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Browse our anti-NFATC1 (NFATC1) Antibodies

Full name:
anti-Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 Antibodies (NFATC1)
On www.antibodies-online.com are 123 Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) Antibodies from 24 different suppliers available. Additionally we are shipping NFATC1 Kits (13) and NFATC1 Proteins (5) and many more products for this protein. A total of 151 NFATC1 products are currently listed.
Synonyms:
2210017P03Rik, AI449492, AV076380, NF-ATC, NF-ATc1, NFAT, NFAT2, NFATc, NFATC1, Nfatcb, NFATmac, si:ch211-198c22.2
list all antibodies Gene Name GeneID UniProt
NFATC1 18018  
NFATC1 4772 O95644
NFATC1 100361818  

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Top referenced anti-NFATC1 Antibodies

  1. Human Monoclonal NFATC1 Primary Antibody for IF, IP - ABIN967559 : Crabtree: Contingent genetic regulatory events in T lymphocyte activation. in Science (New York, N.Y.) 1989 (PubMed)
    Show all 5 references for ABIN967559

  2. Human Monoclonal NFATC1 Primary Antibody for EIA, IHC (p) - ABIN336112 : Akimzhanov, Krenacs, Schlegel, Klein-Hessling, Bagdi, Stelkovics, Kondo, Chuvpilo, Wilke, Avots, Gattenlöhner, Müller-Hermelink, Palmetshofer, Serfling: Epigenetic changes and suppression of the nuclear factor of activated T cell 1 (NFATC1) promoter in human lymphomas with defects in immunoreceptor signaling. in The American journal of pathology 2008 (PubMed)
    Show all 2 references for ABIN336112

  3. Human Polyclonal NFATC1 Primary Antibody for IHC, ELISA - ABIN1450275 : Northrop, Ho, Chen, Thomas, Timmerman, Nolan, Admon, Crabtree: NF-AT components define a family of transcription factors targeted in T-cell activation. in Nature 1994 (PubMed)

  4. Dog (Canine) Polyclonal NFATC1 Primary Antibody for WB - ABIN2778553 : Crotti, Sharma, Fleming, Flannery, Ostrowski, Goldring, McHugh: PU.1 and NFATc1 mediate osteoclastic induction of the mouse beta3 integrin promoter. in Journal of cellular physiology 2008 (PubMed)

  5. Human Polyclonal NFATC1 Primary Antibody for IHC (p), WB - ABIN657821 : Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: New genetic associations detected in a host response study to hepatitis B vaccine. in Genes and immunity 2010 (PubMed)

  6. Human Polyclonal NFATC1 Primary Antibody for WB - ABIN2780748 : Kumar, Manning, Spendlove, Kremmidiotis, McKirdy, Lee, Millband, Cheney, Stampfer, Dwivedi, Morris, Callen: ZNF652, a novel zinc finger protein, interacts with the putative breast tumor suppressor CBFA2T3 to repress transcription. in Molecular cancer research : MCR 2006 (PubMed)

More Antibodies against NFATC1 Interaction Partners

Mouse (Murine) Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) interaction partners

  1. Nfatc1 enhances the expression of genes involved in DMBA metabolism and increases DMBA-induced DNA damage in keratinocytes. Data implicate Nfatc1 in the regulation of skin stem cell-initiated tumorigenesis via the regulation of DMBA metabolism.

  2. Adseverin (show SCIN Antibodies) knockdown also suppressed the RANKL (show TNFSF11 Antibodies)-mediated induction of nuclear factor of activated T-cell (show NFATC3 Antibodies) c1 (NFATc1), which is a key transcription factor in osteoclastogenesis.

  3. Upon binding to a composite NFAT/BCL6 (show BCL6 Antibodies) regulatory element within the Ccl2 (show CCL2 Antibodies) promoter, NFATc1/beta proteins release the BCL6 (show BCL6 Antibodies)-dependent repression of Ccl2 (show CCL2 Antibodies) gene in macrophages.

  4. COX-2 (show COX2 Antibodies) expression in the kidney but not other regions colocalized with nuclear factor of activated T cells (NFAT) transcription factor activity and was sensitive to inhibition of calcineurin (show PPP3CA Antibodies)-dependent NFAT activation.

  5. Tmem178 localizes to the ER membrane and regulates RANKL (show TNFSF11 Antibodies)-induced Ca(2 (show CA2 Antibodies)+) fluxes, thus controlling NFATc1 induction

  6. Taken together, our findings demonstrate that salicortin inhibits NF-kappaB (show NFKB1 Antibodies) and NFATc1 activation, leading to attenuation of osteoclastogenesis and bone resorption.

  7. Data suggest BMP2 (bone morphogenetic protein 2 (show BMP2 Antibodies)) up-regulates calcium release from intracellular stores, Smad5 (show SMAD5 Antibodies)/PI3K/Akt (show AKT1 Antibodies) signaling, and NFATc1 (NFAT calcineurin (show PPP3CA Antibodies)-dependent 1 protein) expression/dephosphorylation by calcineurin (show PPP3CA Antibodies)/nuclear translocation.

  8. Regulation of osteoclast genes and NFATc1 by LPS (show TLR4 Antibodies)-PG and IL-1 (show IL1A Antibodies) is dependent on MyD88 (show MYD88 Antibodies), an important signaling adaptor for both TLR and IL-1R family members

  9. that alternative N-terminal domains of NFAT2 could provide differential mechanisms for the control of cellular functions

  10. Targeting NFATc1 in T lymphocytes ameliorated the allergic trait in the airways of NFATc1(fl/fl (show FLT3LG Antibodies)) xCD4Cre mice.

Human Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) interaction partners

  1. NFATc1binds the GLI1 (show GLI1 Antibodies) promoter and represses its transcription.

  2. InB may exhibit growth-inhibitory activity through the activation of PKCalpha (show PKCa Antibodies), followed by an increase in NFAT transactivation ability.

  3. The low socioeconomic status (SES) were associated with DNA methylation (show HELLS Antibodies) of genes involved in inflammation. NFATC1, in particular, was consistently found to be less methylated in individuals with low vs high SES, in a dose-dependent manner.

  4. Synergistic interactions between NFAT and Foxp3 (show FOXP3 Antibodies) determine Treg-specific GARP (show CNGB1 Antibodies) expression.

  5. Tmem178 localizes to the ER membrane and regulates RANKL (show TNFSF11 Antibodies)-induced Ca(2 (show CA2 Antibodies)+) fluxes, thus controlling NFATc1 induction

  6. DDIAS is a target of NFATc1 and is associated with cisplatin resistance in lung cancer cells.

  7. that alternative N-terminal domains of NFAT2 could provide differential mechanisms for the control of cellular functions

  8. This study suggested that development of specific NFAT inhibitors may offer promise as an effective strategy for attenuating the microgliosis and Abeta (show APP Antibodies) plaque deposition that occur in Alzheimer's disease.

  9. NFATc1 participation in osteogenic differentiation through its direct involvement in the regulatory machinery of mitochondria suggests a new role for this transcription factor.

  10. A channel chimera of Orai3 (show ORAI3 Antibodies) with the N terminus of Orai1 (show ORAI1 Antibodies) was able to couple local Ca(2 (show CA2 Antibodies)+) entry to NFAT activation, identifying the N-terminal domain of Orai1 (show ORAI1 Antibodies) as central to Ca(2 (show CA2 Antibodies)+) nanodomain-transcription coupling.

Cow (Bovine) Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) interaction partners

  1. In calf pulmonary artery endothelial cells, extracellular application of vasoactive agonist ATP or calcium ionophore ionomycin generates a rise in intracellular calcium that induces nuclear localization of NFATc1.

  2. regulation of nuclear localization of NFAT is isoform-specific and dependent on nuclear export processes

NFATC1 Antigen Profile

Antigen Summary

The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

Alternative names and synonyms associated with NFATC1

  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (NFATC1) antibody
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (nfatc1) antibody
  • nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 (Nfatc1) antibody
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (Nfatc1) antibody
  • 2210017P03Rik antibody
  • AI449492 antibody
  • AV076380 antibody
  • NF-ATC antibody
  • NF-ATc1 antibody
  • NFAT antibody
  • NFAT2 antibody
  • NFATc antibody
  • NFATC1 antibody
  • Nfatcb antibody
  • NFATmac antibody
  • si:ch211-198c22.2 antibody

Protein level used designations for NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 , nuclear factor of activated T-cells, cytosolic component 1 , nuclear factor of activated T-cells calcineurin-dependent 1 , nuclear factor of activated T-cells, cytoplasmic 1 , nuclear factor of activated T-cells, cytoplasmic 1-like , NF-ATc1 , NFAT transcription complex cytosolic component , transcription factor NF-ATc , NFATc , transcription factor NFATmac

GENE ID SPECIES
420815 Gallus gallus
444346 Xenopus laevis
455485 Pan troglodytes
568315 Danio rerio
698089 Macaca mulatta
780197 Xenopus (Silurana) tropicalis
100023153 Monodelphis domestica
100065378 Equus caballus
100436209 Pongo abelii
100470861 Ailuropoda melanoleuca
100545778 Meleagris gallopavo
100565300 Anolis carolinensis
18018 Mus musculus
4772 Homo sapiens
100361818 Rattus norvegicus
483925 Canis lupus familiaris
511224 Bos taurus
397318 Sus scrofa
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