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anti-Human HER2 antibody for Radioimmunoassay

Recommended HER2 Antibody (supplied by: Log in to see )

Antigen
V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
  • c-erbB2
  • c-neu
  • CD340
  • Erbb-2
  • HER-2
  • HER-2/neu
  • HER2
  • mKIAA3023
  • MLN 19
  • NEU
  • Neu
  • NGL
  • TKR1
Reactivity
Human
1322
418
261
24
13
4
3
3
3
3
2
2
1
1
1
Host
Mouse
969
495
25
18
5
5
Clonality
Monoclonal
Conjugate
This HER2 antibody is un-conjugated
74
65
60
52
45
41
17
17
10
10
9
8
8
8
8
8
8
7
7
7
7
7
7
7
7
7
7
2
2
2
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Radioimmunoassay (RIA), Western Blotting (WB)
680
574
331
323
301
281
234
174
103
90
86
21
17
6
6
5
5
5
3
3
2
1
1
1
1
1
Supplier
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Catalog No. ABIN112219
$ 533.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008709465 ABIN2213440 RIA IHC WB Mouse IgG1 Log in to see 5F177

Top referenced anti-HER2 antibody for Radioimmunoassay

Similar anti-HER2 Antibodies

Application / Reactivity Human
Cellular Assay (CA) 1 Antibodies
Dot Blot (DB) 192 Antibodies
ELISA 439 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 17 Antibodies
Flow Cytometry (FACS) 275 Antibodies
Functional Studies (Func) 5 Antibodies
Immunoassay (IA) 1 Antibodies
Immunochromatography (IC) 5 Antibodies
Immunocytochemistry (ICC) 86 Antibodies
Immunoelectron Microscopy (IEM) 6 Antibodies
Immunofluorescence (IF) 302 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 90 Antibodies
Immunohistochemistry (IHC) 329 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 5 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 2 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 3 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 104 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 235 Antibodies

General

Antigen V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
Reactivity Human
(1322), (418), (261), (24), (13), (4), (3), (3), (3), (3), (2), (2), (1), (1), (1)
Host Mouse
(969), (495), (25), (18), (5), (5)
Clonality (Clone)
Monoclonal   ( )
Conjugate This HER2 antibody is un-conjugated
(74), (65), (60), (52), (45), (41), (17), (17), (10), (10), (9), (8), (8), (8), (8), (8), (8), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (2), (2), (2)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Radioimmunoassay (RIA), Western Blotting (WB)
(680), (574), (331), (323), (301), (281), (234), (174), (103), (90), (86), (21), (17), (6), (6), (5), (5), (5), (3), (3), (2), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-HER2 Antibody

Target Details HER2 Application Details Handling References for anti-HER2 Antibody (ABIN112219) Images
Specificity This Monoclonal CB11 antibody reacts with the 185 kDa protein in Immunoblotting.
Purification Supernatant
Immunogen Synthetic peptide (internal domain of the c-erbB-2 oncoprotein)
Clone CB11
Isotype IgG1

Target Details HER2

Product Details anti-HER2 Antibody Application Details Handling References for anti-HER2 Antibody (ABIN112219) Images back to top
Antigen
Alternative Name CD340 / ERBB2 / HER2 (ERBB2 Antibody Abstract)
Background The c-erbB2 proto-oncogene codes for a membrane protein. Several studies report the ampli-fication in carcinomas. Overexpression of c-erbB-2 in breast cancer is a marker for poor prognosis.Synonyms: HER-2, MNL19, NEU, NEU proto-oncogene, NGL, Receptor tyrosine-protein kinase erbB-2, Tyrosine kinase-type cell surface receptor HER2, c-erbB-2, p185erbB2
Gene ID 2064
NCBI Accession NP_001005862
UniProt P04626
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-HER2 Antibody Target Details HER2 Handling References for anti-HER2 Antibody (ABIN112219) Images back to top
Application Notes Immunoblotting. RIA. Immunohistochemistry (1: 5-1: 10) on frozen and paraffin-embedded sections, nopretreatment required. Dilution buffer: PBS with 1 % BSA and 0.1 % Na-Azide. Recommended positive control: Adenocarcinoma of the breast.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-HER2 Antibody Target Details HER2 Application Details References for anti-HER2 Antibody (ABIN112219) Images back to top
Format Liquid
Buffer PBS, 0.09 % Sodium Azide, 1 % BSA
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-HER2 Antibody (ABIN112219)

Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling Images back to top
Background publications

Falck, Gullick: "c-erbB-2 oncogene product staining in gastric adenocarcinoma. An immunohistochemical study." in: The Journal of pathology, Vol. 159, Issue 2, pp. 107-11, 1989

van de Vijver, Mooi, Wisman, Peterse, Nusse: "Immunohistochemical detection of the neu protein in tissue sections of human breast tumors with amplified neu DNA." in: Oncogene, Vol. 2, Issue 2, pp. 175-8, 1988