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anti-Zebrafish (Danio rerio) IGF1R antibody for Immunohistochemistry

Recommended IGF1R Antibody (supplied by: Log in to see )

Antigen
Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibodies
  • A330103N21Rik
  • CD221
  • D930020L01
  • DKFZp469I0618
  • hyft
  • IGF-1R
  • igf-1r
  • IGF1R
  • IGFIR
  • IGFIRC
  • IGFR
  • IGFR1
  • JTK13
  • xIGF-1R
  • xigf1r
  • xIGFR
Epitope
Middle Region
31
30
28
26
24
21
19
14
14
13
13
13
13
13
12
8
7
6
5
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Chicken, Cow (Bovine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
429
171
169
1
1
1
1
1
Host
Rabbit
295
129
2
2
Clonality
Polyclonal
Conjugate
This IGF1R antibody is un-conjugated
20
19
18
16
10
9
8
8
8
8
8
8
8
8
6
Application
Immunohistochemistry (IHC), Western Blotting (WB)
263
107
99
88
71
58
38
29
9
8
7
4
3
3
2
1
1
1
1
Supplier
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Catalog No. ABIN2792087
$ 289.00
Plus shipping costs $45.00

Top referenced anti-IGF1R antibody for Immunohistochemistry

Similar anti-IGF1R Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Chicken Cow (Bovine) Pig (Porcine) Xenopus laevis Zebrafish (Danio rerio)
Western Blotting (WB) 264 Antibodies 76 Antibodies 74 Antibodies 2 Antibodies 2 Antibodies 2 Antibodies 2 Antibodies 1 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Neutralization (Neut) 3 Antibodies
Intracellular Staining (ICS) 1 Antibodies 1 Antibodies 1 Antibodies
Immunoprecipitation (IP) 39 Antibodies 7 Antibodies 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 72 Antibodies 32 Antibodies 32 Antibodies

General

Antigen Insulin-Like Growth Factor 1 Receptor (IGF1R) Antibodies
Epitope Middle Region
(31), (30), (28), (26), (24), (21), (19), (14), (14), (13), (13), (13), (13), (13), (12), (8), (7), (6), (5), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Chicken, Cow (Bovine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
(429), (171), (169), (1), (1), (1), (1), (1)
Host Rabbit
(295), (129), (2), (2)
Clonality
Polyclonal
Conjugate This IGF1R antibody is un-conjugated
(20), (19), (18), (16), (10), (9), (8), (8), (8), (8), (8), (8), (8), (8), (6)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(263), (107), (99), (88), (71), (58), (38), (29), (9), (8), (7), (4), (3), (3), (2), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-IGF1R Antibody

Target Details IGF1R Application Details Handling References for anti-IGF1R Antibody (ABIN2792087) Images
Sequence DRHSGHKAEN GPGPGVLVLR ASFDERQPYA HMNGGRKNER ALPLPQSSTC
Specificity Directed to the beta chain of IGF1R
Predicted Reactivity African clawed frog : 100 %, Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Horse : 100 %, Human : 100 %, Pig : 100 %, Sheep : 100 %, Zebrafish : 100 %, Mouse : 90 %, Rat : 90 %
Characteristics This is a rabbit polyclonal antibody against IGF1R. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human IGF1R

Target Details IGF1R

Product Details anti-IGF1R Antibody Application Details Handling References for anti-IGF1R Antibody (ABIN2792087) Images back to top
Antigen
Alternative Name IGF1R (IGF1R Antibody Abstract)
Background This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.
Molecular Weight 71 kDa
Gene ID 3480
NCBI Accession NP_000866, NM_000875
UniProt P08069
Pathways RTK Signaling

Application Details

Product Details anti-IGF1R Antibody Target Details IGF1R Handling References for anti-IGF1R Antibody (ABIN2792087) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 1367 AA

Restrictions For Research Use only

Handling

Product Details anti-IGF1R Antibody Target Details IGF1R Application Details References for anti-IGF1R Antibody (ABIN2792087) Images back to top
Format Liquid
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment For short term use, store at 2-8 °C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-IGF1R Antibody (ABIN2792087)

Product Details anti-IGF1R Antibody Target Details IGF1R Application Details Handling Images back to top
Product cited in:

Kubota, Elalieh, Saless, Fong, Wang, Babey, Cheng, Bikle: "Insulin-like growth factor-1 receptor in mature osteoblasts is required for periosteal bone formation induced by reloading." in: Acta astronautica, Vol. 92, Issue 1, pp. 73-78, 2013

Background publications

Urano, Narusawa, Shiraki, Usui, Sasaki, Hosoi, Ouchi, Nakamura, Inoue: "Association of a single nucleotide polymorphism in the insulin-like growth factor-1 receptor gene with spinal disc degeneration in postmenopausal Japanese women." in: Spine, Vol. 33, Issue 11, pp. 1256-61, 2008

Images

Product Details anti-IGF1R Antibody Target Details IGF1R Application Details Handling References for anti-IGF1R Antibody (ABIN2792087) back to top
Supplier Images
Western Blotting (WB) image for anti-IGF1R antibody (Insulin-Like Growth Factor 1 Receptor) (Middle Region) (ABIN2792087) WB Suggested Anti-IGF1R Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
 image for anti-IGF1R antibody (Insulin-Like Growth Factor 1 Receptor) (Middle Region) (ABIN2792087) anti-Insulin-Like Growth Factor 1 Receptor (IGF1R) (Middle Region) antibody (Image 2)
Immunohistochemistry (IHC) image for anti-IGF1R antibody (Insulin-Like Growth Factor 1 Receptor) (Middle Region) (ABIN2792087) mouse skelatal muscle