Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Show all synonyms
Select your origin of interest
Human IL34 Protein expressed in CHO Cells - ABIN2666711
Chen, Buki, Vääräniemi, Gu, Väänänen: The critical role of IL-34 in osteoclastogenesis. in PLoS ONE 2011
Show all 6 references for ABIN2666711
Mouse (Murine) IL34 Protein expressed in CHO Cells - ABIN2666972
Lin, Lee, Hestir, Leo, Huang, Bosch, Halenbeck, Wu, Zhou, Behrens, Hollenbaugh, Linnemann, Qin, Wong, Chu, Doberstein, Williams: Discovery of a cytokine and its receptor by functional screening of the extracellular proteome. in Science (New York, N.Y.) 2008
Show all 5 references for ABIN2666972
Human IL34 Protein expressed in CHO Cells - ABIN2666979
Chihara, Suzu, Hassan, Chutiwitoonchai, Hiyoshi, Motoyoshi, Kimura, Okada: IL-34 and M-CSF share the receptor Fms but are not identical in biological activity and signal activation. in Cell death and differentiation 2010
Show all 5 references for ABIN2666979
Mouse (Murine) IL34 Protein expressed in CHO Cells - ABIN2666664
Covaleda, Fuller, Payne: EIAV S2 enhances pro-inflammatory cytokine and chemokine response in infected macrophages. in Virology 2010
Show all 4 references for ABIN2666664
Human IL34 Protein expressed in Escherichia coli (E. coli) - ABIN1098782
Wang, Szretter, Vermi, Gilfillan, Rossini, Cella, Barrow, Diamond, Colonna: IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia. in Nature immunology 2012
Show all 2 references for ABIN1098782
The receiver operating characteristic (ROC) curve analysis has shown that IL-34 has more discriminatory power than C-reactive protein (CRP (show CRP Proteins)) for the risk of diabetic complications. The cut-off value for IL-34 was established as 91.2 pg/mL. The gist of our research was identification of IL-34 as an additional potential inflammatory biomarker for the prediction of the risk of vascular diabetic complications.
miR (show MLXIP Proteins)-28-5p-IL-34-macrophage feedback loop modulates hepatocellular carcinoma metastasis
findings demonstrated that M-CSF (show CSF1 Proteins) binds to IL-34; molecular docking studies predicted the formation of a heteromeric M-CSF (show CSF1 Proteins)/IL-34 cytokine
These results suggest that IL-34, a novel osteoclastogenic cytokine, plays a role in rheumatoid arthritis-associated joint damage and is a potential biomarker for predicting subsequent radiographic progression in patients with RA.
IL-34 is expressed by human FOXP3 (show FOXP3 Proteins)+CD45RCloCD8+ and CD4 (show CD4 Proteins)+ Tregs and markedly inhibited alloreactive immune responses.
This paper provides evidence of alternative binding of IL-34 to chondroitin sulphates and syndecan-1 (show SDC1 Proteins) at the cell surface that modulates M-CSFR (show CSF1R Proteins) activation.
In vitro and in vivo experiments indicate that IL-34 expression is regulated by TNF-a (show TNF Proteins) and IL-1b (show IL1B Proteins) and that its overexpression is associated with an increase in osteosarcoma growth and metastasis.
the expression pattern of IL-34 in ileum and colon and suggest IL-34 as a new modulator of inflammation in inflammatory bowel disease
IL-34 is up-regulated in inflammatory bowel disease and suggest a role for this cytokine in sustaining the inflammatory responses in this disease
IL-34 is induced by IL-22 (show IL22 Proteins) in the inflammatory cascade in response to IAV infection.
study concludes that Langerhans cells require IL-34 when residing in fully differentiated and anatomically intact skin epidermis, but rely on neutrophil-derived CSF1 (show CSF1 Proteins) during inflammation
constitutive IL-34 expressed by skin keratinocytes might suppress resident macrophage responses to C. albicans colonisation by maintaining low levels TLR2 and Dectin-1 (show CLEC7A Proteins) expression by macrophages.
IL-34 protected blood-brain barrier integrity by restored expression levels of tight junction proteins, which were downregulated by pro-inflammatory cytokines.
IL-34-dependent, Mo-mediated, CSF-1 (show CSF1 Proteins) nonredundant mechanisms promote persistent ischemia-incited AKI that worsens subsequent CKD.
Tumor necrosis factor-alpha (show TNF Proteins) induces IL-34 expression via NF-kappaB (show NFKB1 Proteins) in MC3T3-E1 osteoblastic cells.
These findings suggest that TGF-beta (show TGFB1 Proteins) produced by IL-34-treated microglia is a negative regulator of microglial proliferation and enhances the neuroprotective property of microglia.
Differentiated signaling between IL-34 and CSF-1 (show CSF1 Proteins) is likely achieved by the relative thermodynamic independence of IL-34 versus negative cooperativity of CSF-1 (show CSF1 Proteins) at the CSF-1 receptor (show CSF1R Proteins) recognition sites.
IL-34 as a nonredundant cytokine for the development of Langerhans cells during embryogenesis as well as for their homeostasis in the adult skin.
Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R\; MIM 164770) (Lin et al., 2008