anti-Mouse (Murine) IL34 antibody for Immunoprecipitation

Recommended IL34 Antibody (supplied by: Log in to see )

Antigen
Interleukin 34 (IL34) Antibodies
  • C16orf77
  • IL-34
  • 2010004A03Rik
  • AI593503
  • C18H16ORF77
  • interleukin 34
  • interleukin-34-like
  • IL34
  • Il34
  • LOC100347811
  • LOC100737468
Reactivity
Mouse (Murine)
114
31
22
1
1
Host
Rat
62
61
7
2
1
Clonality
Monoclonal
Conjugate
This IL34 antibody is un-conjugated
15
5
5
4
4
4
4
3
3
3
3
3
2
1
1
1
1
1
1
1
Application
Immunoprecipitation (IP)
76
75
44
11
11
10
4
3
3
2
2
2
2
2
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

Submit your validation data for this product and get a full refund. I want to validate this product

Learn more

Available images

Catalog No. ABIN2665167
Contact our Customer Service for availability and price in your country.
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN1175348 ICC IHC IP WB Rabbit IgG AA 21-235 Log in to see Polyclonal

General

Antigen Interleukin 34 (IL34) Antibodies
Reactivity Mouse (Murine)
(114), (31), (22), (1), (1)
Host Rat
(62), (61), (7), (2), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IL34 antibody is un-conjugated
(15), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1)
Application Immunoprecipitation (IP)
(76), (75), (44), (11), (11), (10), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1)
Pubmed 5 references available
Supplier Log in to see

Product Details anti-IL34 Antibody

Target Details IL34 Application Details Handling References for anti-IL34 antibody (ABIN2665167) Images
Purification The antibody was purified by affinity chromatography.
Clone C051-77
Isotype IgG2c

Target Details IL34

Product Details anti-IL34 Antibody Application Details Handling References for anti-IL34 antibody (ABIN2665167) Images back to top
Antigen
Alternative Name IL-34 (IL34 Antibody Abstract)
Background IL-34 is a glycoprotein that plays important roles in the proliferation, survival, and differentiation of monocytes and macrophages. IL-34 is expressed in the heart, brain, lung, liver, kidney, thymus, spleen, and other organs. It specifically binds to CD115/M-CSF receptor (CSF-1 receptor or c-Fms) and activates ERK1/2 phosphorylation. The function of IL-34 overlaps with CSF-1 to regulate myeloid lineage development. IL-34 also promotes inflammatory processes and regulates osteoclast proliferation, differentiation, and bone reabsorption.
Pathways RTK Signaling

Application Details

Product Details anti-IL34 Antibody Target Details IL34 Handling References for anti-IL34 antibody (ABIN2665167) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-IL34 Antibody Target Details IL34 Application Details References for anti-IL34 antibody (ABIN2665167) Images back to top
Concentration 0.5 mg/mL
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-IL34 antibody (ABIN2665167)

Product Details anti-IL34 Antibody Target Details IL34 Application Details Handling Images back to top
Background publications

Eda, Shimada, Beidler, Monahan: "Proinflammatory cytokines, IL-1β and TNF-α, induce expression of interleukin-34 mRNA via JNK- and p44/42 MAPK-NF-κB pathway but not p38 pathway in osteoblasts." in: Rheumatology international, Vol. 31, Issue 11, pp. 1525-30, 2011

Covaleda, Fuller, Payne: "EIAV S2 enhances pro-inflammatory cytokine and chemokine response in infected macrophages." in: Virology, Vol. 397, Issue 1, pp. 217-23, 2010

Wei, Nandi, Chitu, Yeung, Yu, Huang, Williams, Lin, Stanley: "Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells." in: Journal of leukocyte biology, Vol. 88, Issue 3, pp. 495-505, 2010

Chihara, Suzu, Hassan, Chutiwitoonchai, Hiyoshi, Motoyoshi, Kimura, Okada: "IL-34 and M-CSF share the receptor Fms but are not identical in biological activity and signal activation." in: Cell death and differentiation, Vol. 17, Issue 12, pp. 1917-27, 2010

Lin, Lee, Hestir, Leo, Huang, Bosch, Halenbeck, Wu, Zhou, Behrens, Hollenbaugh, Linnemann, Qin, Wong, Chu, Doberstein, Williams: "Discovery of a cytokine and its receptor by functional screening of the extracellular proteome." in: Science (New York, N.Y.), Vol. 320, Issue 5877, pp. 807-11, 2008

Images

Product Details anti-IL34 Antibody Target Details IL34 Application Details Handling References for anti-IL34 antibody (ABIN2665167) back to top
Supplier Images
Western Blotting (WB) image for anti-Interleukin 34 (IL34) antibody (ABIN2665167) anti-Interleukin 34 (IL34) antibody