You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Human Neuregulin 2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Neuregulin 2 Antibody (supplied by: Log in to see )

Antigen
Neuregulin 2 (NRG2) Antibodies
  • Don1
  • DON1
  • HRG2
  • NRG2
  • Ntak
  • NTAK
  • NTAK_alpha2a
Epitope
AA 358-389, C-Term
14
10
5
4
4
3
2
2
2
1
1
1
1
Reactivity
Human
41
5
3
Host
Rabbit
36
6
Clonality
Polyclonal
Conjugate
This Neuregulin 2 antibody is un-conjugated
4
3
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
28
20
19
3
2
2
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN1882105
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008973577 ABIN1175592 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG AA 101-211 Log in to see Polyclonal
0.0008973577 ABIN4338711 IHC IHC (p) WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-Neuregulin 2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-Neuregulin 2 Antibodies

Application / Reactivity Human
ELISA 27 Antibodies
ELISA (Capture) 1 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunohistochemistry (IHC) 20 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 3 Antibodies
Western Blotting (WB) 18 Antibodies

General

Antigen Neuregulin 2 (NRG2) Antibodies
Epitope AA 358-389, C-Term
(14), (10), (5), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1)
Reactivity Human
(41), (5), (3)
Host Rabbit
(36), (6)
Clonality (Clone)
Polyclonal   ( )
Conjugate This Neuregulin 2 antibody is un-conjugated
(4), (3), (2), (2), (2), (2)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(28), (20), (19), (3), (2), (2), (1)
Pubmed 5 references available
Supplier Log in to see

Product Details anti-Neuregulin 2 Antibody

Target Details Neuregulin 2 Application Details Handling References for anti-Neuregulin 2 Antibody (ABIN1882105) Images
Predicted Reactivity Rat (Rattus)
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. Purified Rabbit Polyclonal Antibody (Pab)
Immunogen This NRG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 358-389 amino acids from the C-terminal region of human NRG2.
Clone RB1278

Target Details Neuregulin 2

Product Details anti-Neuregulin 2 Antibody Application Details Handling References for anti-Neuregulin 2 Antibody (ABIN1882105) Images back to top
Antigen
Alternative Name NRG2 (NRG2 Antibody Abstract)
Background Neuregulin 2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the Erbb family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1 (NRG1), another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. There are six NRG2 alternatively spliced transcripts which are variable between the epidermal growth factor-like (EGF-like) and the transmembrane domains. The gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease.

Synonyms: NRG2, NTAK, Pro-neuregulin-2, membrane-bound isoform, Neuregulin-2, Divergent of neuregulin-1, Neural- and thymus-derived activator for ERBB kinases
NCBI Accession NP_053585, NP_053584, NP_001171864, NP_053586, NP_004874
UniProt O14511
Research Area Signaling, Tyrosine Kinases
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-Neuregulin 2 Antibody Target Details Neuregulin 2 Handling References for anti-Neuregulin 2 Antibody (ABIN1882105) Images back to top
Application Notes IHC (p): 1:50-100
Restrictions For Research Use only

Handling

Product Details anti-Neuregulin 2 Antibody Target Details Neuregulin 2 Application Details References for anti-Neuregulin 2 Antibody (ABIN1882105) Images back to top
Format Liquid
Concentration 1.5 mg/mL
Buffer Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

References for anti-Neuregulin 2 Antibody (ABIN1882105)

Product Details anti-Neuregulin 2 Antibody Target Details Neuregulin 2 Application Details Handling Images back to top
Product cited in:

Yamada, Ichino, Nishii, Sawada, Higashiyama, Ishiguro, Nagatsu: "Characterization of the human NTAK gene structure and distribution of the isoforms for rat NTAK mRNA." in: Gene, Vol. 255, Issue 1, pp. 15-24, 2000

Ring, Chang, Guilbot, Brice, LeGuern, Francke: "The human neuregulin-2 (NRG2) gene: cloning, mapping and evaluation as a candidate for the autosomal recessive form of Charcot-Marie-Tooth disease linked to 5q." in: Human genetics, Vol. 104, Issue 4, pp. 326-32, 1999

Higashiyama, Horikawa, Yamada, Ichino, Nakano, Nakagawa, Miyagawa, Matsushita, Nagatsu, Taniguchi, Ishiguro: "A novel brain-derived member of the epidermal growth factor family that interacts with ErbB3 and ErbB4." in: Journal of biochemistry, Vol. 122, Issue 3, pp. 675-80, 1998

Carraway, Weber, Unger, Ledesma, Yu, Gassmann, Lai: "Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases." in: Nature, Vol. 387, Issue 6632, pp. 512-6, 1997

Busfield, Michnick, Chickering, Revett, Ma, Woolf, Comrack, Dussault, Woolf, Goodearl, Gearing: "Characterization of a neuregulin-related gene, Don-1, that is highly expressed in restricted regions of the cerebellum and hippocampus." in: Molecular and cellular biology, Vol. 17, Issue 7, pp. 4007-14, 1997

Images

Product Details anti-Neuregulin 2 Antibody Target Details Neuregulin 2 Application Details Handling References for anti-Neuregulin 2 Antibody (ABIN1882105) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Neuregulin 2 antibody (NRG2) (AA 358-389) (ABIN1882105) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary ant...