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anti-Human MCK10 antibody for Flow Cytometry

Recommended MCK10 Antibody (supplied by: Log in to see )

Antigen
Discoidin Domain Receptor Family, Member 1 (DDR1) Antibodies
  • 6030432F18
  • AI323681
  • CAK
  • Cak
  • CD167
  • CD167a
  • DDR
  • DDR1
  • Drd1
  • EDDR1
  • HGK2
  • MCK10
  • Nep
  • NEP
  • NTRK4
  • PTK3
  • PTK3A
  • PTK3D
  • RTK6
  • TRKE
Reactivity
Human
16
6
6
Host
Mouse
12
4
Clonality
Monoclonal
Conjugate
This MCK10 antibody is conjugated to PE
1
1
1
Application
Flow Cytometry (FACS)
10
5
4
3
2
1
1
1
Supplier
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Catalog No. ABIN2663088
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.3068567 ABIN2664284 FACS Mouse IgG3 kappa Log in to see 51D6 4
0.0010666476 ABIN359897 EIA FACS IHC (p) WB Rabbit Ig N-Term Log in to see Polyclonal 5
0.0010666476 ABIN2663089 FACS PE Mouse IgG3 kappa Log in to see 51D6 5

Top referenced anti-MCK10 antibody for Flow Cytometry

Similar anti-MCK10 Antibodies

Application / Reactivity Human
ELISA 2 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Flow Cytometry (FACS) 4 Antibodies
Immunofluorescence (IF) 1 Antibodies
Immunohistochemistry (IHC) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 5 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Western Blotting (WB) 10 Antibodies

General

Antigen Discoidin Domain Receptor Family, Member 1 (DDR1) Antibodies
Reactivity Human
(16), (6), (6)
Host Mouse
(12), (4)
Clonality (Clone)
Monoclonal   ( )
Conjugate This MCK10 antibody is conjugated to PE
(1), (1), (1)
Application Flow Cytometry (FACS)
(10), (5), (4), (3), (2), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-MCK10 Antibody

Target Details MCK10 Application Details Handling References for anti-MCK10 Antibody (ABIN2663088) Images
Characteristics The 51D6 monclonal antibody recognizes human CD167a also known as discoidin domain receptor, DDR1, neuroepithelial tyrosine kinase, epithelial-specific receptor kinase, tyrosine kinase receptor E (trkE), cell adhesion kinase (CAK), PTK3, and RTK6. CD167a is a membrane type II receptor kinase, containing a factor VIII-like domain. At least five isoforms are generated through alternative splicing of the kinase domain of human DDR1 gene. These isoforms are named wtih suffixes a to e. CD167a is expressed on epithelial cells, keratinocytes, leukocytes, monocytes and has been reported to be overexpressed in some breast carcinomas. CD167a expression can be upregulated by p53. CD167a has been reported to interact with a variety of proteins including collagen type II alpha 1, collagen type III alpha 1, collagen type V alpha 2, collagen type XI alpha 1, phospholipase gamma 1, SHC, and the lipid-anchored docking protein FRS2. CD167a can be phosphorylated on Y513. Animal studies suggest that CD167a is involved in arterial wound healing. The 51D6 antibody has been shown to be useful for flow cytometric detection of human CD167a as well as immunoprecipitation.
Purification The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Clone 51D6
Isotype IgG3 kappa

Target Details MCK10

Product Details anti-MCK10 Antibody Application Details Handling References for anti-MCK10 Antibody (ABIN2663088) Images back to top
Antigen
Alternative Name CD167a (DDR1 Antibody Abstract)
Pathways RTK Signaling

Application Details

Product Details anti-MCK10 Antibody Target Details MCK10 Handling References for anti-MCK10 Antibody (ABIN2663088) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-MCK10 Antibody Target Details MCK10 Application Details References for anti-MCK10 Antibody (ABIN2663088) Images back to top
Buffer Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Protect from prolonged exposure to light. Do not freeze.
Storage 4 °C
Storage Comment The antibody solution should be stored undiluted between 2°C and 8°C.

References for anti-MCK10 Antibody (ABIN2663088)

Product Details anti-MCK10 Antibody Target Details MCK10 Application Details Handling Images back to top
Background publications

Rudra-Ganguly, Lowe, Mattie, Chang, Satpayev, Verlinsky, An, Hu, Yang, Challita-Eid, Stover, Pereira: "Discoidin domain receptor 1 contributes to tumorigenesis through modulation of TGFBI expression." in: PLoS ONE, Vol. 9, Issue 11, pp. e111515, 2014

Hou, Vogel, Bendeck: "The discoidin domain receptor tyrosine kinase DDR1 in arterial wound repair." in: The Journal of clinical investigation, Vol. 107, Issue 6, pp. 727-35, 2001

Sakuma, Saya, Tada, Nakao, Fujiwara, Roth, Sawamura, Shinohe, Abe: "Receptor protein tyrosine kinase DDR is up-regulated by p53 protein." in: FEBS letters, Vol. 398, Issue 2-3, pp. 165-9, 1997

Di Marco, Cutuli, Guerra, Cancedda, De Luca: "Molecular cloning of trkE, a novel trk-related putative tyrosine kinase receptor isolated from normal human keratinocytes and widely expressed by normal human tissues." in: The Journal of biological chemistry, Vol. 268, Issue 32, pp. 24290-5, 1993

Johnson, Edman, Rutter: "A receptor tyrosine kinase found in breast carcinoma cells has an extracellular discoidin I-like domain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 90, Issue 12, pp. 5677-81, 1993

Images

Product Details anti-MCK10 Antibody Target Details MCK10 Application Details Handling References for anti-MCK10 Antibody (ABIN2663088) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-MCK10 antibody (Discoidin Domain Receptor Family, Member 1)  (PE) (ABIN2663088) anti-Discoidin Domain Receptor Family, Member 1 (DDR1) antibody (PE)