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Browse our Neuregulin 2 Proteins (NRG2)

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Neuregulin 2 Proteins (NRG2)
On are 14 Neuregulin 2 (NRG2) Proteins from 6 different suppliers available. Additionally we are shipping Neuregulin 2 Antibodies (43) and Neuregulin 2 Kits (18) and many more products for this protein. A total of 75 Neuregulin 2 products are currently listed.
DON1, HRG2, NRG2, Ntak, NTAK_alpha2a
list all proteins Gene Name GeneID UniProt
NRG2 100042150  
NRG2 9542 O14511
NRG2 432361 O35569

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Neuregulin 2 Proteins (NRG2) by Origin

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More Proteins for Neuregulin 2 Interaction Partners

Mouse (Murine) Neuregulin 2 (NRG2) interaction partners

  1. Findings reveal an intimate reciprocal relationship between ErbB4 (show ERBB4 Proteins) and GluN2b (show GRIN2B Proteins) NMDA receptors via NRG2/ErbB4 (show ERBB4 Proteins) signaling.

  2. The distinct temporal, regional, and subcellular expression of NRG-2 in the developing brain suggests its unique and nonredundant role in neural function.

  3. in vivo NRG-2 activity differs substantially from that of NRG-1 (show NRG1 Proteins), and it is not essential for normal development

  4. identify NRG2 as a factor capable of promoting subventricular zone proliferation, leading to the formation of new neurons in vivo

Human Neuregulin 2 (NRG2) interaction partners

  1. reduced expression of NRG2 led to marginal increase in cell survival under arsenite-induced stress.

  2. Nrg-2-induced Acetylcholine Receptor transcription requires an N-box motif and is regulated by alternative splicing.

  3. Linkage interval for GLC1M (show EFNA5 Proteins) was refined to a smaller region. The NRG2 gene was excluded as the causative gene for juvenile-onset primary open angle glaucoma.

  4. Gln43 of NRG2beta is both necessary and sufficient for NRG2 stimulation of ErbB4 (show ERBB4 Proteins) coupling to IL3 (show Il3 Proteins) independence.

  5. NRG2 was positive in almost all breast cancers studied. High expression is related to the biological aggressiveness of breast cancer.

Neuregulin 2 (NRG2) Protein Profile

Protein Summary

This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with Neuregulin 2 (NRG2)

  • neuregulin 2 (NRG2)
  • neuregulin 2 (Nrg2)
  • neuregulin 2 (LOC100345149)
  • DON1 protein
  • HRG2 protein
  • NRG2 protein
  • Ntak protein
  • NTAK_alpha2a protein

Protein level used designations for Neuregulin 2 Proteins (NRG2)

neuregulin 2 , pro-NRG2 , pro-neuregulin-2, membrane-bound isoform , divergent of neuregulin-1 , neural- and thymus-derived activator for ErbB kinases , NTAK alpha1

471648 Pan troglodytes
487158 Canis lupus familiaris
100042150 Mus musculus
9542 Homo sapiens
432361 Rattus norvegicus
427606 Gallus gallus
100345149 Oryctolagus cuniculus
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