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anti-Human Neuregulin 3 antibody for Enzyme Immunoassay

Recommended Neuregulin 3 Antibody (supplied by: Log in to see )

Antigen
Neuregulin 3 (NRG3) Antibodies
  • HRG3
  • NRG3
  • pro-NRG3
  • RGD1559678
  • ska
Reactivity
Human
66
30
24
3
1
1
1
1
1
1
Host
Rabbit
51
18
Clonality
Polyclonal
Conjugate
This Neuregulin 3 antibody is un-conjugated
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
38
34
28
11
11
Supplier
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Catalog No. ABIN302658
$ 500.50
Plus shipping costs $45.00

Similar anti-Neuregulin 3 Antibodies

Application / Reactivity Human
ELISA 37 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies
Immunohistochemistry (IHC) 25 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 11 Antibodies
Western Blotting (WB) 31 Antibodies

General

Antigen Neuregulin 3 (NRG3) Antibodies
Reactivity Human
(66), (30), (24), (3), (1), (1), (1), (1), (1), (1)
Host Rabbit
(51), (18)
Clonality
Polyclonal
Conjugate This Neuregulin 3 antibody is un-conjugated
(4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(38), (34), (28), (11), (11)
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Product Details anti-Neuregulin 3 Antibody

Target Details Neuregulin 3 Application Details Handling Images
Specificity This antibody detects Neuregulin-3 (NRG-3/NRG3).
Purification Purified
Immunogen Synthetic peptide of Neuregulin-3 (NRG-3/NRG3) - KLH conjugated

Target Details Neuregulin 3

Product Details anti-Neuregulin 3 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Neuregulin 3 (NRG3 Antibody Abstract)
Background NRG3, which belongs to the neuregulin family, is a direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand stimulated tyrosine phosphorylation and activation of the receptor. NRG3 does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. The protein exists as an type I membrane protein and as a proteolytically released soluble growth factor form. The membrane-bound form does not appear to be active. NRG3 is highly expressed in most regions of the brain with the exception of corpus callosum, and is expressed at lower level in testis. It is not detected in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, ovary, small intestine, colon and peripheral blood leukocytes. The NRG3 cytoplasmic domain may be involved in the regulation of trafficking and proteolytic processing. Regulation of the proteolytic processing may involve initial intracellular domain dimerization. There are 4 different isoforms.Synonyms: NRG3, Pro-NRG3, Pro-neuregulin-3, membrane-bound isoform
Gene ID 10718
NCBI Accession NP_001010848
UniProt P56975
Pathways RTK Signaling

Application Details

Product Details anti-Neuregulin 3 Antibody Target Details Neuregulin 3 Handling Images back to top
Application Notes Immunohistochemistry on paraffin sections (20 μg/mL). ELISA (1: 0 - 1: 1000). Antigen retrieval: Steam slides in 0.01 M sodium citrate buffer, pH 6.0, at 99-100C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Neuregulin 3 Antibody Target Details Neuregulin 3 Application Details Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline containing 0.09 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice DO NOT FREEZE!!
Storage 4 °C

Images

Product Details anti-Neuregulin 3 Antibody Target Details Neuregulin 3 Application Details Handling back to top
Supplier Images
 image for anti-Neuregulin 3 antibody (NRG3) (ABIN302658) anti-Neuregulin 3 (NRG3) antibody