anti-Mouse (Murine) MME antibody for Enzyme Immunoassay

Recommended MME Antibody (supplied by: Log in to see )

Antigen
Membrane Metallo-Endopeptidase (MME) Antibodies
  • MME
  • NEP
  • CD10
  • CALLA
  • CAK
  • CD167
  • DDR
  • EDDR1
  • HGK2
  • MCK10
  • NTRK4
  • PTK3
  • PTK3A
  • RTK6
  • TRKE
  • AV378681
  • Mmel
  • 6030454K05Rik
  • C85356
  • SFE
  • Nep
  • membrane metallo-endopeptidase
  • discoidin domain receptor tyrosine kinase 1
  • matrix metallopeptidase 12
  • membrane metallo endopeptidase
  • MME
  • DDR1
  • Mmp12
  • Mme
Epitope
AA 728-755, Middle Region
37
36
23
16
16
15
14
14
13
10
8
6
6
5
5
5
4
4
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
Reactivity
Human, Mouse (Murine)
634
98
83
16
14
4
3
3
2
2
2
2
1
1
1
1
Host
Rabbit
448
196
7
3
Clonality
Polyclonal
Conjugate
This MME antibody is un-conjugated
61
49
44
23
11
11
11
10
10
9
6
6
6
6
6
5
5
5
5
4
4
4
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
327
311
216
181
128
85
84
50
49
21
13
10
7
4
3
2
2
2
2
2
1
1
1
1
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Catalog No. ABIN5556281
$ 375.38
Plus shipping costs $45.00

General

Antigen Membrane Metallo-Endopeptidase (MME) Antibodies
Epitope AA 728-755, Middle Region
(37), (36), (23), (16), (16), (15), (14), (14), (13), (10), (8), (6), (6), (5), (5), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Reactivity Human, Mouse (Murine)
(634), (98), (83), (16), (14), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Host Rabbit
(448), (196), (7), (3)
Clonality
Polyclonal
Conjugate This MME antibody is un-conjugated
(61), (49), (44), (23), (11), (11), (11), (10), (10), (9), (6), (6), (6), (6), (6), (5), (5), (5), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(327), (311), (216), (181), (128), (85), (84), (50), (49), (21), (13), (10), (7), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
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Product Details anti-MME Antibody

Target Details MME Application Details Handling Images
Specificity This antibody recognizes Human and Mouse CD10 / Neprilysin (Center).
Purification Protein A column, followed by peptide affinity purification
Immunogen KLH conjugated synthetic peptide between 728-755 amino acids from the Central region of Human CD10 / Neprilysin. Genename: MME
Isotype Ig Fraction

Target Details MME

Product Details anti-MME Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD10 / Neprilysin (MME Antibody Abstract)
Background This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85 % of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq].Synonyms: Atriopeptidase, CALLA, Common acute lymphocytic leukemia antigen, EPN, Enkephalinase, MME, NEP, Neutral endopeptidase, Neutral endopeptidase 24.11
Molecular Weight 85514 Da
Gene ID 4311
NCBI Accession NP_000893
Research Area CD Antigens, Surface Receptors of Immune Cells
Pathways RTK Signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration

Application Details

Product Details anti-MME Antibody Target Details MME Handling Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-MME Antibody Target Details MME Application Details Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.