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anti-Human MME antibody for Immunofluorescence

Recommended MME Antibody (supplied by: Log in to see )

Antigen
Membrane Metallo-Endopeptidase (MME) Antibodies
  • 6030454K05Rik
  • AV378681
  • C85356
  • CAK
  • CALLA
  • CD10
  • CD167
  • DDR
  • EDDR1
  • HGK2
  • MCK10
  • MME
  • Mmel
  • Nep
  • NEP
  • NTRK4
  • PTK3
  • PTK3A
  • RTK6
  • SFE
  • TRKE
Epitope
AA 274-302, Center
34
21
19
16
14
11
7
6
6
6
6
6
5
5
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
564
64
63
13
13
1
Host
Rabbit
403
176
3
Clonality
Polyclonal
Conjugate
This MME antibody is un-conjugated
60
49
35
24
9
7
7
7
7
5
5
4
4
4
4
4
4
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
292
254
134
131
99
74
67
52
46
14
11
8
5
4
3
2
2
2
1
1
Supplier
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Catalog No. ABIN391500
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0010843398 ABIN2145054 FACS IF Mouse IgG1 Log in to see 4ACB-CALLA 2
0.0010843398 ABIN2145055 FACS IF Mouse IgG1 Log in to see 4ACB-CALLA 2
0.0010843398 ABIN2144484 FACS IF FITC Mouse IgG1 Log in to see 4ACB-CALLA 2
0.0010843398 ABIN2144486 FACS IF FITC Mouse IgG1 Log in to see 4ACB-CALLA 2
0.0010843398 ABIN2144775 FACS IF PE Mouse IgG1 Log in to see 4ACB-CALLA 2
0.0010843398 ABIN2144777 FACS IF PE Mouse IgG1 Log in to see 4ACB-CALLA 2
0.0010843398 ABIN2661448 Func ICC FACS IF ICFC FITC Mouse IgG1 kappa Log in to see HI10a 5
0.0010843398 ABIN2660629 FACS IF APC-Cy7 Mouse IgG1 kappa Log in to see HI10a 5
0.0010843398 ABIN2659926 FACS IF IHC PerCP-Cy5.5 Mouse IgG1 kappa Log in to see HI10a 6
0.0010843398 ABIN2661449 Func ICC FACS IF ICFC FITC Mouse IgG1 kappa Log in to see HI10a 5
0.0010843398 ABIN2659927 FACS IF IHC PerCP-Cy5.5 Mouse IgG1 kappa Log in to see HI10a 6
0.0010843398 ABIN2851660 FACS IF PE Mouse IgG1 Log in to see
0.0010843398 ABIN2851768 FACS IF FITC Mouse IgG1 Log in to see
0.0010843398 ABIN2707981 FACS IF Mouse IgG1 Log in to see
0.0010843398 ABIN219362 FACS IF PE Mouse IgG1, kappa Log in to see
0.0010843398 ABIN1502401 FACS IF IHC Mouse IgG1 Log in to see B396
0.0010843398 ABIN1112037 FACS IF APC Mouse IgG1 Log in to see HI10a
0.0010843398 ABIN2221831 FACS IF PE Mouse IgG1 kappa Log in to see 5F12
0.0010843398 ABIN4338611 FACS IF Mouse IgG2b kappa Log in to see CB-CALLA
0.0010843398 ABIN4338612 FACS IF Mouse IgG2b kappa Log in to see CB-CALLA

Top referenced anti-MME antibody for Immunofluorescence

Similar anti-MME Antibodies

Application / Reactivity Mouse (Murine) Human
Confocal Microscopy (CM) 14 Antibodies 14 Antibodies
ELISA 26 Antibodies 124 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 5 Antibodies
Flow Cytometry (FACS) 2 Antibodies 302 Antibodies
Immunocytochemistry (ICC) 15 Antibodies
Immunofluorescence (IF) 16 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 26 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 11 Antibodies
Immunoprecipitation (IP) 16 Antibodies
Western Blotting (WB) 47 Antibodies
Complement Mediated Cell Depletion (CMCD) 2 Antibodies
Functional Studies (Func) 4 Antibodies
Immunoassay (IA) 1 Antibodies

General

Antigen Membrane Metallo-Endopeptidase (MME) Antibodies
Epitope AA 274-302, Center
(34), (21), (19), (16), (14), (11), (7), (6), (6), (6), (6), (6), (5), (5), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(564), (64), (63), (13), (13), (1)
Host Rabbit
(403), (176), (3)
Clonality (Clone)
Polyclonal   ( )
Conjugate This MME antibody is un-conjugated
(60), (49), (35), (24), (9), (7), (7), (7), (7), (5), (5), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (IF), Western Blotting (WB)
(292), (254), (134), (131), (99), (74), (67), (52), (46), (14), (11), (8), (5), (4), (3), (2), (2), (2), (1), (1)
Pubmed 4 references available
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Product Details anti-MME Antibody

Target Details MME Application Details Handling References for anti-MME Antibody (ABIN391500) Images
Specificity This MME antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281~310 amino acids from the Center region of human MME.
Predicted Reactivity Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen This MME antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 274-302 AA from the Central region of human MME.
Clone RB18820
Isotype Ig

Target Details MME

Product Details anti-MME Antibody Application Details Handling References for anti-MME Antibody (ABIN391500) Images back to top
Antigen
Alternative Name MME (MME Antibody Abstract)
Background MME is a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a oprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.
Synonyms: Neprilysin, Neutral endopeptidase 24.11, Neutral endopeptidase, NEP, Enkephalinase, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, CD_antigen=CD10, EPN, MME
Molecular Weight 85514 DA
Gene ID 4311
UniProt P08473
Research Area Cell Structure
Pathways RTK Signaling

Application Details

Product Details anti-MME Antibody Target Details MME Handling References for anti-MME Antibody (ABIN391500) Images back to top
Application Notes WB = 1:1000, IF = 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-MME Antibody Target Details MME Application Details References for anti-MME Antibody (ABIN391500) Images back to top
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

References for anti-MME Antibody (ABIN391500)

Product Details anti-MME Antibody Target Details MME Application Details Handling Images back to top
Background publications

Dakka, Bellaoui, Bouzid, Khattab, Bakri, Benjouad: "CD10 AND CD34 expression in childhood acute lymphoblastic leukemia in Morocco: clinical relevance and outcome." in: Pediatric hematology and oncology, Vol. 26, Issue 4, pp. 216-31, 2009

Wang, Wang, Malter, Wang: "Effects of HNE-modification induced by Abeta on neprilysin expression and activity in SH-SY5Y cells." in: Journal of neurochemistry, Vol. 108, Issue 4, pp. 1072-82, 2009

Shipp, Tarr, Chen, Switzer, Hersh, Stein, Sunday, Reinherz: "CD10/neutral endopeptidase 24.11 hydrolyzes bombesin-like peptides and regulates the growth of small cell carcinomas of the lung." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 23, pp. 10662-6, 1992

Shipp, Vijayaraghavan, Schmidt, Masteller, DAdamio, Hersh, Reinherz: "Common acute lymphoblastic leukemia antigen (CALLA) is active neutral endopeptidase 24.11 ("enkephalinase"): direct evidence by cDNA transfection analysis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 1, pp. 297-301, 1989

Images

Product Details anti-MME Antibody Target Details MME Application Details Handling References for anti-MME Antibody (ABIN391500) back to top
Supplier Images
Western Blotting (WB) image for anti-MME antibody (Membrane Metallo-Endopeptidase) (AA 274-302) (ABIN391500) Western blot analysis of Neprilysin antibody (Center) (ABIN391500) in mouse kidney ti...