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Browse our anti-MERTK (MERTK) Antibodies

Full name:
anti-C-Mer Proto-Oncogene Tyrosine Kinase Antibodies (MERTK)
On are 158 C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) Antibodies from 25 different suppliers available. Additionally we are shipping MERTK Proteins (21) and MERTK Kits (20) and many more products for this protein. A total of 215 MERTK products are currently listed.
C-EYK, c-mer, DKFZp469D2215, Eyk, Mer, MERTK, nmf12, Nyk, rdy, RP38, si:ch1073-268l12.2
list all antibodies Gene Name GeneID UniProt
MERTK 10461 Q12866
MERTK 17289 Q60805
MERTK 65037 P57097

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anti-Human MERTK Antibodies:

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anti-Rat (Rattus) MERTK Antibodies:

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Top referenced anti-MERTK Antibodies

  1. Human Polyclonal MERTK Primary Antibody for EIA, WB - ABIN359900 : Graham, Dawson, Mullaney, Snodgrass, Earp: Cloning and mRNA expression analysis of a novel human protooncogene, c-mer. in Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994 (PubMed)
    Show all 3 references for ABIN359900

  2. Human Monoclonal MERTK Primary Antibody for ELISA, WB - ABIN969283 : McGough, Cummings: Coeliac disease: a diverse clinical syndrome caused by intolerance of wheat, barley and rye. in The Proceedings of the Nutrition Society 2005 (PubMed)
    Show all 3 references for ABIN969283

  3. Human Monoclonal MERTK Primary Antibody for WB - ABIN1042623 : Graham, Salzberg, Kurtzberg, Sather, Matsushima, Keating, Liang, Lovell, Williams, Dawson, Schell, Anwar, Snodgrass, Earp: Ectopic expression of the proto-oncogene Mer in pediatric T-cell acute lymphoblastic leukemia. in Clinical cancer research : an official journal of the American Association for Cancer Research 2006 (PubMed)
    Show all 2 references for ABIN1042623

  4. Human Polyclonal MERTK Primary Antibody for WB - ABIN493125 : DCruz, Yasumura, Weir, Matthes, Abderrahim, LaVail, Vollrath: Mutation of the receptor tyrosine kinase gene Mertk in the retinal dystrophic RCS rat. in Human molecular genetics 2000 (PubMed)
    Show all 2 references for ABIN493125

  5. Human Polyclonal MERTK Primary Antibody for IHC (fro), IP - ABIN2712097 : Gal, Li, Thompson, Weir, Orth, Jacobson, Apfelstedt-Sylla, Vollrath: Mutations in MERTK, the human orthologue of the RCS rat retinal dystrophy gene, cause retinitis pigmentosa. in Nature genetics 2000 (PubMed)
    Show all 2 references for ABIN2712097

  6. Human Polyclonal MERTK Primary Antibody for IHC (p), WB - ABIN392017 : Thompson, McHenry, Li, Richards, Othman, Schwinger, Vollrath, Jacobson, Gal: Retinal dystrophy due to paternal isodisomy for chromosome 1 or chromosome 2, with homoallelism for mutations in RPE65 or MERTK, respectively. in American journal of human genetics 2001 (PubMed)
    Show all 2 references for ABIN392017

  7. Human Polyclonal MERTK Primary Antibody for EIA, WB - ABIN360227 : Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... in Nature 2005 (PubMed)
    Show all 2 references for ABIN360227

More Antibodies against MERTK Interaction Partners

Human C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) interaction partners

  1. Utilizing an ex vivo co-cultivation approach to model key cellular and molecular events found in vivo during infarction, cardiomyocyte phagocytosis was found to be inefficient, in part due to myocyte-induced shedding of macrophage MERTK

  2. Upon differentiation of these iPSC towards RPE (show RPE Antibodies), patient-specific RPE (show RPE Antibodies) cells exhibited defective phagocytosis, a characteristic phenotype of MERTK deficiency observed in human patients and animal models

  3. The current study demonstrates the contribution of the TAM (show CCNA1 Antibodies) receptor MerTK to the phagocytosis of myelin by human adult microglia and monocyte-derived macrophages.

  4. One of the associated variants was also found to be linked with increased expression of MERTK in monocytes and higher expression of MERTK was associated with either increased or decreased risk of developing MS, dependent upon HLA-DRB1 (show HLA-DRB1 Antibodies)*15:01 status.

  5. Combined Mertk (and Mfge8 (show MFGE8 Antibodies)) deficiency in macrophages blunted VEGFA (show VEGFA Antibodies) release from infarcted hearts.

  6. Studies indicate that c-Mer receptor tyrosine kinase MERTK mutations cause retinal degenerations.

  7. Data indicate that AAV2-VMD2 (show BEST1 Antibodies)-c-mer proto-oncogene (show RAB1A Antibodies) protein (hMERTK) provided up to 6.5 months photoreceptor rescue in the RCS (show ARPP21 Antibodies) rat, and also had a major protective effect in Mertk-null mice.

  8. Data show that activated AMP-activated protein kinase (AMPK (show PRKAA2 Antibodies)) limits retinal pigment epithelial cells (RPE (show RPE Antibodies)) phagocytic activity by abolishing retinal photoreceptor cell outer segment (POS)-induced activation of c-mer proto-oncogene tyrosine kinase (MerTK).

  9. The mRNA expression levels of Tyro-3 (show TYRO3 Antibodies), Axl (show AXL Antibodies) were decreased in pSS (show CDSN Antibodies) patients. When considering the plasma level, increased levels of soluble Mer was observed with statistically significant difference.

  10. Mer enhances malignant phenotype and pharmacological inhibition of Mer overcomes resistance of non-small cell lung cancer to EGFR (show EGFR Antibodies)-targeted agents.

Mouse (Murine) C-Mer Proto-Oncogene Tyrosine Kinase (MERTK) interaction partners

  1. These studies define the clearance of infected, apoptotic neutrophils by dendritic cells and Mer (show ERH Antibodies) receptor signaling as central to the early immune evasion strategies of L. major.

  2. Tyro3 gene dosage modulates Mertk-associated retinal degeneration, provide strong evidence for a direct role for TYRO3 in RPE phagocytosis, and suggest that an eQTL can modify a recessive Inherited photoreceptor degenerations.

  3. Activation of Mertk synergized with interferon-beta (show IFNB1 Antibodies) to tighten cell junctions and prevent virus transit across brain microvascular endothelial cells.

  4. results establish TAM (show CCNA1 Antibodies) receptors as both controllers of microglial physiology and potential targets for therapeutic intervention in central nervous system disease

  5. Loss of Mertk alters expression of micrornas in retinal pigment epithelial cells.

  6. These results suggest that TAM (show CCNA1 Antibodies) receptors support NSCs survival, proliferation and differentiation by regulating expression of neurotrophins, especially the nerve growth factor.

  7. Mertk deficiency affects not only phagocytosis but also cell shape and migration

  8. The results indicate that Axl (show AXL Antibodies) and Mer (show ERH Antibodies) receptors cooperatively regulate the systemic immune tolerance to male germ cell antigens.

  9. Enhanced Mer signaling during the recovery phase increases the abundance and activity of LXR to inactivate the inflammatory response in macrophages

  10. nuclear receptor agonists increase MerTK and Axl (show AXL Antibodies) expression on plaque-associated immune cells, consequently licensing their phagocytic activity and promoting plaque clearance.

MERTK Antigen Profile

Antigen Summary

This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP).

Alternative names and synonyms associated with MERTK

  • c-mer proto-oncogene tyrosine kinase (MERTK) antibody
  • c-mer proto-oncogene tyrosine kinase (LOC100219161) antibody
  • c-mer proto-oncogene tyrosine kinase (mertk) antibody
  • c-mer proto-oncogene tyrosine kinase (Mertk) antibody
  • C-EYK antibody
  • c-mer antibody
  • DKFZp469D2215 antibody
  • Eyk antibody
  • Mer antibody
  • MERTK antibody
  • nmf12 antibody
  • Nyk antibody
  • rdy antibody
  • RP38 antibody
  • si:ch1073-268l12.2 antibody

Protein level used designations for MERTK

c-eyk proto-oncogene , tyrosine-protein kinase Mer , c-mer proto-oncogene tyrosine kinase , MER receptor tyrosine kinase , tyrosine-protein kinase Mer-like , STK kinase , proto-oncogene c-Mer , receptor tyrosine kinase MerTK , Tyro 12 , proto-oncogene tyrosine-protein kinase Mer , Receptor tyrosine tinase gene probably the gene for Rdy , proto-oncogene tyrosine-protein kinase MER , retinal dystrophy

395836 Gallus gallus
459492 Pan troglodytes
483060 Canis lupus familiaris
504429 Bos taurus
698330 Macaca mulatta
100171862 Pongo abelii
100219161 Taeniopygia guttata
100322133 Danio rerio
100476239 Ailuropoda melanoleuca
10461 Homo sapiens
17289 Mus musculus
65037 Rattus norvegicus
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