You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Mouse (Murine) MUSK antibody for Immunohistochemistry

Recommended MUSK Antibody (supplied by: Log in to see )

Antigen
Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK) Antibodies
  • unp
  • fj98e12
  • zgc:63467
  • wu:fj98e12
  • si:dz46m7.2
  • si:dz57f23.3
  • si:busm1-57f23.3
  • musk-A
  • MuSK
  • MUSK
  • Mdk4
  • Mlk
  • Nsk1
  • Nsk2
  • Nsk3
  • muscle
  • muscle, skeletal, receptor tyrosine kinase
  • MUSK
  • musk
  • musk-A
  • Musk
Reactivity
Mouse (Murine), Rat (Rattus)
115
48
38
2
1
1
Host
Mouse
96
26
3
Clonality
Monoclonal
Conjugate
This MUSK antibody is un-conjugated
6
6
5
4
4
4
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
93
71
60
27
19
13
11
5
4
3
3
1
1
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN3031880
$ 411.13
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
8.72946 ABIN2422809 IHC ELISA Rabbit IgG Log in to see Polyclonal
8.72946 ABIN2429415 IHC ELISA Rabbit IgG Log in to see Polyclonal
1 ABIN1873783 IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN267349 ICC IF IHC IHC (p) IP WB Rabbit IgG AA 210-304 Log in to see Polyclonal
1 ABIN1859913 ICC IHC IP WB Rabbit IgG AA 517-777 Log in to see Polyclonal
1 ABIN4336820 FACS IHC IHC (p) WB Rabbit N-Term Log in to see Polyclonal
1 ABIN2880353 IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN2887155 IHC WB Rabbit Log in to see Polyclonal
1 ABIN2974092 IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN2310006 IC IHC ELISA WB Rabbit IgG Log in to see Polyclonal
1 ABIN966610 IHC C-Term Log in to see Polyclonal 10
1 ABIN966612 IHC N-Term Log in to see Polyclonal 2
1 ABIN966611 IHC C-Term Log in to see Polyclonal 1
1 ABIN2915802 ELISA IF/ICC IHC WB Rabbit Log in to see Polyclonal

Top referenced anti-MUSK antibody for Immunohistochemistry

Similar anti-MUSK Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 11 Antibodies 17 Antibodies
Immunocytochemistry (ICC) 1 Antibodies 2 Antibodies
Immunofluorescence (IF) 1 Antibodies 3 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies 13 Antibodies
Immunohistochemistry (IHC) 11 Antibodies 15 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 6 Antibodies 7 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Western Blotting (WB) 21 Antibodies
Flow Cytometry (FACS) 3 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 2 Antibodies

General

Antigen Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK) Antibodies
Reactivity Mouse (Murine), Rat (Rattus)
(115), (48), (38), (2), (1), (1)
Host Mouse
(96), (26), (3)
Clonality (Clone)
Monoclonal   ( )
Conjugate This MUSK antibody is un-conjugated
(6), (6), (5), (4), (4), (4), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
(93), (71), (60), (27), (19), (13), (11), (5), (4), (3), (3), (1), (1), (1)
Supplier Log in to see

Product Details anti-MUSK Antibody

Target Details MUSK Application Details Handling Images
Purification Purified
Immunogen This mouse Musk antibody was produced from a mouse immunized with recombinant protein from a mouse Musk.
Clone 1429CT456-173-44
Isotype IgG1, kappa

Target Details MUSK

Product Details anti-MUSK Antibody Application Details Handling Images back to top
Antigen
Alternative Name Musk (MUSK Antibody Abstract)
Background Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle. Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of MUSK, the kinase of the complex. The activation of MUSK in myotubes regulates the formation of NMJs through the regulation of different processes including the specific expression of genes in subsynaptic nuclei, the reorganization of the actin cytoskeleton and the clustering of the acetylcholine receptors (AChR) in the postsynaptic membrane. May regulate AChR phosphorylation and clustering through activation of ABL1 and Src family kinases which in turn regulate MUSK. DVL1 and PAK1 that form a ternary complex with MUSK are also important for MUSK-dependent regulation of AChR clustering. May positively regulate Rho family GTPases through FNTA. Mediates the phosphorylation of FNTA which promotes prenylation, recruitment to membranes and activation of RAC1 a regulator of the actin cytoskeleton and of gene expression. Other effectors of the MUSK signaling include DNAJA3 which functions downstream of MUSK. May also play a role within the central nervous system by mediating cholinergic responses, synaptic plasticity and memory formation.
UniProt Q61006
Pathways RTK Signaling, Regulation of Muscle Cell Differentiation

Application Details

Product Details anti-MUSK Antibody Target Details MUSK Handling Images back to top
Application Notes Titration of the Musk antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. IHC (Paraffin): 1:25,Western blot: 1?2000
Restrictions For Research Use only

Handling

Product Details anti-MUSK Antibody Target Details MUSK Application Details Images back to top
Format Liquid
Buffer In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Aliquot the Musk antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

Product Details anti-MUSK Antibody Target Details MUSK Application Details Handling back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-MUSK antibody (Muscle, Skeletal, Receptor Tyrosine Kinase) (ABIN3031880) Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle using Musk an...
Western Blotting (WB) image for anti-MUSK antibody (Muscle, Skeletal, Receptor Tyrosine Kinase) (ABIN3031880) Western blot analysis of lysate from C2C12, L6 cell line (left to right) using Musk a...