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anti-Mouse (Murine) Neuregulin 1 antibody for Enzyme Immunoassay

Recommended Neuregulin 1 Antibody (supplied by: Log in to see )

Antigen
Neuregulin 1 (NRG1) Antibodies
  • 6030402G23Rik
  • ARIA
  • D230005F13Rik
  • DKFZp459A1838
  • GGF
  • GGF2
  • GGFII
  • heregulin
  • HGL
  • Hgl
  • HPRG
  • HRG
  • HRG1
  • HRGA
  • HRGalpha
  • HRGP
  • MST131
  • NDF
  • NRG-1
  • NRG1
  • nrg1-A
  • pro-neuregulin-1
  • SMDF
  • THPH11
  • wu:fm70e01
Reactivity
Human, Mouse (Murine), Rat (Rattus)
174
69
59
2
1
1
1
Host
Rabbit
191
21
Clonality
Polyclonal
Conjugate
This Neuregulin 1 antibody is un-conjugated
18
11
4
3
3
3
2
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
155
91
61
39
19
12
11
10
10
8
5
3
3
2
Supplier
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Catalog No. ABIN265466
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008833851 ABIN783139 EIA IHC (p) WB Rabbit IgG Isoform 10, N-Term Log in to see Polyclonal

Similar anti-Neuregulin 1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 26 Antibodies 22 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 2 Antibodies
Immunochromatography (IC) 2 Antibodies 1 Antibodies
Immunocytochemistry (ICC) 6 Antibodies 3 Antibodies
Immunofluorescence (IF) 3 Antibodies 3 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 12 Antibodies 12 Antibodies
Immunohistochemistry (IHC) 20 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 6 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 17 Antibodies
Immunoprecipitation (IP) 6 Antibodies
Western Blotting (WB) 47 Antibodies

General

Antigen Neuregulin 1 (NRG1) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(174), (69), (59), (2), (1), (1), (1)
Host Rabbit
(191), (21)
Clonality
Polyclonal
Conjugate This Neuregulin 1 antibody is un-conjugated
(18), (11), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(155), (91), (61), (39), (19), (12), (11), (10), (10), (8), (5), (3), (3), (2)
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Product Details anti-Neuregulin 1 Antibody

Target Details Neuregulin 1 Application Details Handling Images
Specificity This antibody detects endogenous levels of SMDF/Neuregulin-1 protein. (region surrounding Tyr4)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity Chromatography using epitope-specific immunogen.

Target Details Neuregulin 1

Product Details anti-Neuregulin 1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Neuregulin 1 (NRG1 Antibody Abstract)
Background The neuregulins are a family of ErbB/HER ligands encoded by four genes. Neuregulin-1 gene, NRG1, encodes numerous splice variants with differing transcription initiation sites. Neuregulin-1 includes a range of isoforms with varying glycosylation, regulation of expression and function. Neuregulin-1 splice variants each bear an EGF-like domain, though otherwise have unique domain structures, differing functions and discrete tissue distribution. Six types of Neuregulin-1 isoform groups have been defined based on their structural features. Three types are most often described, type I (ARIA, NDF or HRG), type II (GGF) and type III (SMDF). Neuregulin-1 has been linked to schizophrenia and has diverse neural functions. Neuregulin-1 affects cell migration, the differentiation of neural crest and Schwann cells, and acts to upregulate the expression of acetylcholine receptors at muscle fibers during the formation of neuromuscular junctions.Synonyms: Acetylcholine receptor-inducing activity, Breast cancer cell differentiation factor p45, GGF, Glial growth factor, HGL, HRG, HRGA, Heregulin, NDF, NRG1, Neu differentiation factor, Pro-neuregulin-1 membrane-bound isoform, SMDF, Sensory and motor neuron-derived factor
Molecular Weight approx. 44.0 kDa
Gene ID 3084
NCBI Accession NP_001153467
UniProt Q02297
Research Area Growth Factors
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-Neuregulin 1 Antibody Target Details Neuregulin 1 Handling Images back to top
Application Notes ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50approx. 1/200Immunofluorescence: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Neuregulin 1 Antibody Target Details Neuregulin 1 Application Details Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-Neuregulin 1 Antibody Target Details Neuregulin 1 Application Details Handling back to top
Supplier Images
 image for anti-Neuregulin 1 antibody (NRG1) (ABIN265466) anti-Neuregulin 1 (NRG1) antibody
 image for anti-Neuregulin 1 antibody (NRG1) (ABIN265466) anti-Neuregulin 1 (NRG1) antibody (Image 2)