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anti-Mouse (Murine) IL34 antibody for Flow Cytometry

Recommended IL34 Antibody (supplied by: Log in to see )

Antigen
Interleukin 34 (IL34) Antibodies
  • C16orf77
  • IL-34
  • 2010004A03Rik
  • AI593503
  • C18H16ORF77
  • interleukin 34
  • interleukin-34-like
  • IL34
  • Il34
  • LOC100347811
  • LOC100737468
Reactivity
Mouse (Murine)
79
31
22
Host
Rat
54
34
7
2
1
Clonality
Monoclonal
Conjugate
This IL34 antibody is un-conjugated
13
4
3
3
2
2
1
1
1
1
1
1
1
Application
Blocking Reagent (BR), Flow Cytometry (FACS)
75
62
26
9
8
7
4
3
2
2
2
1
1
Supplier
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Catalog No. ABIN2665836
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2660791 BR FACS IF IP IHC WB Biotin Goat Ig Fraction Log in to see Polyclonal 5
1 ABIN2665167 FACS Rat IgG2c Log in to see C051-77 5
1 ABIN2665835 BR FACS Rat IgG1 kappa Log in to see C054-35 5

Top referenced anti-IL34 antibody for Flow Cytometry

Similar anti-IL34 Antibodies

Application / Reactivity Mouse (Murine)
Blocking Reagent (BR) 3 Antibodies
ELISA 19 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 4 Antibodies
Immunocytochemistry (ICC) 2 Antibodies
Immunofluorescence (IF) 1 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies
Immunohistochemistry (IHC) 4 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 1 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Western Blotting (WB) 29 Antibodies

General

Antigen Interleukin 34 (IL34) Antibodies
Reactivity Mouse (Murine)
(79), (31), (22)
Host Rat
(54), (34), (7), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL34 antibody is un-conjugated
(13), (4), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Blocking Reagent (BR), Flow Cytometry (FACS)
(75), (62), (26), (9), (8), (7), (4), (3), (2), (2), (2), (1), (1)
Pubmed 5 references available
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Product Details anti-IL34 Antibody

Target Details IL34 Application Details Handling References for anti-IL34 Antibody (ABIN2665836) Images
Brand LEAF™
Purification The LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
Sterility 0.2 μm filtered
Endotoxin Level

Endotoxin level is <0.1 EU/μg of the protein (<0.01 ng/μg of the protein) as determined by the LAL test.

Clone C054-35
Isotype IgG1 kappa

Target Details IL34

Product Details anti-IL34 Antibody Application Details Handling References for anti-IL34 Antibody (ABIN2665836) Images back to top
Antigen
Alternative Name IL-34 (IL34 Antibody Abstract)
Background IL-34 is a homodimeric glycoprotein which contains 241 amino acids. IL-34 is expressed in the heart, brain, lung, liver, kidney, thymus, spleen, and other organs. It specifically binds to CD115/M-CSF receptor (CSF-1 receptor or c-Fms) and activates ERK1/2 phosphorylation. The function of IL-34 overlaps with CSF-1 to regulate myeloid lineage differentiation, proliferation, and survival. Elevated levels of IL-34 are seen in the plasma of rheumatoid arthritis patients, but can be decreased in response to therapy. IL-34 levels are also increased in the serum of cancer patients and are associated with poor prognosis. Mouse IL-34 shares 71 % sequence identity with human IL-34 on the amino acid level.
Pathways RTK Signaling

Application Details

Product Details anti-IL34 Antibody Target Details IL34 Handling References for anti-IL34 Antibody (ABIN2665836) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IL34 Antibody Target Details IL34 Application Details References for anti-IL34 Antibody (ABIN2665836) Images back to top
Concentration 1.0 mg/mL
Preservative Azide free
Handling Advice This LEAF™ solution contains no preservative, handle under aseptic conditions
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-IL34 Antibody (ABIN2665836)

Product Details anti-IL34 Antibody Target Details IL34 Application Details Handling Images back to top
Background publications

Eda, Shimada, Beidler, Monahan: "Proinflammatory cytokines, IL-1β and TNF-α, induce expression of interleukin-34 mRNA via JNK- and p44/42 MAPK-NF-κB pathway but not p38 pathway in osteoblasts." in: Rheumatology international, Vol. 31, Issue 11, pp. 1525-30, 2011

Chihara, Suzu, Hassan, Chutiwitoonchai, Hiyoshi, Motoyoshi, Kimura, Okada: "IL-34 and M-CSF share the receptor Fms but are not identical in biological activity and signal activation." in: Cell death and differentiation, Vol. 17, Issue 12, pp. 1917-27, 2010

Covaleda, Fuller, Payne: "EIAV S2 enhances pro-inflammatory cytokine and chemokine response in infected macrophages." in: Virology, Vol. 397, Issue 1, pp. 217-23, 2010

Wei, Nandi, Chitu, Yeung, Yu, Huang, Williams, Lin, Stanley: "Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells." in: Journal of leukocyte biology, Vol. 88, Issue 3, pp. 495-505, 2010

Lin, Lee, Hestir, Leo, Huang, Bosch, Halenbeck, Wu, Zhou, Behrens, Hollenbaugh, Linnemann, Qin, Wong, Chu, Doberstein, Williams: "Discovery of a cytokine and its receptor by functional screening of the extracellular proteome." in: Science (New York, N.Y.), Vol. 320, Issue 5877, pp. 807-11, 2008

Images

Product Details anti-IL34 Antibody Target Details IL34 Application Details Handling References for anti-IL34 Antibody (ABIN2665836) back to top
Supplier Images
ELISA image for anti-IL34 antibody (Interleukin 34) (ABIN2665836) anti-Interleukin 34 (IL34) antibody