anti-Rat (Rattus) IGF1R antibody for Enzyme Immunoassay

Recommended IGF1R Antibody (supplied by: Log in to see )

Antigen
Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibodies
  • CD221
  • IGFIR
  • IGFR
  • JTK13
  • IGFIRC
  • IGFR1
  • IGF-1R
  • IGF1R
  • DKFZp469I0618
  • igf-1r
  • xIGF-1R
  • xIGFR
  • xigf1r
  • A330103N21Rik
  • D930020L01
  • hyft
  • igf-ir
  • insulin-like growth factor 1 receptor
  • insulin-like growth factor I receptor
  • IGF1R
  • Igf1r
  • igf1r
  • LOC780503
  • igf-ir
Reactivity
Human, Mouse (Murine), Rat (Rattus)
496
249
237
18
15
11
7
7
6
5
5
5
2
2
1
Host
Rabbit
365
128
2
2
Clonality
Polyclonal
Conjugate
This IGF1R antibody is un-conjugated
22
18
16
15
9
9
8
8
8
8
8
8
8
8
8
7
6
4
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
310
117
104
103
88
84
48
41
8
6
5
4
3
2
2
1
1
1
1
1
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Catalog No. ABIN265476
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN318045 EIA IHC (p) IP WB Rabbit pTyr1161 Log in to see Polyclonal

General

Antigen Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(496), (249), (237), (18), (15), (11), (7), (7), (6), (5), (5), (5), (2), (2), (1)
Host Rabbit
(365), (128), (2), (2)
Clonality
Polyclonal
Conjugate This IGF1R antibody is un-conjugated
(22), (18), (16), (15), (9), (9), (8), (8), (8), (8), (8), (8), (8), (8), (8), (7), (6), (4)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(310), (117), (104), (103), (88), (84), (48), (41), (8), (6), (5), (4), (3), (2), (2), (1), (1), (1), (1), (1)
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Product Details anti-IGF1R Antibody

Target Details IGF1R Application Details Handling Images
Specificity This antibody detects endogenous levels of IGF-1R protein. (region surrounding Ile1160)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Purity > 95 % pure by SDS-PAGE

Target Details IGF1R

Product Details anti-IGF1R Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD221 / IGF1R (IGF1R Antibody Abstract)
Background Insulin-like growth factor-I receptor (IGF-IR) is an RTK that stimulates growth in many different cell types, blocks apoptosis, acts as an intermediate of many growth hormone responses and may stimulate the growth of some types of cancer. The IGF-IR cognate ligand insulin-like growth factor-I (IGF-I) promotes association of IGF-IR with Shc, GRB2 and Sos 1, which initiates Ras and ERK kinase cascades, thereby modifying transcription factor activity, such as activation of the Elk transcription factors. The modular phosphotyrosine binding (PTB) domains of insulin receptor substrate (IRS)-1 and -2 can associate with active IGF-IR and initiate phosphatidylinositol 3-kinase-dependent downstream signals.Synonyms: IGF-I receptor, IGF1 Receptor, Insulin-like growth factor 1 receptor
Molecular Weight approx. 95,155 kDa
Gene ID 3480
NCBI Accession NP_000866
UniProt P08069
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways RTK Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy

Application Details

Product Details anti-IGF1R Antibody Target Details IGF1R Handling Images back to top
Application Notes ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-IGF1R Antibody Target Details IGF1R Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice DO NOT FREEZE!
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

Images

Product Details anti-IGF1R Antibody Target Details IGF1R Application Details Handling back to top
Supplier Images
 image for anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) antibody (ABIN265476) anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) antibody