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Browse our IL34 Proteins (IL34)

Full name:
Interleukin 34 Proteins (IL34)
On www.antibodies-online.com are 31 Interleukin 34 (IL34) Proteins from 13 different suppliers available. Additionally we are shipping IL34 Antibodies (98) and IL34 Kits (54) and many more products for this protein. A total of 191 IL34 products are currently listed.
Synonyms:
2010004A03Rik, AI593503, C16orf77, C18H16ORF77, IL-34
list all proteins Gene Name GeneID UniProt
IL34 146433 Q6ZMJ4
IL34 76527 Q8R1R4
IL34 498951 Q4KM46

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IL34 Proteins (IL34) by Origin

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Top referenced IL34 Proteins

  1. Human IL34 Protein expressed in CHO Cells - ABIN2666711 : Chen, Buki, Vääräniemi, Gu, Väänänen: The critical role of IL-34 in osteoclastogenesis. in PLoS ONE 2011 (PubMed)
    Show all 6 references for ABIN2666711

  2. Mouse (Murine) IL34 Protein expressed in CHO Cells - ABIN2666972 : Lin, Lee, Hestir, Leo, Huang, Bosch, Halenbeck, Wu, Zhou, Behrens, Hollenbaugh, Linnemann, Qin, Wong, Chu, Doberstein, Williams: Discovery of a cytokine and its receptor by functional screening of the extracellular proteome. in Science (New York, N.Y.) 2008 (PubMed)
    Show all 5 references for ABIN2666972

  3. Human IL34 Protein expressed in CHO Cells - ABIN2666979 : Chihara, Suzu, Hassan, Chutiwitoonchai, Hiyoshi, Motoyoshi, Kimura, Okada: IL-34 and M-CSF share the receptor Fms but are not identical in biological activity and signal activation. in Cell death and differentiation 2010 (PubMed)
    Show all 5 references for ABIN2666979

  4. Mouse (Murine) IL34 Protein expressed in CHO Cells - ABIN2666664 : Covaleda, Fuller, Payne: EIAV S2 enhances pro-inflammatory cytokine and chemokine response in infected macrophages. in Virology 2010 (PubMed)
    Show all 4 references for ABIN2666664

  5. Human IL34 Protein expressed in Escherichia coli (E. coli) - ABIN1098782 : Wang, Szretter, Vermi, Gilfillan, Rossini, Cella, Barrow, Diamond, Colonna: IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia. in Nature immunology 2012 (PubMed)
    Show all 2 references for ABIN1098782

More Proteins for IL34 Interaction Partners

Human Interleukin 34 (IL34) interaction partners

  1. miR (show MLXIP Proteins)-28-5p-IL-34-macrophage feedback loop modulates hepatocellular carcinoma metastasis

  2. findings demonstrated that M-CSF (show CSF1 Proteins) binds to IL-34; molecular docking studies predicted the formation of a heteromeric M-CSF (show CSF1 Proteins)/IL-34 cytokine

  3. These results suggest that IL-34, a novel osteoclastogenic cytokine, plays a role in rheumatoid arthritis-associated joint damage and is a potential biomarker for predicting subsequent radiographic progression in patients with RA.

  4. IL-34 is expressed by human FOXP3 (show FOXP3 Proteins)+CD45RCloCD8+ and CD4 (show CD4 Proteins)+ Tregs and markedly inhibited alloreactive immune responses.

  5. This paper provides evidence of alternative binding of IL-34 to chondroitin sulphates and syndecan-1 (show SDC1 Proteins) at the cell surface that modulates M-CSFR (show CSF1R Proteins) activation.

  6. In vitro and in vivo experiments indicate that IL-34 expression is regulated by TNF-a (show TNF Proteins) and IL-1b (show IL1B Proteins) and that its overexpression is associated with an increase in osteosarcoma growth and metastasis.

  7. the expression pattern of IL-34 in ileum and colon and suggest IL-34 as a new modulator of inflammation in inflammatory bowel disease

  8. IL-34 is up-regulated in inflammatory bowel disease and suggest a role for this cytokine in sustaining the inflammatory responses in this disease

  9. IL-34 is induced by IL-22 (show IL22 Proteins) in the inflammatory cascade in response to IAV infection.

  10. IL-34 expression in human gingival fibroblasts, stimulated by TNF-alpha (show TNF Proteins) and IL-1beta (show IL1B Proteins)

Mouse (Murine) Interleukin 34 (IL34) interaction partners

  1. study concludes that Langerhans cells require IL-34 when residing in fully differentiated and anatomically intact skin epidermis, but rely on neutrophil-derived CSF1 (show CSF1 Proteins) during inflammation

  2. constitutive IL-34 expressed by skin keratinocytes might suppress resident macrophage responses to C. albicans colonisation by maintaining low levels TLR2 and Dectin-1 (show CLEC7A Proteins) expression by macrophages.

  3. IL-34 protected blood-brain barrier integrity by restored expression levels of tight junction proteins, which were downregulated by pro-inflammatory cytokines.

  4. IL-34-dependent, Mo-mediated, CSF-1 (show CSF1 Proteins) nonredundant mechanisms promote persistent ischemia-incited AKI that worsens subsequent CKD.

  5. In vitro and in vivo experiments indicate that IL-34 expression is regulated by TNF-a (show TNF Proteins) and IL-1b (show IL1B Proteins) and that its overexpression is associated with an increase in osteosarcoma growth and metastasis.

  6. the expression pattern of IL-34 in ileum and colon and suggest IL-34 as a new modulator of inflammation in inflammatory bowel disease

  7. Tumor necrosis factor-alpha (show TNF Proteins) induces IL-34 expression via NF-kappaB (show NFKB1 Proteins) in MC3T3-E1 osteoblastic cells.

  8. These findings suggest that TGF-beta (show TGFB1 Proteins) produced by IL-34-treated microglia is a negative regulator of microglial proliferation and enhances the neuroprotective property of microglia.

  9. Differentiated signaling between IL-34 and CSF-1 (show CSF1 Proteins) is likely achieved by the relative thermodynamic independence of IL-34 versus negative cooperativity of CSF-1 (show CSF1 Proteins) at the CSF-1 receptor (show CSF1R Proteins) recognition sites.

  10. IL-34 as a nonredundant cytokine for the development of Langerhans cells during embryogenesis as well as for their homeostasis in the adult skin.

IL34 Protein Profile

Protein Summary

Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R\; MIM 164770) (Lin et al., 2008

Alternative names and synonyms associated with IL34

  • interleukin 34 (IL34)
  • interleukin 34 (Il34)
  • interleukin 34 (LOC100347811)
  • interleukin-34-like (LOC100737468)
  • 2010004A03Rik protein
  • AI593503 protein
  • C16orf77 protein
  • C18H16ORF77 protein
  • IL-34 protein

Protein level used designations for Interleukin 34 Proteins (IL34)

interleukin 34 , interleukin-34 , IL-34

GENE ID SPECIES
454217 Pan troglodytes
100499188 Taeniopygia guttata
146433 Homo sapiens
76527 Mus musculus
498951 Rattus norvegicus
100347811 Oryctolagus cuniculus
100723831 Cavia porcellus
508292 Bos taurus
610536 Canis lupus familiaris
100858424 Gallus gallus
101113261 Ovis aries
100737468 Sus scrofa
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