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anti-Human MCK10 antibody for Enzyme Immunoassay

Recommended MCK10 Antibody (supplied by: Log in to see )

Antigen
Discoidin Domain Receptor Family, Member 1 (DDR1) Antibodies
  • 6030432F18
  • AI323681
  • CAK
  • Cak
  • CD167
  • CD167a
  • DDR
  • DDR1
  • Drd1
  • EDDR1
  • HGK2
  • MCK10
  • Nep
  • NEP
  • NTRK4
  • PTK3
  • PTK3A
  • PTK3D
  • RTK6
  • TRKE
Epitope
Middle Region
5
2
1
1
1
1
Reactivity
Human
16
6
6
Host
Rabbit
11
5
Clonality
Polyclonal
Conjugate
This MCK10 antibody is un-conjugated
2
1
1
Application
Enzyme Immunoassay (EIA), Western Blotting (WB)
9
5
4
3
2
1
1
1
Supplier
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Catalog No. ABIN359548
$ 401.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.000887034 ABIN359897 EIA FACS IHC (p) WB Rabbit Ig N-Term Log in to see Polyclonal 5
0.000887034 ABIN359899 EIA IHC (p) WB Rabbit Ig Log in to see Polyclonal 5
0.000887034 ABIN614409 EIA IHC (p) WB Mouse IgG1 AA 602-681 Log in to see 2G4E12

Top referenced anti-MCK10 antibody for Enzyme Immunoassay

Similar anti-MCK10 Antibodies

Application / Reactivity Human
ELISA 2 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Flow Cytometry (FACS) 4 Antibodies
Immunofluorescence (IF) 1 Antibodies
Immunohistochemistry (IHC) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 5 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Western Blotting (WB) 10 Antibodies

General

Antigen Discoidin Domain Receptor Family, Member 1 (DDR1) Antibodies
Epitope Middle Region
(5), (2), (1), (1), (1), (1)
Reactivity Human
(16), (6), (6)
Host Rabbit
(11), (5)
Clonality
Polyclonal
Conjugate This MCK10 antibody is un-conjugated
(2), (1), (1)
Application Enzyme Immunoassay (EIA), Western Blotting (WB)
(9), (5), (4), (3), (2), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-MCK10 Antibody

Target Details MCK10 Application Details Handling References for anti-MCK10 Antibody (ABIN359548) Images
Specificity This antibody reacts to DDR1.
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide at the Center of human DDR1.
Isotype Ig

Target Details MCK10

Product Details anti-MCK10 Antibody Application Details Handling References for anti-MCK10 Antibody (ABIN359548) Images back to top
Antigen
Alternative Name CD167a / DDR1 (DDR1 Antibody Abstract)
Background Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. DDR1 is an RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. It belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis show that expression of DDR1 is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain.Synonyms: CAK, CD167 antigen-like family member A, EDDR1, Epithelial discoidin domain receptor 1, Epithelial discoidin domain-containing receptor 1, MCK10, NEP, NTRK4, PTK3A, RTK6, TRKE, Tyrosine kinase DDR-1
Gene ID 780, 9606
UniProt Q08345
Pathways RTK Signaling

Application Details

Product Details anti-MCK10 Antibody Target Details MCK10 Handling References for anti-MCK10 Antibody (ABIN359548) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-MCK10 Antibody Target Details MCK10 Application Details References for anti-MCK10 Antibody (ABIN359548) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-MCK10 Antibody (ABIN359548)

Product Details anti-MCK10 Antibody Target Details MCK10 Application Details Handling Images back to top
Background publications

Sakuma, Saya, Tada, Nakao, Fujiwara, Roth, Sawamura, Shinohe, Abe: "Receptor protein tyrosine kinase DDR is up-regulated by p53 protein." in: FEBS letters, Vol. 398, Issue 2-3, pp. 165-9, 1997

Johnson, Edman, Rutter: "A receptor tyrosine kinase found in breast carcinoma cells has an extracellular discoidin I-like domain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 12, pp. 5677-81, 1993

Images

Product Details anti-MCK10 Antibody Target Details MCK10 Application Details Handling References for anti-MCK10 Antibody (ABIN359548) back to top
Supplier Images
Western Blotting (WB) image for anti-MCK10 antibody (Discoidin Domain Receptor Family, Member 1) (Middle Region) (ABIN359548) Western blot analysis of DDR1 (arrow) using rabbit polyclonal DDR1 Antibody