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anti-Human IGF1R antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended IGF1R Antibody (supplied by: Log in to see )

Antigen
Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibodies
  • A330103N21Rik
  • CD221
  • D930020L01
  • DKFZp469I0618
  • hyft
  • IGF-1R
  • igf-1r
  • IGF1R
  • IGFIR
  • IGFIRC
  • IGFR
  • IGFR1
  • JTK13
  • xIGF-1R
  • xigf1r
  • xIGFR
Epitope
N-Term
31
29
28
26
24
21
19
14
14
13
13
13
13
13
12
8
7
6
5
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
429
172
170
2
2
2
2
1
1
Host
Rabbit
295
129
2
2
Clonality
Polyclonal
Conjugate
This IGF1R antibody is un-conjugated
20
19
18
16
10
9
8
8
8
8
8
8
8
8
6
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
263
107
100
88
70
58
38
29
9
8
6
4
3
3
2
1
1
1
1
Supplier
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Catalog No. ABIN359877
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.34475207 ABIN364299 IHC (p) IP WB Mouse IgG2a AA 1264-1367 Log in to see JBW902
0.34475207 ABIN498849 IHC (p) Rabbit pTyr980 Log in to see Polyclonal
0.00089475926 ABIN726575 IF (p) IHC (p) WB Rabbit IgG AA 260-290 Log in to see Polyclonal 2
0.00089475926 ABIN181732 FACS IHC (p) WB Mouse IgG1 Chain alpha Log in to see 1H7 3
0.00089475926 ABIN111141 Func FACS IHC (p) WB Mouse IgG1 Chain alpha Log in to see 1H7 4
0.00089475926 ABIN391990 IHC (p) WB Rabbit Ig AA 19-51, N-Term Log in to see Polyclonal 5
0.00089475926 ABIN652374 FACS IF IHC (p) WB Rabbit Ig AA 51-77, N-Term Log in to see Polyclonal 3
0.00089475926 ABIN197576 IHC (p) WB Rabbit Tyr1280 Log in to see Polyclonal 2
0.00089475926 ABIN614475 IHC (p) IP WB Mouse IgG2a AA 1264-1367 Log in to see JBW902
0.00089475926 ABIN802203 IF (p) IHC (p) WB Rabbit IgG AA 960-1000, pTyr980 Log in to see Polyclonal 1
0.00089475926 ABIN319345 IHC (p) WB Rabbit Tyr1346 Log in to see Polyclonal 4
0.00089475926 ABIN265475 IHC (p) WB Rabbit Log in to see Polyclonal
0.00089475926 ABIN153446 IHC (p) IHC Mouse IgG1 Log in to see 24-31
0.00089475926 ABIN614510 EIA IHC (fro) FACS IHC (p) WB Mouse IgG1 Log in to see n-a
0.00089475926 ABIN2878959 IHC (p) ELISA WB Rabbit IgG AA 1126-1175 Log in to see Polyclonal
0.00089475926 ABIN2888441 IHC (p) IP ELISA WB Rabbit IgG pTyr1161 Log in to see Polyclonal
0.00089475926 ABIN3044138 IHC (p) WB Rabbit IgG AA 1353-1367, C-Term Log in to see Polyclonal
0.00089475926 ABIN802218 IF (p) IHC (p) WB Rabbit IgG AA 1270-1285, pTyr1280 Log in to see Polyclonal
0.00089475926 ABIN1106090 IHC (p) WB Mouse IgG2b Log in to see 3C8B1 3
0.00089475926 ABIN197242 IF IHC (p) WB Rabbit Tyr1161 Log in to see Polyclonal

Top referenced anti-IGF1R antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-IGF1R Antibodies

Application / Reactivity Human
Depletion (Dep) 2 Antibodies
ELISA 107 Antibodies
Enzyme Immunoassay (EIA) 7 Antibodies
Flow Cytometry (FACS) 58 Antibodies
Fluorescence Microscopy (FM) 1 Antibodies
Functional Studies (Func) 9 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 8 Antibodies
Immunofluorescence (IF) 29 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 88 Antibodies
Immunohistochemistry (IHC) 101 Antibodies
Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp)) 3 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 72 Antibodies
Immunoprecipitation (IP) 39 Antibodies
Intracellular Staining (ICS) 1 Antibodies
Neutralization (Neut) 3 Antibodies

General

Antigen Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibodies
Epitope N-Term
(31), (29), (28), (26), (24), (21), (19), (14), (14), (13), (13), (13), (13), (13), (12), (8), (7), (6), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(429), (172), (170), (2), (2), (2), (2), (1), (1)
Host Rabbit
(295), (129), (2), (2)
Clonality
Polyclonal
Conjugate This IGF1R antibody is un-conjugated
(20), (19), (18), (16), (10), (9), (8), (8), (8), (8), (8), (8), (8), (8), (6)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(263), (107), (100), (88), (70), (58), (38), (29), (9), (8), (6), (4), (3), (3), (2), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-IGF1R Antibody

Target Details IGF1R Application Details Handling References for anti-IGF1R Antibody (ABIN359877) Images
Specificity This antibody reacts to IGF1 Receptor (IGF1R).
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human IGF1R.
Isotype Ig

Target Details IGF1R

Product Details anti-IGF1R Antibody Application Details Handling References for anti-IGF1R Antibody (ABIN359877) Images back to top
Antigen
Alternative Name CD221 / IGF1R (IGF1R Antibody Abstract)
Background The IGF1R receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.Synonyms: IGF-I receptor, IGF1 Receptor, Insulin-like growth factor 1 receptor
Gene ID 3480, 9606
UniProt P08069
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways RTK Signaling

Application Details

Product Details anti-IGF1R Antibody Target Details IGF1R Handling References for anti-IGF1R Antibody (ABIN359877) Images back to top
Application Notes ELISA: 1/1,000. Western Blot: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-IGF1R Antibody Target Details IGF1R Application Details References for anti-IGF1R Antibody (ABIN359877) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-IGF1R Antibody (ABIN359877)

Product Details anti-IGF1R Antibody Target Details IGF1R Application Details Handling Images back to top
Background publications

Song, Barnes, Zhang, Bao, Kumar, Santen: "The role of Shc and insulin-like growth factor 1 receptor in mediating the translocation of estrogen receptor alpha to the plasma membrane." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 7, pp. 2076-81, 2004

Staes, Demol, Van Damme, Martens, Vandekerckhove, Gevaert: "Global differential non-gel proteomics by quantitative and stable labeling of tryptic peptides with oxygen-18." in: Journal of proteome research, Vol. 3, Issue 4, pp. 786-91, 2004

Lu, Zi, Zhao, Pollak: "Overexpression of ErbB2 receptor inhibits IGF-I-induced Shc-MAPK signaling pathway in breast cancer cells." in: Biochemical and biophysical research communications, Vol. 313, Issue 3, pp. 709-15, 2003

Hakam, Fang, Karl, Coppola: "Coexpression of IGF-1R and c-Src proteins in human pancreatic ductal adenocarcinoma." in: Digestive diseases and sciences, Vol. 48, Issue 10, pp. 1972-8, 2003

Li, Higashi, Itabe, Song, Du, Delafontaine: "Insulin-like growth factor-1 receptor activation inhibits oxidized LDL-induced cytochrome C release and apoptosis via the phosphatidylinositol 3 kinase/Akt signaling pathway." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 23, Issue 12, pp. 2178-84, 2003

Images

Product Details anti-IGF1R Antibody Target Details IGF1R Application Details Handling References for anti-IGF1R Antibody (ABIN359877) back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-IGF1R antibody (Insulin-Like Growth Factor 1 Receptor) (N-Term) (ABIN359877) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...
Western Blotting (WB) image for anti-IGF1R antibody (Insulin-Like Growth Factor 1 Receptor) (N-Term) (ABIN359877) Western blot analysis of anti-IGF1R Antibody (N-term) in SK-BR-3 cell line lysates (3...