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anti-Human LTK antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended LTK Antibody (supplied by: Log in to see )

Antigen
Leukocyte Receptor tyrosine Kinase (LTK) Antibodies
  • ALK
  • LTK
  • si:dz107o16.1
  • TYK1
Epitope
AA 800-864
23
19
15
6
6
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
62
25
2
1
Host
Rabbit
79
2
1
Clonality
Polyclonal
Conjugate
This LTK antibody is un-conjugated
5
5
5
4
4
4
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
64
40
11
7
5
1
1
Supplier
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Catalog No. ABIN372432
$ 500.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089475926 ABIN292876 IHC (p) WB Rabbit IgG AA 800-864 Log in to see Polyclonal
0.00089475926 ABIN1830396 IHC (p) WB Sheep IgG AA 10-424 Log in to see Polyclonal
0.00089475926 ABIN1736600 IHC (p) WB Rabbit IgG AA 800-864 Log in to see Polyclonal
0.00089475926 ABIN1700054 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
0.00089475926 ABIN1711071 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
0.00089475926 ABIN1713556 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.00089475926 ABIN2770941 IHC (p) WB Rabbit IgG AA 800-864 Log in to see Polyclonal

Similar anti-LTK Antibodies

Application / Reactivity Human
ELISA 24 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Immunofluorescence (IF) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 5 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 8 Antibodies
Western Blotting (WB) 51 Antibodies

General

Antigen Leukocyte Receptor tyrosine Kinase (LTK) Antibodies
Epitope AA 800-864
(23), (19), (15), (6), (6), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(62), (25), (2), (1)
Host Rabbit
(79), (2), (1)
Clonality
Polyclonal
Conjugate This LTK antibody is un-conjugated
(5), (5), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(64), (40), (11), (7), (5), (1), (1)
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Product Details anti-LTK Antibody

Target Details LTK Application Details Handling Images
Specificity This antibody recognizes Leukocyte Protein Tyrosine Kinase LTK.
Cross-Reactivity (Details) Species reactivity (tested):Human.
Purification Protein G Chromatography.
Immunogen Synthetic peptide corresponding to a portion of amino acids 800-864 of Human LTK.
Isotype IgG

Target Details LTK

Product Details anti-LTK Antibody Application Details Handling Images back to top
Antigen
Alternative Name LTK / TYK1 (LTK Antibody Abstract)
Background Leukocyte tyrosine kinase (LTK) is a receptor-type protein tyrosine kinase, belonging to the insulin receptor superfamily, and is mainly expressed in B lymphocyte precursors and neuronal tissues. LTK utilizes insulin receptor substrate-1 (IRS-1) and Shc as major two substrates and possesses two NPXY motifs for them separately, tyrosine 485 of one NPXY motif at the juxtamembrane domain for IRS-1 and tyrosine 862 of another NPXY motif at the carboxyl-terminal domain for Shc. It has also been shown that p85 subunit of PI3 kinase directly binds to tyrosine 753 of LTK, which is located within a YXXM motif. Tyrosine 485 and 753 are responsible for IRS-1 and PI3K mediated survival effects of LTK, respectively.Synonyms: Leukocyte tyrosine kinase receptor, Protein tyrosine kinase 1
Gene ID 4058
NCBI Accession NP_002335
UniProt P29376
Pathways RTK Signaling

Application Details

Product Details anti-LTK Antibody Target Details LTK Handling Images back to top
Application Notes Immunohistochemistry on Paraffin Sections: 10 μg/mL. Western blot: 0.5-2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-LTK Antibody Target Details LTK Application Details Images back to top
Concentration 0.5 mg/mL
Buffer PBS containing 0.2 % Gelatin as stabilizer and 0.05 % Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Images

Product Details anti-LTK Antibody Target Details LTK Application Details Handling back to top
Supplier Images
 image for anti-LTK antibody (Leukocyte Receptor tyrosine Kinase) (AA 800-864) (ABIN372432) anti-Leukocyte Receptor tyrosine Kinase (LTK) (AA 800-864) antibody