anti-Human MME antibody for Enzyme Immunoassay

Recommended MME Antibody (supplied by: Log in to see )

Antigen
Membrane Metallo-Endopeptidase (MME) Antibodies
  • MME
  • NEP
  • CD10
  • CALLA
  • CAK
  • CD167
  • DDR
  • EDDR1
  • HGK2
  • MCK10
  • NTRK4
  • PTK3
  • PTK3A
  • RTK6
  • TRKE
  • AV378681
  • Mmel
  • 6030454K05Rik
  • C85356
  • SFE
  • Nep
  • membrane metallo-endopeptidase
  • discoidin domain receptor tyrosine kinase 1
  • matrix metallopeptidase 12
  • membrane metallo endopeptidase
  • MME
  • DDR1
  • Mmp12
  • Mme
Reactivity
Human
634
99
83
16
14
4
3
3
2
2
2
2
1
1
1
1
Host
Mouse
447
197
7
3
Clonality
Monoclonal
Conjugate
This MME antibody is un-conjugated
61
49
44
23
11
11
11
10
10
9
6
6
6
6
6
5
5
5
5
4
4
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
327
312
216
181
128
85
84
49
49
21
13
10
7
4
3
2
2
2
2
2
1
1
1
1
Supplier
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Catalog No. ABIN5611377
$ 542.85
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5553800 EIA IHC (p) WB Rabbit C-Term Log in to see Polyclonal
1 ABIN5556281 EIA IHC (p) WB Rabbit Ig Fraction AA 728-755, Middle Region Log in to see Polyclonal
1 ABIN2717217 EIA IHC (p) WB Rabbit IgG Log in to see Polyclonal

General

Antigen Membrane Metallo-Endopeptidase (MME) Antibodies
Reactivity Human
(634), (99), (83), (16), (14), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Host Mouse
(447), (197), (7), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This MME antibody is un-conjugated
(61), (49), (44), (23), (11), (11), (11), (10), (10), (9), (6), (6), (6), (6), (6), (5), (5), (5), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(327), (312), (216), (181), (128), (85), (84), (49), (49), (21), (13), (10), (7), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
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Product Details anti-MME Antibody

Target Details MME Application Details Handling Images
Specificity This antibody detects Membrane Metallo-Endopeptidase (MME/Neprilysin)/ (CD10) (Family: Protease, Subfamily: Metallopeptidase M13).
Cross-Reactivity (Details) Species reactivity (tested):Human.
Characteristics Synonyms: MME, EPN, Neutral endopeptidase 24.11, Neutral endopeptidase, NEP, Enkephalinase,Atriopeptidase, CALLA, Common acute lymphocytic leukemia antigen
Purification Protein G Chromatography
Immunogen Ni-NTA purified recombinant Human CD-10 expressed in E. Coli strain BL21 (DE3)
Clone N-a
Isotype IgG2b

Target Details MME

Product Details anti-MME Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD10 / Neprilysin (MME Antibody Abstract)
Background MME, also known as Neprilysin or CALLA for common acute lymphocytic leukemia antigen, is a Metallopeptidase M13 type protease. MME functions as a peptidase and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. The protein is found on leukemic cells of pre-B phenotype and serves as a cell-surface marker in the diagnosis of human acute lymphocytic leukemia (ALL).Synonyms: Atriopeptidase, CALLA, Common acute lymphocytic leukemia antigen, EPN, Enkephalinase, MME, NEP, Neutral endopeptidase, Neutral endopeptidase 24.11
Gene ID 4311
UniProt P08473
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration

Application Details

Product Details anti-MME Antibody Target Details MME Handling Images back to top
Application Notes ELISA (1/10000). Immunohistochemistry on Frozen Sections (1/200-1/400). Immunohistochemistry onParaffin Sections (1/100-1/200). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-MME Antibody Target Details MME Application Details Images back to top
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4, 0.03 % Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.
Expiry Date 12 months

Images

Product Details anti-MME Antibody Target Details MME Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Membrane Metallo-Endopeptidase (MME) antibody (ABIN5611377) anti-Membrane Metallo-Endopeptidase (MME) antibody