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anti-Rat (Rattus) Neuregulin 1 antibody for Immunofluorescence

Recommended Neuregulin 1 Antibody (supplied by: Log in to see )

Antigen
Neuregulin 1 (NRG1) Antibodies
  • 6030402G23Rik
  • ARIA
  • D230005F13Rik
  • DKFZp459A1838
  • GGF
  • GGF2
  • GGFII
  • heregulin
  • HGL
  • Hgl
  • HPRG
  • HRG
  • HRG1
  • HRGA
  • HRGalpha
  • HRGP
  • MST131
  • NDF
  • NRG-1
  • NRG1
  • nrg1-A
  • pro-neuregulin-1
  • SMDF
  • THPH11
  • wu:fm70e01
Reactivity
Human, Mouse (Murine), Rat (Rattus)
198
70
61
2
1
1
1
Host
Rabbit
194
42
Clonality
Polyclonal
Conjugate
This Neuregulin 1 antibody is un-conjugated
19
12
5
4
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
177
110
62
41
19
12
11
10
10
8
5
3
3
2
Supplier
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Catalog No. ABIN265466
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0010840179 ABIN407694 ICC IF IHC (p) IHC WB Rabbit IgG Tyr4 Log in to see Polyclonal
0.0010840179 ABIN3185838 ELISA IF IHC WB Rabbit IgG N-Term Log in to see Polyclonal

Similar anti-Neuregulin 1 Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 26 Antibodies 22 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies 2 Antibodies
Immunochromatography (IC) 2 Antibodies 1 Antibodies
Immunocytochemistry (ICC) 6 Antibodies 3 Antibodies
Immunofluorescence (IF) 3 Antibodies 3 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 12 Antibodies 12 Antibodies
Immunohistochemistry (IHC) 20 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 6 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 18 Antibodies
Immunoprecipitation (IP) 6 Antibodies
Western Blotting (WB) 47 Antibodies

General

Antigen Neuregulin 1 (NRG1) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(198), (70), (61), (2), (1), (1), (1)
Host Rabbit
(194), (42)
Clonality
Polyclonal
Conjugate This Neuregulin 1 antibody is un-conjugated
(19), (12), (5), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(177), (110), (62), (41), (19), (12), (11), (10), (10), (8), (5), (3), (3), (2)
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Product Details anti-Neuregulin 1 Antibody

Target Details Neuregulin 1 Application Details Handling Images
Specificity This antibody detects endogenous levels of SMDF/Neuregulin-1 protein. (region surrounding Tyr4)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity Chromatography using epitope-specific immunogen.

Target Details Neuregulin 1

Product Details anti-Neuregulin 1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Neuregulin 1 (NRG1 Antibody Abstract)
Background The neuregulins are a family of ErbB/HER ligands encoded by four genes. Neuregulin-1 gene, NRG1, encodes numerous splice variants with differing transcription initiation sites. Neuregulin-1 includes a range of isoforms with varying glycosylation, regulation of expression and function. Neuregulin-1 splice variants each bear an EGF-like domain, though otherwise have unique domain structures, differing functions and discrete tissue distribution. Six types of Neuregulin-1 isoform groups have been defined based on their structural features. Three types are most often described, type I (ARIA, NDF or HRG), type II (GGF) and type III (SMDF). Neuregulin-1 has been linked to schizophrenia and has diverse neural functions. Neuregulin-1 affects cell migration, the differentiation of neural crest and Schwann cells, and acts to upregulate the expression of acetylcholine receptors at muscle fibers during the formation of neuromuscular junctions.Synonyms: Acetylcholine receptor-inducing activity, Breast cancer cell differentiation factor p45, GGF, Glial growth factor, HGL, HRG, HRGA, Heregulin, NDF, NRG1, Neu differentiation factor, Pro-neuregulin-1 membrane-bound isoform, SMDF, Sensory and motor neuron-derived factor
Molecular Weight approx. 44.0 kDa
Gene ID 3084
NCBI Accession NP_001153467
UniProt Q02297
Research Area Growth Factors
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-Neuregulin 1 Antibody Target Details Neuregulin 1 Handling Images back to top
Application Notes ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50approx. 1/200Immunofluorescence: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Neuregulin 1 Antibody Target Details Neuregulin 1 Application Details Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-Neuregulin 1 Antibody Target Details Neuregulin 1 Application Details Handling back to top
Supplier Images
 image for anti-Neuregulin 1 antibody (NRG1) (ABIN265466) anti-Neuregulin 1 (NRG1) antibody
 image for anti-Neuregulin 1 antibody (NRG1) (ABIN265466) anti-Neuregulin 1 (NRG1) antibody (Image 2)