Browse our HER2 (ERBB2) ELISA Kits

Full name:
V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) ELISA Kits (ERBB2)
On www.antibodies-online.com are 52 V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) ELISA Kits from 18 different suppliers available. Additionally we are shipping HER2 Antibodies (1582) and HER2 Proteins (103) and many more products for this protein. A total of 1821 HER2 products are currently listed.
Synonyms:
c-erbB2, c-neu, CD340, Erbb-2, HER-2, HER-2/neu, HER2, mKIAA3023, MLN 19, Neu, NGL, TKR1
list all ELISA KIts Gene Name GeneID UniProt
ERBB2 24337  
ERBB2 2064 P04626
ERBB2 13866 P70424

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Top referenced HER2 ELISA Kits

  1. Human HER2 ELISA Kit for Sandwich ELISA - ABIN625296 : Laidi, Bouziane, Lakhdar, Khabouze, Rhrab, Zaoui: Salivary expression of soluble HER2 in breast cancer patients with positive and negative HER2 status. in OncoTargets and therapy 2014 (PubMed)

More ELISA Kits for HER2 Interaction Partners

Human V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) interaction partners

  1. Results indicate a mechanism of action for neuromedin U (NmU (show NMU ELISA Kits)) in HER2-overexpressing breast cancer that enhances resistance to HER2-targeted drugs through conferring cancer stem cell (CSC) characteristics and expansion of the CSC phenotype.

  2. the estrogen- (ER), progesterone- (PgR (show PGR ELISA Kits)) and HER2/neu receptor status of the primary tumor with brain metastases in a series of 24 consecutive breast cancer patients, is reported.

  3. tumor-promoting role for CCL2 acting through CCR2 on the tumor microenvironment

  4. We observed correlations between time to tumor relapse and the magnitude of changes of proliferation, luminal B, or HER2-E signatures in metastatic versus primary disease. Although the intrinsic subtype was largely maintained during metastatic progression, luminal/HER2-negative tumors acquired a luminal B or HER2-E profile during metastatic progression, likely reflecting tumor evolution or acquisition of estrogen independ

  5. Results indicate that p110alpha (show PIK3CA ELISA Kits) primarily mediates PI3K (show PIK3CA ELISA Kits)/AKT (show AKT1 ELISA Kits) signaling in HER2+ PTEN deficient breast tumors whereas p110beta conditionally mediates HER2/PI3K (show PIK3CA ELISA Kits) signaling in the absence of p110alpha (show PIK3CA ELISA Kits).

  6. Data indicate that co-inhibition of FGFR1 (show FGFR1 ELISA Kits) and HER2 or PDGFRalpha led to enhanced drug responses.

  7. Her-2-positive metastatic breast cancers, PTEN positivity was significantly associated with progressive disease, but not with PFS or OS

  8. This study demonstrated that discordance between the HER2 expression of circulating tumor cells (CTCs) and that of the primary tumor frequently occurs in early breast cancer. Future follow-up evaluation will assess whether this discrepancy may contribute to trastuzumab resistance.

  9. Increased ezrin (show EZR ELISA Kits) and HER2 expression in patients with salivary gland carcinomas represents a high-grade histopathological subtype.

  10. our findings identified a subset of EGFR (show EGFR ELISA Kits) and HER2 exon 20 insertion mutations that are sensitive to existing covalent quinazoline-based EGFR (show EGFR ELISA Kits)/HER2 inhibitors, with implications for current clinical treatment and next-generation small-molecule inhibitors.

Mouse (Murine) V-Erb-B2 erythroblastic Leukemia Viral Oncogene Homolog 2, Neuro/glioblastoma Derived Oncogene Homolog (Avian) (ERBB2) interaction partners

  1. investigations revealed that NUMB (show NUMB ELISA Kits) and NUMBL (show NUMBL ELISA Kits) interacted with small GTPase (show RACGAP1 ELISA Kits) Rab7 (show RAB7A ELISA Kits) to transition ERBB2 from early to late endosome for degradation.

  2. Combined targeting of TGF-beta (show TGFB1 ELISA Kits), EGFR (show EGFR ELISA Kits) and HER2 signaling suppresses lymphangiogenesis and metastasis in a pancreatic ductal adenocarcinoma model.

  3. The conjugation of benzylguanine-modified auristatin F to EGFR (show EGFR ELISA Kits)-specific 425(scFv)-SNAP and HER2-specific alphaHER2(scFv)-SNAP resulted in two potent recombinant antibody-drug conjugates that specifically killed breast cancer cell lines by inducing apoptosis when applied at nanomolar concentrations.

  4. ErbB2 is required for neonatal cardiomyocyte proliferation. ErbB2 conditional knockout heart exhibited an upregulation of negative cell cycle regulators.

  5. Despite previous evidence suggesting that ErbB (show EGFR ELISA Kits) receptors can bind and activate IRSs, our findings indicate that ErbB2 does not cooperate with the IRS (show IARS ELISA Kits) pathway in mouse breast cancer model.

  6. It was suggested that transgenic HER-2/neu involves in initiation of malignization of mammary epithelial cells but also in acceleration of age-related hormonal and metabolic changes in turn promoting mammary carcinogenesis

  7. Study showed that suppression of STAT3 (show STAT3 ELISA Kits), STAT5 (show STAT5A ELISA Kits), and STAT6 (show STAT6 ELISA Kits) and overexpression of the proapoptotic factor STAT1 (show STAT1 ELISA Kits), which provides p53 (show TP53 ELISA Kits)-mediated apoptosis, are the causes for increasing the number of apoptotic neurons in physiological aging. HER-2 tyrosine kinase receptor (show KDR ELISA Kits) overexpression promotes neuronal survival through activation of STAT (show STAT1 ELISA Kits)-signaling pathway with simultaneous suppression of the proapoptotic factor STAT1 (show STAT1 ELISA Kits)

  8. that myocardial ErbB2 and beta-adrenergic receptors signalling are linked in a feedback loop with beta-adrenergic receptors activation leading to increased ErbB2 expression and activity

  9. Metformin inhibits breast tumor angiogenesis and suggest role of HIF-1alpha (show HIF1A ELISA Kits)-VEGF (show VEGFA ELISA Kits) signaling axis in mediating HER2-induced tumor angiogenesis.

  10. In trastuzumab-doxorubicin combination therapy in a murine model of HER2+ breast cancer.

HER2 (ERBB2) Antigen Profile

Antigen Summary

This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.

Alternative names and synonyms associated with HER2 (ERBB2)

  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (ERBB2) Elisa Kit
  • v-erb-b2 avian erythroblastic leukemia viral oncogene 2 (Erbb2) Elisa Kit
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (ERBB2) Elisa Kit
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (Erbb2) Elisa Kit
  • v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) (ERBB2) Elisa Kit
  • c-erbB2 Elisa Kit
  • c-neu Elisa Kit
  • CD340 Elisa Kit
  • Erbb-2 Elisa Kit
  • HER-2 Elisa Kit
  • HER-2/neu Elisa Kit
  • HER2 Elisa Kit
  • mKIAA3023 Elisa Kit
  • MLN 19 Elisa Kit
  • Neu Elisa Kit
  • NGL Elisa Kit
  • TKR1 Elisa Kit

Protein level used designations for ERBB2

receptor tyrosine-protein kinase erbB-2 , Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog) , C-erbB-2 , NEU proto-oncogene , epidermal growth factor receptor-related protein , p185erbB2 , p185neu , proto-oncogene NEU , proto-oncogene c-ErbB-2 , v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog , c-erb B2/neu protein , herstatin , metastatic lymph node gene 19 protein , neuro/glioblastoma derived oncogene homolog , neuroblastoma/glioblastoma derived oncogene homolog , proto-oncogene Neu , tyrosine kinase-type cell surface receptor HER2 , Neu oncogene , avian erythroblastosis oncogene B 2 , c-erbB-2 , erbB-2

GENE ID SPECIES
426130 Gallus gallus
24337 Rattus norvegicus
2064 Homo sapiens
13866 Mus musculus
403883 Canis lupus familiaris
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