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anti-Mouse (Murine) IGF1R antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended IGF1R Antibody (supplied by: Log in to see )

Antigen
Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibodies
  • A330103N21Rik
  • CD221
  • D930020L01
  • DKFZp469I0618
  • hyft
  • IGF-1R
  • igf-1r
  • IGF1R
  • IGFIR
  • IGFIRC
  • IGFR
  • IGFR1
  • JTK13
  • xIGF-1R
  • xigf1r
  • xIGFR
Epitope
pTyr980
31
30
28
26
24
21
18
14
14
13
13
13
13
13
12
8
7
6
5
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
429
171
169
2
2
2
2
1
1
Host
Rabbit
295
129
2
2
Clonality
Polyclonal
Conjugate
This IGF1R antibody is un-conjugated
20
19
18
16
10
9
8
8
8
8
8
8
8
8
6
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
264
107
100
88
70
58
38
29
9
8
7
4
3
3
2
1
1
1
1
Supplier
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Catalog No. ABIN498849
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089488085 ABIN726575 IF (p) IHC (p) WB Rabbit IgG AA 260-290 Log in to see Polyclonal 2
0.00089488085 ABIN197576 IHC (p) WB Rabbit Tyr1280 Log in to see Polyclonal 2
0.00089488085 ABIN614475 IHC (p) IP WB Mouse IgG2a AA 1264-1367 Log in to see JBW902
0.00089488085 ABIN802203 IF (p) IHC (p) WB Rabbit IgG AA 960-1000, pTyr980 Log in to see Polyclonal 1
0.00089488085 ABIN319345 IHC (p) WB Rabbit Tyr1346 Log in to see Polyclonal 4
0.00089488085 ABIN265475 IHC (p) WB Rabbit Log in to see Polyclonal
0.00089488085 ABIN802218 IF (p) IHC (p) WB Rabbit IgG AA 1270-1285, pTyr1280 Log in to see Polyclonal
0.00089488085 ABIN197242 IF IHC (p) WB Rabbit Tyr1161 Log in to see Polyclonal
0.00089488085 ABIN743153 IF (p) IHC (p) WB Rabbit IgG AA 1130-1180, pTyr1161 Log in to see Polyclonal
0.00089488085 ABIN318045 EIA IHC (p) IP WB Rabbit pTyr1161 Log in to see Polyclonal
0.00089488085 ABIN671826 IF (p) IHC (p) WB Rabbit IgG AA 1300-1367 Log in to see Polyclonal
0.00089488085 ABIN1387293 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.00089488085 ABIN802227 IHC (p) WB HRP Rabbit IgG AA 1270-1285, pTyr1280 Log in to see Polyclonal
0.00089488085 ABIN802220 IHC (p) WB Biotin Rabbit IgG AA 1270-1285, pTyr1280 Log in to see Polyclonal
0.00089488085 ABIN743162 IHC (p) WB HRP Rabbit IgG AA 1130-1180, pTyr1161 Log in to see Polyclonal
0.00089488085 ABIN743155 IHC (p) WB Biotin Rabbit IgG AA 1130-1180, pTyr1161 Log in to see Polyclonal
0.00089488085 ABIN802235 IHC (p) WB Biotin Rabbit IgG pTyr1165, pTyr1166 Log in to see Polyclonal
0.00089488085 ABIN802242 IHC (p) WB HRP Rabbit IgG pTyr1165, pTyr1166 Log in to see Polyclonal
0.00089488085 ABIN671835 IHC (p) WB HRP Rabbit IgG AA 1300-1367 Log in to see Polyclonal
0.00089488085 ABIN671828 IHC (p) WB Biotin Rabbit IgG AA 1300-1367 Log in to see Polyclonal

Top referenced anti-IGF1R antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-IGF1R Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 264 Antibodies 76 Antibodies 74 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Neutralization (Neut) 3 Antibodies
Intracellular Staining (ICS) 1 Antibodies 1 Antibodies 1 Antibodies
Immunoprecipitation (IP) 39 Antibodies 7 Antibodies 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 72 Antibodies 32 Antibodies 32 Antibodies
Immunohistochemistry (IHC) 101 Antibodies 30 Antibodies 29 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 4 Antibodies

General

Antigen Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibodies
Epitope pTyr980
(31), (30), (28), (26), (24), (21), (18), (14), (14), (13), (13), (13), (13), (13), (12), (8), (7), (6), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(429), (171), (169), (2), (2), (2), (2), (1), (1)
Host Rabbit
(295), (129), (2), (2)
Clonality
Polyclonal
Conjugate This IGF1R antibody is un-conjugated
(20), (19), (18), (16), (10), (9), (8), (8), (8), (8), (8), (8), (8), (8), (6)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(264), (107), (100), (88), (70), (58), (38), (29), (9), (8), (7), (4), (3), (3), (2), (1), (1), (1), (1)
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Product Details anti-IGF1R Antibody

Target Details IGF1R Application Details Handling Images
Specificity This antibdoy detects endogenous levels of IGF1R protein only when phosphorylated at Tyr980.
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity chromatography
Purity > 95 % by SDS-PAGE

Target Details IGF1R

Product Details anti-IGF1R Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD221 / IGF1R (IGF1R Antibody Abstract)
Background Receptor tyrosine kinases (RTKs) are transmembrane molecular scaffolds that influence cellular processes including the cell cycle, cell migration, cell metabolism, cell survival, proliferation and differentiation. Insulin-like growth factor-I receptor (IGF-IR) is an RTK that stimulates growth in many different cell types, blocks apoptosis, acts as an intermediate of many growth hormone responses and may stimulate the growth of some types of cancer. The IGF-IR cognate ligand insulin-like growth factor-I (IGF-I) promotes association of IGFIR with Shc, GRB2 and Sos 1, which initiates Ras and ERK kinase cascades, thereby modifying transcription factor activity, such as activation of the Elk transcription factors. The modular phosphotyrosine binding (PTB) domains of insulin receptor substrate (IRS)-1 and -2 can associate with active IGF-IR and initiate phosphatidylinositol 3-kinase-dependent downstream signals. The human IGFIR gene maps to chromosome 15q26.3 and encodes a 1,376 amino acid precursor protein that cleaves into alpha and beta subunits. The human IGF-IIR gene maps to chromosome 6q26 and encodes a 2,491 amino acid transmembrane protein.Synonyms: IGF-I receptor, IGF1 Receptor, Insulin-like growth factor 1 receptor
Molecular Weight approx. 95,155 kDa
Gene ID 3480
NCBI Accession NP_000866
UniProt P08069
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways RTK Signaling

Application Details

Product Details anti-IGF1R Antibody Target Details IGF1R Handling Images back to top
Application Notes Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-IGF1R Antibody Target Details IGF1R Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-IGF1R Antibody Target Details IGF1R Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-IGF1R antibody (Insulin-Like Growth Factor 1 Receptor) (pTyr980) (ABIN498849) Immunohistochemistry (IHC) analyzes of p-IGF1R antibody in paraffin-embedded h...