anti-Human MME antibody for Western Blotting

Recommended MME Antibody (supplied by: Log in to see )

Antigen
Membrane Metallo-Endopeptidase (MME) Antibodies
  • MME
  • NEP
  • CD10
  • CALLA
  • CAK
  • CD167
  • DDR
  • EDDR1
  • HGK2
  • MCK10
  • NTRK4
  • PTK3
  • PTK3A
  • RTK6
  • TRKE
  • AV378681
  • Mmel
  • 6030454K05Rik
  • C85356
  • SFE
  • Nep
  • membrane metallo-endopeptidase
  • discoidin domain receptor tyrosine kinase 1
  • matrix metallopeptidase 12
  • membrane metallo endopeptidase
  • MME
  • DDR1
  • Mmp12
  • Mme
Epitope
AA 506-534, C-Term
36
36
23
16
15
14
13
12
10
8
8
6
5
5
5
5
4
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1
Reactivity
Human
620
97
83
16
14
4
3
3
2
2
2
2
1
1
1
1
Host
Rabbit
438
195
4
3
Clonality
Polyclonal
Conjugate
This MME antibody is un-conjugated
61
48
43
23
11
10
10
10
9
8
6
6
6
6
6
5
5
5
5
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
313
304
212
178
129
83
83
50
49
21
13
10
5
4
3
2
2
2
1
1
1
1
1
1
Options
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Catalog No. ABIN391499
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
3.3459496 ABIN391500 IF WB Rabbit Ig AA 274-302, Center Log in to see Polyclonal 4
3.3459496 ABIN659195 WB Mouse IgM AA 272-300 Log in to see 307CT12-12-5 2
3.3459496 ABIN1687388 IHC (p) WB Rabbit IgG Log in to see SP67 5
3.3459496 ABIN1724916 IHC ELISA WB Mouse IgG1 AA 52-246 Log in to see 5E9A5 1
3.3459496 ABIN1724914 IHC ELISA WB Mouse IgG1 AA 52-246 Log in to see 7D4B1 1
3.3459496 ABIN3043879 IHC (p) WB Rabbit IgG AA 52-750 Log in to see Polyclonal
3.3459496 ABIN969011 IHC ELISA WB Mouse IgG1 Log in to see 3G9D10 2
3.3459496 ABIN4900407 ELISA (Capture) FACS IHC IP WB Goat IgG AA 52-750 Log in to see Polyclonal 2
3.3459496 ABIN2789467 WB Rabbit C-Term Log in to see Polyclonal
3.3459496 ABIN1688911 FACS IHC (p) WB Rabbit IgG N-Term Log in to see SP179
3.3459496 ABIN3187862 ELISA IHC (p) WB Rabbit IgG Internal Region Log in to see Polyclonal
3.3459496 ABIN3197939 FACS IP WB Rabbit Log in to see Polyclonal
3.3459496 ABIN1539806 WB Mouse IgM, kappa AA 272-300 Log in to see 307CT12-12-5
3.3459496 ABIN4338600 IHC IHC (p) WB Rabbit IgG Center Log in to see Polyclonal
3.3459496 ABIN4903167 IHC WB Rabbit IgG Log in to see Polyclonal
3.3459496 ABIN1876865 FACS IHC IP WB Rabbit IgG Log in to see Polyclonal
3.3459496 ABIN4338595 ELISA IHC WB Mouse IgG1 Log in to see 5E9A5
3.3459496 ABIN4338614 IHC WB Mouse IgG2a Log in to see 3D11
3.3459496 ABIN4338596 ELISA IHC IHC (p) WB Mouse IgG1 Log in to see 7D4B1
3.3459496 ABIN1175016 ICC IHC IP WB Rabbit IgG AA 382-538 Log in to see Polyclonal

Top referenced anti-MME antibody for Western Blotting

Similar anti-MME Antibodies

Application / Reactivity Human
Complement Mediated Cell Depletion (CMCD) 2 Antibodies
Confocal Microscopy (CM) 21 Antibodies
Cytometry by Time of Flight (CyTOF) 3 Antibodies
ELISA 165 Antibodies
ELISA (Capture) 1 Antibodies
ELISA (Detection) 1 Antibodies
Enzyme Immunoassay (EIA) 5 Antibodies
Flow Cytometry (FACS) 314 Antibodies
Functional Studies (Func) 4 Antibodies
Immunoassay (IA) 1 Antibodies
Immunocytochemistry (ICC) 46 Antibodies
Immunofluorescence (IF) 83 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 7 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 202 Antibodies
Immunohistochemistry (Acetone-fixed) (IHC (af)) 1 Antibodies

General

Antigen Membrane Metallo-Endopeptidase (MME) Antibodies
Epitope AA 506-534, C-Term
(36), (36), (23), (16), (15), (14), (13), (12), (10), (8), (8), (6), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Reactivity Human
(620), (97), (83), (16), (14), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Host Rabbit
(438), (195), (4), (3)
Clonality (Clone)
Polyclonal   ( )
Conjugate This MME antibody is un-conjugated
(61), (48), (43), (23), (11), (10), (10), (10), (9), (8), (6), (6), (6), (6), (6), (5), (5), (5), (5), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(313), (304), (212), (178), (129), (83), (83), (50), (49), (21), (13), (10), (5), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-MME Antibody

Target Details MME Application Details Handling ProductDetails: References for anti-MME antibody (ABIN391499) Images
Specificity This Neprilysin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 513~542 amino acids from the C-terminal region of human Neprilysin.
Predicted Reactivity Mouse (Murine),Rat (Rattus),Rabbit
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen This Neprilysin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 506-534 AA from the C-terminal region of human Neprilysin.
Clone RB18821
Isotype Ig

Target Details MME

Product Details anti-MME Antibody Application Details Handling ProductDetails: References for anti-MME antibody (ABIN391499) Images back to top
Antigen
Alternative Name Neprilysin (MME Antibody Abstract)
Background MME is a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a oprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin.
Synonyms: Neprilysin, Neutral endopeptidase 24.11, Neutral endopeptidase, NEP, Enkephalinase, Atriopeptidase, Common acute lymphocytic leukemia antigen, CALLA, CD_antigen=CD10, EPN, MME
Molecular Weight 85514 DA
Gene ID 4311
UniProt P08473
Research Area Cell Structure
Pathways RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration

Application Details

Product Details anti-MME Antibody Target Details MME Handling ProductDetails: References for anti-MME antibody (ABIN391499) Images back to top
Application Notes WB = 1:1000, IHC (p) = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-MME Antibody Target Details MME Application Details ProductDetails: References for anti-MME antibody (ABIN391499) Images back to top
Format Liquid
Concentration 0.4 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

ProductDetails: References for anti-MME antibody (ABIN391499)

Product Details anti-MME Antibody Target Details MME Application Details Handling Images back to top
Background publications

Dakka, Bellaoui, Bouzid, Khattab, Bakri, Benjouad: "CD10 AND CD34 expression in childhood acute lymphoblastic leukemia in Morocco: clinical relevance and outcome." in: Pediatric hematology and oncology, Vol. 26, Issue 4, pp. 216-31, 2009

Wang, Wang, Malter, Wang: "Effects of HNE-modification induced by Abeta on neprilysin expression and activity in SH-SY5Y cells." in: Journal of neurochemistry, Vol. 108, Issue 4, pp. 1072-82, 2009

Shipp, Tarr, Chen, Switzer, Hersh, Stein, Sunday, Reinherz: "CD10/neutral endopeptidase 24.11 hydrolyzes bombesin-like peptides and regulates the growth of small cell carcinomas of the lung." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 23, pp. 10662-6, 1992

Shipp, Vijayaraghavan, Schmidt, Masteller, DAdamio, Hersh, Reinherz: "Common acute lymphoblastic leukemia antigen (CALLA) is active neutral endopeptidase 24.11 ("enkephalinase"): direct evidence by cDNA transfection analysis." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 86, Issue 1, pp. 297-301, 1989

Images

Product Details anti-MME Antibody Target Details MME Application Details Handling ProductDetails: References for anti-MME antibody (ABIN391499) back to top
Supplier Images
Western Blotting (WB) image for anti-MME antibody (Membrane Metallo-Endopeptidase) (AA 506-534) (ABIN391499) Western blot analysis of Neprilysin Antibody (C-term) (ABIN391499) in A2058,A375,Ramo...
Immunohistochemistry (IHC) image for anti-MME antibody (Membrane Metallo-Endopeptidase) (AA 506-534) (ABIN391499) Formalin-fixed and paraffin-embedded human kidney carcinoma with Neprilysin Antibody ...
Flow Cytometry (FACS) image for anti-MME antibody (Membrane Metallo-Endopeptidase) (AA 506-534) (ABIN391499) Neprilysin Antibody (C-term) (ABIN391499) flow cytometry analysis of Ramos cells (bot...