anti-Pig (Porcine) IGF1R antibody for Immunohistochemistry

Recommended IGF1R Antibody (supplied by: Log in to see )

Antigen
Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibodies
  • CD221
  • IGFIR
  • IGFR
  • JTK13
  • IGFIRC
  • IGFR1
  • IGF-1R
  • IGF1R
  • DKFZp469I0618
  • igf-1r
  • xIGF-1R
  • xIGFR
  • xigf1r
  • A330103N21Rik
  • D930020L01
  • hyft
  • igf-ir
  • insulin-like growth factor 1 receptor
  • insulin-like growth factor I receptor
  • IGF1R
  • Igf1r
  • igf1r
  • LOC780503
  • igf-ir
Epitope
Middle Region
39
37
35
30
25
23
20
16
15
15
15
15
14
14
12
9
9
8
7
5
5
5
4
4
4
4
4
4
4
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Sheep (Ovine), Zebrafish
496
249
237
18
14
10
7
6
5
5
5
4
2
1
1
Host
Rabbit
365
128
2
2
Clonality
Polyclonal
Conjugate
This IGF1R antibody is un-conjugated
22
18
16
15
9
9
8
8
8
8
8
8
8
8
8
7
6
4
Application
Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
310
116
104
103
88
84
47
41
8
6
6
4
3
2
2
1
1
1
1
1
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Catalog No. ABIN2792087
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN926846 IHC WB Rabbit Middle Region Log in to see Polyclonal

General

Antigen Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibodies
Epitope Middle Region
(39), (37), (35), (30), (25), (23), (20), (16), (15), (15), (15), (15), (14), (14), (12), (9), (9), (8), (7), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Sheep (Ovine), Zebrafish
(496), (249), (237), (18), (14), (10), (7), (6), (5), (5), (5), (4), (2), (1), (1)
Host Rabbit
(365), (128), (2), (2)
Clonality
Polyclonal
Conjugate This IGF1R antibody is un-conjugated
(22), (18), (16), (15), (9), (9), (8), (8), (8), (8), (8), (8), (8), (8), (8), (7), (6), (4)
Application Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB)
(310), (116), (104), (103), (88), (84), (47), (41), (8), (6), (6), (4), (3), (2), (2), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-IGF1R Antibody

Target Details IGF1R Application Details Handling References for anti-IGF1R antibody (ABIN2792087) Images
Sequence DRHSGHKAEN GPGPGVLVLR ASFDERQPYA HMNGGRKNER ALPLPQSSTC
Specificity Directed to the beta chain of IGF1R
Predicted Reactivity Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 92%, Sheep: 100%, Zebrafish: 100%
Characteristics This is a rabbit polyclonal antibody against IGF1R. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human IGF1R

Target Details IGF1R

Product Details anti-IGF1R Antibody Application Details Handling References for anti-IGF1R antibody (ABIN2792087) Images back to top
Antigen
Alternative Name IGF1R (IGF1R Antibody Abstract)
Background This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-140 DR007209.1 566-705 141-3559 X04434.1 136-3554 3560-4540 BC113610.1 3542-4522 4541-4921 DA486252.1 187-567 4922-5392 BX093045.1 248-718 5393-5768 CN414655.1 317-692 5769-6158 BM264223.1 185-574 6159-6580 BQ185364.1 187-608 6581-11242 AC069029.9 21278-25939 c
Alias Symbols: CD221, IGFIR, JTK13, MGC142170, MGC142172, MGC18216, IGFR
Protein Interaction Partner: KCNIP3, UBC, ESR1, PHB2, SHC1, FBXO6, SH2B1, Slc23a3, RPL11, HSP90AA1, GRB14, FFAR2, ARRB2, AMY2A, APP, RUVBL1, GNB2L1, ARRB1, YWHAG, TP53, NEDD4, MDM2, GRB10, SUMO1, CAMP, ERBB2, EGFR, KRT27, DOK5, DOK4, WISP2, EHD1, ARHGEF12, PIK3R3, VAV3, PRKD1, SOCS2,
Protein Size: 1367
Molecular Weight 71 kDa
Gene ID 3480
NCBI Accession NM_000875, NP_000866
UniProt P08069
Pathways RTK Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy

Application Details

Product Details anti-IGF1R Antibody Target Details IGF1R Handling References for anti-IGF1R antibody (ABIN2792087) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1367 AA

Restrictions For Research Use only

Handling

Product Details anti-IGF1R Antibody Target Details IGF1R Application Details References for anti-IGF1R antibody (ABIN2792087) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-IGF1R antibody (ABIN2792087)

Product Details anti-IGF1R Antibody Target Details IGF1R Application Details Handling Images back to top
Product cited in:

Kubota, Elalieh, Saless, Fong, Wang, Babey, Cheng, Bikle: "Insulin-like growth factor-1 receptor in mature osteoblasts is required for periosteal bone formation induced by reloading." in: Acta astronautica, Vol. 92, Issue 1, pp. 73-78, 2013

Background publications

Urano, Narusawa, Shiraki, Usui, Sasaki, Hosoi, Ouchi, Nakamura, Inoue: "Association of a single nucleotide polymorphism in the insulin-like growth factor-1 receptor gene with spinal disc degeneration in postmenopausal Japanese women." in: Spine, Vol. 33, Issue 11, pp. 1256-61, 2008

Images

Product Details anti-IGF1R Antibody Target Details IGF1R Application Details Handling References for anti-IGF1R antibody (ABIN2792087) back to top
Supplier Images
 image for anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (Middle Region) antibody (ABIN2792087) anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (Middle Region) antibody
Immunohistochemistry (IHC) image for anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (Middle Region) antibody (ABIN2792087) mouse skelatal muscle