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anti-Human MCK10 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended MCK10 Antibody (supplied by: Log in to see )

Antigen
Discoidin Domain Receptor Family, Member 1 (DDR1) Antibodies
  • DDR1
  • DDR
  • 6030432F18
  • AI323681
  • CD167a
  • Cak
  • Nep
  • PTK3A
  • CAK
  • CD167
  • EDDR1
  • HGK2
  • MCK10
  • NEP
  • NTRK4
  • PTK3
  • RTK6
  • TRKE
  • Drd1
  • PTK3D
  • discoidin domain receptor tyrosine kinase 1
  • discoidin domain receptor family, member 1
  • DDR1
  • ddr1
  • Ddr1
Reactivity
Human
16
6
6
Host
Rabbit
11
5
Clonality
Polyclonal
Conjugate
This MCK10 antibody is un-conjugated
2
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
9
4
4
3
2
1
1
1
Supplier
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Catalog No. ABIN359899
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN359897 EIA FACS IHC (p) WB Rabbit Ig N-Term Log in to see Polyclonal 5
1 ABIN614409 EIA IHC (p) WB Mouse IgG1 AA 602-681 Log in to see 2G4E12
1 ABIN302427 IHC (p) Rabbit N-Term Log in to see Polyclonal
1 ABIN302391 IHC (p) Rabbit C-Term Log in to see Polyclonal

Top referenced anti-MCK10 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-MCK10 Antibodies

Application / Reactivity Human
ELISA 2 Antibodies
Enzyme Immunoassay (EIA) 4 Antibodies
Flow Cytometry (FACS) 4 Antibodies
Immunofluorescence (IF) 1 Antibodies
Immunohistochemistry (IHC) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 5 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Western Blotting (WB) 10 Antibodies

General

Antigen Discoidin Domain Receptor Family, Member 1 (DDR1) Antibodies
Reactivity Human
(16), (6), (6)
Host Rabbit
(11), (5)
Clonality
Polyclonal
Conjugate This MCK10 antibody is un-conjugated
(2), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(9), (4), (4), (3), (2), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-MCK10 Antibody

Target Details MCK10 Application Details Handling References for anti-MCK10 Antibody (ABIN359899) Images
Specificity This antibody reacts to MCK10.
Purification Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with recombinant human MCK10 protein.
Isotype Ig

Target Details MCK10

Product Details anti-MCK10 Antibody Application Details Handling References for anti-MCK10 Antibody (ABIN359899) Images back to top
Antigen
Alternative Name CD167a / DDR1 (DDR1 Antibody Abstract)
Background Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. MCK10 is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI). In situ studies and Northern-blot analysis showed that expression of this encoded protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, this protein is significantly over-expressed in several human tumors from breast, ovarian, esophageal, and pediatric brain.Synonyms: CAK, CD167 antigen-like family member A, EDDR1, Epithelial discoidin domain receptor 1, Epithelial discoidin domain-containing receptor 1, MCK10, NEP, NTRK4, PTK3A, RTK6, TRKE, Tyrosine kinase DDR-1
Gene ID 780, 9606
UniProt Q08345
Pathways RTK Signaling

Application Details

Product Details anti-MCK10 Antibody Target Details MCK10 Handling References for anti-MCK10 Antibody (ABIN359899) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-MCK10 Antibody Target Details MCK10 Application Details References for anti-MCK10 Antibody (ABIN359899) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-MCK10 Antibody (ABIN359899)

Product Details anti-MCK10 Antibody Target Details MCK10 Application Details Handling Images back to top
Background publications

Vogel, Gish, Alves, Pawson: "The discoidin domain receptor tyrosine kinases are activated by collagen." in: Molecular cell, Vol. 1, Issue 1, pp. 13-23, 1998

Ghauri, Chapman, Meldrum: "Convulsant and anticonvulsant actions of agonists and antagonists of group III mGluRs." in: Neuroreport, Vol. 7, Issue 9, pp. 1469-74, 1997

Playford, Butler, Wang, Katso, Cooke, Ganesan: "The genomic structure of discoidin receptor tyrosine kinase." in: Genome research, Vol. 6, Issue 7, pp. 620-7, 1996

Valent, Meddeb, Danglot, Duverger, Nguyen, Bernheim: "Assignment of the NTRK4 (trkE) gene to chromosome 6p21." in: Human genetics, Vol. 98, Issue 1, pp. 12-5, 1996

Edelhoff, Sweetser, Disteche: "Mapping of the NEP receptor tyrosine kinase gene to human chromosome 6p21.3 and mouse chromosome 17C." in: Genomics, Vol. 25, Issue 1, pp. 309-11, 1995

Images

Product Details anti-MCK10 Antibody Target Details MCK10 Application Details Handling References for anti-MCK10 Antibody (ABIN359899) back to top
Supplier Images
 image for anti-MCK10 antibody (Discoidin Domain Receptor Family, Member 1) (ABIN359899) anti-Discoidin Domain Receptor Family, Member 1 (DDR1) antibody
 image for anti-MCK10 antibody (Discoidin Domain Receptor Family, Member 1) (ABIN359899) anti-Discoidin Domain Receptor Family, Member 1 (DDR1) antibody (Image 2)