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anti-Mouse (Murine) NFAT1 antibody for Immunoprecipitation

Recommended NFAT1 Antibody (supplied by: Log in to see )

Antigen
Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) Antibodies
  • AI607462
  • NF-ATc2
  • NFAT1
  • NFAT1-D
  • NFATC2
  • NFATP
  • Nfatp
Epitope
AA 433-567
33
15
13
7
7
6
4
3
3
2
2
2
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
123
56
50
7
3
2
1
1
1
Host
Mouse
98
17
12
Clonality
Monoclonal
Conjugate
This NFAT1 antibody is un-conjugated
6
6
6
3
3
3
3
3
3
3
3
3
3
3
3
Application
Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
71
41
33
20
19
13
9
5
3
2
2
1
1
1
Supplier
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Catalog No. ABIN967558
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089235755 ABIN152663 GS ICC IF IHC (p) IP IHC ELISA WB Mouse IgG1 AA 51-69 Log in to see 25A10-D6-D2 2
0.00089235755 ABIN2324787 IC IP WB Mouse IgG1 AA 51-69 Log in to see 6D607

Top referenced anti-NFAT1 antibody for Immunoprecipitation

Similar anti-NFAT1 Antibodies

Application / Reactivity Mouse (Murine) Human
ELISA 5 Antibodies 41 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies 2 Antibodies
Gel Shift (GS) 1 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 1 Antibodies
Immunofluorescence (IF) 3 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 33 Antibodies
Immunohistochemistry (IHC) 4 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 12 Antibodies
Immunoprecipitation (IP) 3 Antibodies
Western Blotting (WB) 26 Antibodies
Chromatin Immunoprecipitation (ChIP) 1 Antibodies
Dot Blot (DB) 19 Antibodies
ELISA (Capture) 1 Antibodies

General

Antigen Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) Antibodies
Epitope AA 433-567
(33), (15), (13), (7), (7), (6), (4), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(123), (56), (50), (7), (3), (2), (1), (1), (1)
Host Mouse
(98), (17), (12)
Clonality (Clone)
Monoclonal   ( )
Conjugate This NFAT1 antibody is un-conjugated
(6), (6), (6), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3)
Application Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
(71), (41), (33), (20), (19), (13), (9), (5), (3), (2), (2), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-NFAT1 Antibody

Target Details NFAT1 Application Details Handling References for anti-NFAT1 Antibody (ABIN967558) Images
Brand BD Pharmingen™
Cross-Reactivity Mouse (Murine)
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
3. Please refer to us for technical protocols.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Human NF-ATc2 aa. 433-567 Peptide
Clone 4G6-G5
Isotype IgG2a, kappa

Target Details NFAT1

Product Details anti-NFAT1 Antibody Application Details Handling References for anti-NFAT1 Antibody (ABIN967558) Images back to top
Antigen
Alternative Name NF-ATc2 (NFAT1 Antibody Abstract)
Background The NF-AT family of transcription factors are regulators of early immune response genes in T cells following their activation by CD40L, FasL and interleukins including IL-2, -3, -4 and -5. NF-AT proteins function in both signal transduction and transcription control. The DNA binding, active NF-AT complex contains a cytoplasmic, Ca2+/calcineurin dependent, cyclosporin sensitive subunit, designated NF-ATc, which is present in the cytoplasm of resting cells. Upon cell activation, NF-ATc is dephosphorylated and thus activated by calcineurin, resulting in rapid translocation of NF-ATc to the nucleus. The active NF-AT complex also contains a nuclear component, designated NF-ATn. In vitro, NF-AT cooperates with the mitogenic transcription factor AP-1 to induce multiple cytokine genes. NF-ATc is encoded by four genes: NF-ATc1 (originally named NF-ATc), NF-ATc2 (originally named NF-ATp), NF-ATc3 (NF-AT3), and NF-ATc4 (NF-AT4). These proteins are differentially expressed in tissues, suggesting that each may activate distinct sets of genes. NF-ATc2 is constutively expressed in resting immune cells. NF-ATc2 is required for the development of Th2 responses and plays a role in the production of IL-4.
Synonyms: NFAT1, NFATP, KIAA0611
Molecular Weight 97-135 kDa
Pathways RTK Signaling, WNT Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-NFAT1 Antibody Target Details NFAT1 Handling References for anti-NFAT1 Antibody (ABIN967558) Images back to top
Comment

Related Products: ABIN968537, ABIN967389, ABIN968123

Restrictions For Research Use only

Handling

Product Details anti-NFAT1 Antibody Target Details NFAT1 Application Details References for anti-NFAT1 Antibody (ABIN967558) Images back to top
Format Liquid
Concentration 0.5 mg/mL
Buffer Aqueous buffered solution containing ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store undiluted at 4°C.

References for anti-NFAT1 Antibody (ABIN967558)

Product Details anti-NFAT1 Antibody Target Details NFAT1 Application Details Handling Images back to top
Product cited in:

Xanthoudakis, Viola, Shaw, Luo, Wallace, Bozza, Luk, Curran, Rao: "An enhanced immune response in mice lacking the transcription factor NFAT1." in: Science (New York, N.Y.), Vol. 272, Issue 5263, pp. 892-5, 1996

Crabtree: "Contingent genetic regulatory events in T lymphocyte activation." in: Science (New York, N.Y.), Vol. 243, Issue 4889, pp. 355-61, 1989

Images

Product Details anti-NFAT1 Antibody Target Details NFAT1 Application Details Handling References for anti-NFAT1 Antibody (ABIN967558) back to top
Supplier Images
Western Blotting (WB) image for anti-NFAT1 antibody (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2) (AA 433-567) (ABIN967558) Western blot analysis of NF-ATc2. A Jurkat cell lysate (Human T-cell leukemia, ATCC T...
 image for anti-NFAT1 antibody (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2) (AA 433-567) (ABIN967558) anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) (AA 433-567) antibody (Image 2)
Western Blotting (WB) image for anti-NFAT1 antibody (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2) (AA 433-567) (ABIN967558) anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1) (AA 433-567) antibody (Image 3)