB Rabbit AA 975-1025 Log in to see Polyclonal 1
13.875275 ABIN4309125 ICC IF IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal 2
13.875275 ABIN305740 IHC (fro) IHC (p) IP WB Rabbit IgG AA 1243-1255 Log in to see Polyclonal
13.875275 ABIN4309139 FACS IF IHC (p) WB Mouse IgG1 kappa Log in to see HRB2-451
13.875275 ABIN295912 ICC IHC (p) WB Chicken IgY AA 153-433 Log in to see Polyclonal
13.875275 ABIN498415 IF IHC (p) WB Rabbit Log in to see Polyclonal
13.875275 ABIN351500 IHC (p) WB Mouse IgG1, kappa C-Term Log in to see SPM495
13.875275 ABIN498846 IHC (p) Rabbit pTyr877 Log in to see Polyclonal
13.875275 ABIN498847 IHC (p) Rabbit pTyr1248 Log in to see Polyclonal
13.875275 ABIN213613 IHC (p) Rabbit Cytoplasmic Domain Log in to see Polyclonal
13.875275 ABIN725345 IF (p) IHC (p) Rabbit IgG AA 1210-1255 Log in to see Polyclonal
13.875275 ABIN4309126 FACS ICC IF IHC IHC (p) WB Mouse IgG2a Log in to see 4F10
13.875275 ABIN498936 IHC (p) Rabbit Log in to see Polyclonal
13.875275 ABIN498935 IHC (p) Rabbit Log in to see Polyclonal
13.875275 ABIN4960167 IHC IHC (p) WB Mouse IgG1 Log in to see CL0268
1 ABIN391947 IHC (p) WB Rabbit Ig AA 1227-1255, C-Term, Tyr1248 Log in to see Polyclonal 4
1 ABIN391945 FACS IHC (p) WB Rabbit Ig AA 21-52, N-Term Log in to see Polyclonal 4
1 ABIN180514 IF IHC (p) IP WB Mouse IgG1 C-Term, pTyr1248 Log in to see PN2A 11
1 ABIN115290 IHC (fro) IHC (p) Rabbit Log in to see Polyclonal 1

Top referenced anti-HER2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-HER2 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
Cytometry by Time of Flight (CyTOF) 2 Antibodies
Dot Blot (DB) 18 Antibodies 107 Antibodies
ELISA 104 Antibodies 176 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies
Flow Cytometry (FACS) 26 Antibodies
Immunochromatography (IC) 3 Antibodies
Immunocytochemistry (ICC) 30 Antibodies
Immunofluorescence (IF) 77 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 51 Antibodies
Immunohistochemistry (IHC) 96 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 24 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 78 Antibodies
Immunoprecipitation (IP) 64 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Western Blotting (WB) 225 Antibodies

General

Antigen V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
Epitope pTyr1248
(104), (81), (72), (70), (56), (54), (53), (48), (46), (35), (26), (24), (22), (22), (20), (20), (20), (20), (20), (20), (20), (20), (20), (19), (19), (19), (19), (18), (17), (15), (13), (13), (13), (12), (11), (8), (8), (8), (8), (8), (7), (7), (6), (6), (6), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(1348), (495), (329), (36), (34), (15), (13), (8), (6), (5), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Host Rabbit
(980), (511), (30), (16), (12), (5), (1)
Clonality
Polyclonal
Conjugate This HER2 antibody is un-conjugated
(76), (66), (59), (54), (46), (41), (19), (19), (12), (12), (11), (10), (10), (9), (8), (8), (8), (8), (8), (7), (7), (7), (7), (7), (7), (7), (7), (6), (3), (2), (2)
Application Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(701), (596), (310), (310), (309), (296), (247), (138), (110), (102), (88), (21), (19), (14), (8), (6), (6), (5), (5), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-HER2 Antibody

Target Details HER2 Application Details Handling ProductDetails: References for anti-HER2 antibody (ABIN4309121) Images
Specificity HER2 (specific to Phospho-Tyr1248) detects endogenous levels of HER2 only when phosphorylated at tyrosine1248.
Purification Immunogen affinity purified
Immunogen The antiserum was produced against synthesized phosphopeptide derived from human HER2 around the phosphorylation site of tyrosine1248 (P-E-YP-L-G).

Target Details HER2

Product Details anti-HER2 Antibody Application Details Handling ProductDetails: References for anti-HER2 antibody (ABIN4309121) Images back to top
Antigen
Alternative Name ErbB2/Her2 (ERBB2 Antibody Abstract)
Background Gene Symbol: ERBB2
Molecular Weight Theoretical MW: 185 kDa
Gene ID 2064
UniProt P04626
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development

Application Details

Product Details anti-HER2 Antibody Target Details HER2 Handling ProductDetails: References for anti-HER2 antibody (ABIN4309121) Images back to top
Application Notes Western Blot 1:500-1:1000, Immunohistochemistry 1:50-1:100, Immunocytochemistry/Immunofluorescence 1:100-1:200, Immunohistochemistry-Paraffin 1:50-1:100The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only

Handling

Product Details anti-HER2 Antibody Target Details HER2 Application Details ProductDetails: References for anti-HER2 antibody (ABIN4309121) Images back to top
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, and 50 % glycerol.
Buffer contains: 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

ProductDetails: References for anti-HER2 antibody (ABIN4309121)

Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling Images back to top
Product cited in:

Scrima, Zito Marino, Oliveira, Marinaro, La Mantia, Rocco, De Marco, Malanga, De Rosa, Rizzuto, Botti, Franco, Zoppoli, Viglietto: "Aberrant Signaling through the HER2-ERK1/2 Pathway is Predictive of Reduced Disease-Free and Overall Survival in Early Stage Non-Small Cell Lung Cancer (NSCLC) Patients." in: Journal of Cancer, Vol. 8, Issue 2, pp. 227-239, 2017

Eden, Ju, Murugesan, Phoenix, Nimmervoll, Tong, Ellison, Finkelstein, Wright, Boulos, Dapper, Thiruvenkatam, Lessman, Taylor, Gilbertson: "Orthotopic models of pediatric brain tumors in zebrafish." in: Oncogene, Vol. 34, Issue 13, pp. 1736-42, 2015 (Sample species: Mouse (Murine)). Further details: Immunohistochemistry (Paraffin-embedded Sections)

Images

Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling ProductDetails: References for anti-HER2 antibody (ABIN4309121) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-HER2 antibody (V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian)) (pTyr1248) (ABIN4309121) Immunohistochemistry-Paraffin: ErbB2/Her2 [p Tyr1248] Antibody [ABIN43091210] - Human...
Western Blotting (WB) image for anti-HER2 antibody (V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian)) (pTyr1248) (ABIN4309121) Western Blot: ErbB2/Her2 [p Tyr1248] Antibody [ABIN43091210] - Analysis of extracts f...
Western Blotting (WB) image for anti-HER2 antibody (V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian)) (pTyr1248) (ABIN4309121) Western Blot: ErbB2/Her2 [p Tyr1248] Antibody [ABIN43091210] - Western blot analysis ...
Immunofluorescence (IF) image for anti-HER2 antibody (V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian)) (pTyr1248) (ABIN4309121) Immunocytochemistry/Immunofluorescence: ErbB2/Her2 [p Tyr1248] Antibody [ABIN43091210...
Western Blotting (WB) image for anti-HER2 antibody (V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian)) (pTyr1248) (ABIN4309121) Western Blot: ErbB2/Her2 [p Tyr1248] Antibody [ABIN43091210] - Analysis of extracts f...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-HER2 antibody (V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian)) (pTyr1248) (ABIN4309121) Immunohistochemistry-Paraffin: ErbB2/Her2 [p Tyr1248] Antibody [ABIN43091210] - Human...