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anti-Mouse (Murine) HER2 antibody for Dot Blot

Recommended HER2 Antibody (supplied by: Log in to see )

Antigen
V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
  • c-erbB2
  • c-neu
  • CD340
  • Erbb-2
  • HER-2
  • HER-2/neu
  • HER2
  • mKIAA3023
  • MLN 19
  • NEU
  • Neu
  • NGL
  • TKR1
Epitope
pSer1114
120
83
64
54
54
53
51
44
37
36
32
29
21
20
20
20
20
19
19
19
19
19
18
18
18
18
15
14
14
14
13
13
13
12
10
10
9
8
8
8
8
7
7
7
7
7
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
5
5
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine)
1323
417
261
24
13
4
3
3
3
3
2
2
1
1
1
Host
Rabbit
968
496
25
18
5
5
Clonality
Polyclonal
Conjugate
This HER2 antibody is un-conjugated
74
65
60
52
45
41
17
17
10
10
9
8
8
8
8
8
8
7
7
7
7
7
7
7
7
7
7
2
2
2
Application
Dot Blot (DB)
681
574
331
322
302
281
235
174
104
90
86
21
17
6
6
5
5
5
3
3
2
2
1
1
1
1
Supplier
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Catalog No. ABIN1881311
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.63784635 ABIN1881306 DB Rabbit pSer1051 Log in to see Polyclonal 5
0.63784635 ABIN1539719 DB Rabbit Ig pSer999 Log in to see Polyclonal
0.63784635 ABIN1539787 DB Rabbit Ig pTyr1223 Log in to see Polyclonal
0.63784635 ABIN1539699 DB Rabbit Ig pSer26 Log in to see Polyclonal
0.63784635 ABIN2160992 DB Rabbit Ig Fraction pSer999 Log in to see Polyclonal
0.63784635 ABIN2160993 DB Rabbit Ig Fraction pThr1140 Log in to see Polyclonal
0.63784635 ABIN2160994 DB Rabbit Ig Fraction pThr1197 Log in to see Polyclonal
0.63784635 ABIN2160995 DB Rabbit Ig Fraction pTyr1223 Log in to see Polyclonal
0.63784635 ABIN2160990 DB Rabbit Ig Fraction Log in to see Polyclonal
0.63784635 ABIN2160991 DB Rabbit Ig Fraction Log in to see Polyclonal
0.0008934913 ABIN1967212 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG Ser1051, pSer1051 Log in to see Polyclonal
0.0008934913 ABIN1967215 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG Ser1114, pSer1114 Log in to see Polyclonal
0.0008934913 ABIN1967249 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG Ser999, pSer999 Log in to see Polyclonal
0.0008934913 ABIN1967261 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG Tyr1140, pTyr1140 Log in to see Polyclonal
0.0008934913 ABIN1967263 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG Tyr1223, pTyr1223 Log in to see Polyclonal
0.0008934913 ABIN1967262 DB ELISA Alkaline Phosphatase (AP) Rabbit IgG Tyr1197, pTyr1197 Log in to see Polyclonal
0.0008934913 ABIN1967296 DB ELISA APC Rabbit IgG Ser1051, pSer1051 Log in to see Polyclonal
0.0008934913 ABIN1967299 DB ELISA APC Rabbit IgG Ser1114, pSer1114 Log in to see Polyclonal
0.0008934913 ABIN1967333 DB ELISA APC Rabbit IgG Ser999, pSer999 Log in to see Polyclonal
0.0008934913 ABIN1967345 DB ELISA APC Rabbit IgG Tyr1140, pTyr1140 Log in to see Polyclonal

Top referenced anti-HER2 antibody for Dot Blot

  • Mouse (Murine) Polyclonal HER2 Primary Antibody for DB - ABIN1881306 (5 Publications): Cabodi, Tinnirello, Bisaro, Tornillo, del Pilar Camacho-Leal, Forni, Cojoca, Iezzi, Amici, Montani, Eva, Di Stefano, Muthuswamy, Tarone, Turco, Defilippi: p130Cas is an essential transducer element in ErbB2 transformation. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2010 (PubMed)

  • Mouse (Murine) Polyclonal HER2 Primary Antibody for DB - ABIN1881311 (5 Publications): Johnson, Seachrist, DeLeon-Rodriguez, Lozada, Miedler, Abdul-Karim, Keri: HER2/ErbB2-induced breast cancer cell migration and invasion require p120 catenin activation of Rac1 and Cdc42. in The Journal of biological chemistry 2010 (PubMed)

Similar anti-HER2 Antibodies

Application / Reactivity Mouse (Murine)
Dot Blot (DB) 113 Antibodies
ELISA 153 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies
Flow Cytometry (FACS) 11 Antibodies
Immunochromatography (IC) 2 Antibodies
Immunocytochemistry (ICC) 12 Antibodies
Immunofluorescence (IF) 54 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 78 Antibodies
Immunohistochemistry (IHC) 93 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 55 Antibodies
Immunoprecipitation (IP) 26 Antibodies
Western Blotting (WB) 197 Antibodies

General

Antigen V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
Epitope pSer1114
(120), (83), (64), (54), (54), (53), (51), (44), (37), (36), (32), (29), (21), (20), (20), (20), (20), (19), (19), (19), (19), (19), (18), (18), (18), (18), (15), (14), (14), (14), (13), (13), (13), (12), (10), (10), (9), (8), (8), (8), (8), (7), (7), (7), (7), (7), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (5), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine)
(1323), (417), (261), (24), (13), (4), (3), (3), (3), (3), (2), (2), (1), (1), (1)
Host Rabbit
(968), (496), (25), (18), (5), (5)
Clonality (Clone)
Polyclonal   ( )
Conjugate This HER2 antibody is un-conjugated
(74), (65), (60), (52), (45), (41), (17), (17), (10), (10), (9), (8), (8), (8), (8), (8), (8), (7), (7), (7), (7), (7), (7), (7), (7), (7), (7), (2), (2), (2)
Application Dot Blot (DB)
(681), (574), (331), (322), (302), (281), (235), (174), (104), (90), (86), (21), (17), (6), (6), (5), (5), (5), (3), (3), (2), (2), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-HER2 Antibody

Target Details HER2 Application Details Handling References for anti-HER2 Antibody (ABIN1881311) Images
Predicted Reactivity Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification. Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Immunogen This mouse ERBB2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S1114 of mouse ERBB2.
Clone RB40082

Target Details HER2

Product Details anti-HER2 Antibody Application Details Handling References for anti-HER2 Antibody (ABIN1881311) Images back to top
Antigen
Alternative Name ERBB2 (ERBB2 Antibody Abstract)
Background This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.

Synonyms: Erbb2, Kiaa3023, Neu, Receptor tyrosine-protein kinase erbB-2, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, p185erbB2, CD_antigen=CD340, Flags: Precursor
NCBI Accession NP_001003817
UniProt P70424
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-HER2 Antibody Target Details HER2 Handling References for anti-HER2 Antibody (ABIN1881311) Images back to top
Application Notes DB: 1:500
Restrictions For Research Use only

Handling

Product Details anti-HER2 Antibody Target Details HER2 Application Details References for anti-HER2 Antibody (ABIN1881311) Images back to top
Format Liquid
Concentration 0.47 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

References for anti-HER2 Antibody (ABIN1881311)

Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling Images back to top
Product cited in:

Cabodi, Tinnirello, Bisaro, Tornillo, del Pilar Camacho-Leal, Forni, Cojoca, Iezzi, Amici, Montani, Eva, Di Stefano, Muthuswamy, Tarone, Turco, Defilippi: "p130Cas is an essential transducer element in ErbB2 transformation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 24, Issue 10, pp. 3796-808, 2010

Johnson, Seachrist, DeLeon-Rodriguez, Lozada, Miedler, Abdul-Karim, Keri: "HER2/ErbB2-induced breast cancer cell migration and invasion require p120 catenin activation of Rac1 and Cdc42." in: The Journal of biological chemistry, Vol. 285, Issue 38, pp. 29491-501, 2010

Huck, Pontier, Zuo, Muller: "beta1-integrin is dispensable for the induction of ErbB2 mammary tumors but plays a critical role in the metastatic phase of tumor progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 35, pp. 15559-64, 2010

Chuang, Chen, Lin, Veeramani, Kumar, Batra, Tu, Lin: "Human prostatic acid phosphatase, an authentic tyrosine phosphatase, dephosphorylates ErbB-2 and regulates prostate cancer cell growth." in: The Journal of biological chemistry, Vol. 285, Issue 31, pp. 23598-606, 2010

Simeone, Straubinger, Khan, Nalleweg, Cheusova, Hashemolhosseini: "Identification of Erbin interlinking MuSK and ErbB2 and its impact on acetylcholine receptor aggregation at the neuromuscular junction." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 19, pp. 6620-34, 2010

Images

Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling References for anti-HER2 Antibody (ABIN1881311) back to top
Supplier Images
Dot Blot (DB) image for anti-HER2 antibody (V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian)) (pSer1114) (ABIN1881311) Dot blot analysis of mouse ERBB2 Antibody (Phospho S1114) Phospho-specific Pab (ABIN1...