anti-Mouse (Murine) HER2 antibody for Immunofluorescence

Recommended HER2 Antibody (supplied by: Log in to see )

Antigen
V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
  • CD340
  • HER-2
  • HER-2/neu
  • HER2
  • MLN 19
  • NEU
  • NGL
  • TKR1
  • Erbb-2
  • Neu
  • c-erbB2
  • c-neu
  • mKIAA3023
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog
  • v-erb-b2 avian erythroblastic leukemia viral oncogene 2
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
  • ERBB2
  • Erbb2
Epitope
pThr686
101
95
72
69
62
55
55
48
46
35
26
22
21
21
20
20
20
20
20
20
20
20
20
19
19
19
18
17
15
15
13
13
13
12
11
8
8
8
8
8
7
7
6
6
5
5
4
4
4
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
1373
493
324
36
34
15
13
8
6
5
4
3
3
3
2
1
1
1
1
1
Host
Rabbit
1005
512
30
16
12
5
1
Clonality
Polyclonal
Conjugate
This HER2 antibody is un-conjugated
76
66
59
54
46
41
19
19
12
12
11
10
10
9
8
8
8
8
8
7
7
7
7
7
7
7
7
6
3
2
2
Application
Immunofluorescence (IF), ELISA
716
601
318
314
309
308
267
132
112
102
89
21
19
18
8
6
6
5
3
3
3
2
1
1
1
1
1
1
1
Options
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Catalog No. ABIN1531590
$ 302.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
11.176395 ABIN1532607 IF ELISA Rabbit IgG Log in to see Polyclonal 3
11.176395 ABIN1534423 IF IHC ELISA WB Rabbit IgG Log in to see Polyclonal 1
11.176395 ABIN4309121 ICC IF IHC IHC (p) WB Rabbit pTyr1248 Log in to see Polyclonal 2
11.176395 ABIN2957598 IC IF IHC WB Rabbit Log in to see Polyclonal
11.176395 ABIN1532624 IF ELISA Rabbit IgG Log in to see Polyclonal
11.176395 ABIN4309119 ICC IF IHC IHC (p) WB Rabbit pTyr877 Log in to see Polyclonal
11.176395 ABIN4309122 ICC IF IHC IHC (p) WB Rabbit Log in to see Polyclonal
11.176395 ABIN1870165 IF WB Rabbit IgG pTyr1221, pTyr1222 Log in to see Polyclonal
11.176395 ABIN1870167 IF IHC WB Rabbit IgG pTyr1248 Log in to see Polyclonal
11.176395 ABIN2424837 IF IHC WB Rabbit IgG pTyr1248 Log in to see Polyclonal
11.176395 ABIN2424829 IF IHC WB Rabbit IgG pTyr877 Log in to see Polyclonal
1 ABIN196756 IF IHC (p) WB Rabbit pTyr1248 Log in to see Polyclonal 4
1 ABIN197226 IF IHC (p) WB Rabbit AA 1246-1250 Log in to see Polyclonal 4
1 ABIN196748 IF IHC (p) WB Rabbit pTyr877 Log in to see Polyclonal 2
1 ABIN126789 IF WB Mouse IgG1 pTyr1112 Log in to see 19G5
1 ABIN2755561 IC IF IP IHC WB Rabbit C-Term, pTyr1248 Log in to see Polyclonal
1 ABIN362016 IF IHC WB Rabbit IgG pTyr877 Log in to see Polyclonal 3
1 ABIN362024 IF IHC WB Rabbit IgG pTyr1248 Log in to see Polyclonal 1
1 ABIN362620 IF IHC WB Rabbit IgG AA 1246-1250 Log in to see Polyclonal 6
1 ABIN362616 IF IHC WB Rabbit IgG AA 875-879 Log in to see Polyclonal 6

General

Antigen V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) Antibodies
Epitope pThr686
(101), (95), (72), (69), (62), (55), (55), (48), (46), (35), (26), (22), (21), (21), (20), (20), (20), (20), (20), (20), (20), (20), (20), (19), (19), (19), (18), (17), (15), (15), (13), (13), (13), (12), (11), (8), (8), (8), (8), (8), (7), (7), (6), (6), (5), (5), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(1373), (493), (324), (36), (34), (15), (13), (8), (6), (5), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1)
Host Rabbit
(1005), (512), (30), (16), (12), (5), (1)
Clonality
Polyclonal
Conjugate This HER2 antibody is un-conjugated
(76), (66), (59), (54), (46), (41), (19), (19), (12), (12), (11), (10), (10), (9), (8), (8), (8), (8), (8), (7), (7), (7), (7), (7), (7), (7), (7), (6), (3), (2), (2)
Application Immunofluorescence (IF), ELISA
(716), (601), (318), (314), (309), (308), (267), (132), (112), (102), (89), (21), (19), (18), (8), (6), (6), (5), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-HER2 Antibody

Target Details HER2 Application Details Handling References for anti-HER2 antibody (ABIN1531590) Images
Specificity HER2 (Phospho-Thr686) Antibody detects endogenous levels of HER2 only when phosphorylated at Thr686.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation.
Purity > 95 %
Immunogen The antiserum was produced against synthesized peptide derived from human HER2 around the phosphorylation site of Thr686.
Isotype IgG

Target Details HER2

Product Details anti-HER2 Antibody Application Details Handling References for anti-HER2 antibody (ABIN1531590) Images back to top
Antigen
Alternative Name HER2 (ERBB2 Antibody Abstract)
Background Molecular weight of target protein: 137 kDa
Synonyms: C-erbB-2, Epidermal growth factor receptor-related protein, ErbB2, HER2, MLN 19, NEU, NEU proto-oncogene, NGL, Receptor protein- tyrosine kinase erbB-2, Receptor protein-tyrosine kinase erbB-2 precursor, Tyrosine kinase-type cell surface receptor HER2, kinase ErbB2, p185erbB2
Molecular Weight 137 kDa
Gene ID 2064
OMIM 164870
UniProt P04626
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development

Application Details

Product Details anti-HER2 Antibody Target Details HER2 Handling References for anti-HER2 antibody (ABIN1531590) Images back to top
Application Notes IF: 1:100-1:500
ELISA: 1:5000
Optimal working dilution should be determined by the investigator.
Comment

Unigene-Number: Hs.446352 (NCBI Gene Symbol: ERBB2)

Restrictions For Research Use only

Handling

Product Details anti-HER2 Antibody Target Details HER2 Application Details References for anti-HER2 antibody (ABIN1531590) Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 52 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Stable at -20 °C for at least 1 year.
Expiry Date 12 months

References for anti-HER2 antibody (ABIN1531590)

Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling Images back to top
Background publications

Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks." in: Cell, Vol. 127, Issue 3, pp. 635-48, 2006

Yamamoto, Ikawa, Akiyama, Semba, Nomura, Miyajima, Saito, Toyoshima: "Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor." in: Nature, Vol. 319, Issue 6050, pp. 230-4, 1986

King, Kraus, Aaronson: "Amplification of a novel v-erbB-related gene in a human mammary carcinoma." in: Science (New York, N.Y.), Vol. 229, Issue 4717, pp. 974-6, 1985

Images

Product Details anti-HER2 Antibody Target Details HER2 Application Details Handling References for anti-HER2 antibody (ABIN1531590) back to top
Supplier Images
Immunofluorescence (IF) image for anti-V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) (pThr686) antibody (ABIN1531590) Immunofluorescence analysis of HuvEc cells, using HER2 (Phospho-Thr686) Antibody. The...