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Browse our NFATC1 Proteins (NFATC1)

Full name:
Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 Proteins (NFATC1)
On www.antibodies-online.com are 5 Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) Proteins from 4 different suppliers available. Additionally we are shipping NFATC1 Antibodies (147) and NFATC1 Kits (13) and many more products for this protein. A total of 175 NFATC1 products are currently listed.
Synonyms:
2210017P03Rik, AI449492, AV076380, NF-ATC, NF-ATc1, NFAT, NFAT2, NFATc, NFATC1, Nfatcb, NFATmac, si:ch211-198c22.2
list all proteins Gene Name GeneID UniProt
NFATC1 18018  
NFATC1 4772 O95644
Rat NFATC1 NFATC1 100361818  

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NFATC1 Proteins (NFATC1) by Origin

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More Proteins for NFATC1 Interaction Partners

Mouse (Murine) Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) interaction partners

  1. these results suggested that piperine inhibited osteoclast differentiation by suppressing the p38/NFATc1/c-Fos signaling axis

  2. Data show that TGFbeta (show TGFB1 Proteins)-activated kinase-1 (TAK1 (show NR2C2 Proteins)) activated nuclear factor of activated T-cells (NFAT)/NF-kappa B (NFkappaB (show NFKB1 Proteins)), downregulated BCL2-adenovirus E1B interacting protein 3 (Bnip3 (show BNIP3 Proteins)), and inhibited cardiac cell death.

  3. Stabilized HIF-1alpha (show HIF1A Proteins) induced by PHD2 (show EGLN1 Proteins) conditional knockout resulted in the transition of muscle fibers toward a slow fiber type via a calcineurin (show PPP3CA Proteins)/NFATc1 signaling pathway.

  4. Insulin (show INS Proteins) significantly activated ERK1/2 MAP kinase (show MAPK1 Proteins) as well as markedly induced the expression of NFATc1, an osteoclast marker gene, and Atp6v0d2 (show ATP6V0D2 Proteins), an osteoclast fusion-related gene.

  5. CD137 (show TNFRSF9 Proteins) Regulates NFATc1 Expression in Mouse VSMCs through TRAF6 (show TRAF6 Proteins)/NF-kappaB (show NFKB1 Proteins) p65 (show NFkBP65 Proteins) Signaling Pathway.

  6. Data show that segregation of Foxc2 (show FOXC2 Proteins) and NFATc1 transcription factor is closely associated with the highly polarized expression of connexins Cx37 (show GJA4 Proteins), Cx43 (show GJA1 Proteins), and Cx47 (show GJC2 Proteins).

  7. Findings suggest that RANKL protein-induced lactate dehydrogenase (LDH) activation stimulates glycolytic and mitochondrial respiratory metabolism via transcription factor NFATc1 signaling.

  8. Nfatc1 enhances the expression of genes involved in DMBA metabolism and increases DMBA-induced DNA damage in keratinocytes. Data implicate Nfatc1 in the regulation of skin stem cell-initiated tumorigenesis via the regulation of DMBA metabolism.

  9. Adseverin (show SCIN Proteins) knockdown also suppressed the RANKL (show TNFSF11 Proteins)-mediated induction of nuclear factor of activated T-cell (show NFATC3 Proteins) c1 (NFATc1), which is a key transcription factor in osteoclastogenesis.

  10. Upon binding to a composite NFAT/BCL6 (show BCL6 Proteins) regulatory element within the Ccl2 (show CCL2 Proteins) promoter, NFATc1/beta proteins release the BCL6 (show BCL6 Proteins)-dependent repression of Ccl2 (show CCL2 Proteins) gene in macrophages.

Human Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) interaction partners

  1. Data indicate that RNA interference of NFAT isoforms NFATc1, NFATc2 (show NFAT1 Proteins), NFATc3 (show NFATC3 Proteins) and NFATc4 (show NFATC4 Proteins) regulate gene expression differentially in human retinal microvascular endothelial cells (HRMEC).

  2. NFATc1binds the GLI1 (show GLI1 Proteins) promoter and represses its transcription.

  3. InB may exhibit growth-inhibitory activity through the activation of PKCalpha (show PKCa Proteins), followed by an increase in NFAT transactivation ability.

  4. The low socioeconomic status (SES) were associated with DNA methylation (show HELLS Proteins) of genes involved in inflammation. NFATC1, in particular, was consistently found to be less methylated in individuals with low vs high SES, in a dose-dependent manner.

  5. Synergistic interactions between NFAT and Foxp3 (show FOXP3 Proteins) determine Treg-specific GARP (show CNGB1 Proteins) expression.

  6. Tmem178 localizes to the ER membrane and regulates RANKL (show TNFSF11 Proteins)-induced Ca(2 (show CA2 Proteins)+) fluxes, thus controlling NFATc1 induction

  7. DDIAS is a target of NFATc1 and is associated with cisplatin resistance in lung cancer cells.

  8. that alternative N-terminal domains of NFAT2 could provide differential mechanisms for the control of cellular functions

  9. This study suggested that development of specific NFAT inhibitors may offer promise as an effective strategy for attenuating the microgliosis and Abeta (show APP Proteins) plaque deposition that occur in Alzheimer's disease.

  10. NFATc1 participation in osteogenic differentiation through its direct involvement in the regulatory machinery of mitochondria suggests a new role for this transcription factor.

Cow (Bovine) Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 1 (NFATC1) interaction partners

  1. In calf pulmonary artery endothelial cells, extracellular application of vasoactive agonist ATP or calcium ionophore ionomycin generates a rise in intracellular calcium that induces nuclear localization of NFATc1.

  2. regulation of nuclear localization of NFAT is isoform-specific and dependent on nuclear export processes

NFATC1 Protein Profile

Protein Summary

The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

Alternative names and synonyms associated with NFATC1

  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (NFATC1)
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (nfatc1)
  • nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 (Nfatc1)
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 (Nfatc1)
  • 2210017P03Rik protein
  • AI449492 protein
  • AV076380 protein
  • NF-ATC protein
  • NF-ATc1 protein
  • NFAT protein
  • NFAT2 protein
  • NFATc protein
  • NFATC1 protein
  • Nfatcb protein
  • NFATmac protein
  • si:ch211-198c22.2 protein

Protein level used designations for NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 , nuclear factor of activated T-cells, cytosolic component 1 , nuclear factor of activated T-cells calcineurin-dependent 1 , nuclear factor of activated T-cells, cytoplasmic 1 , nuclear factor of activated T-cells, cytoplasmic 1-like , NF-ATc1 , NFAT transcription complex cytosolic component , transcription factor NF-ATc , NFATc , transcription factor NFATmac

GENE ID SPECIES
420815 Gallus gallus
444346 Xenopus laevis
455485 Pan troglodytes
568315 Danio rerio
698089 Macaca mulatta
780197 Xenopus (Silurana) tropicalis
100023153 Monodelphis domestica
100065378 Equus caballus
100436209 Pongo abelii
100470861 Ailuropoda melanoleuca
100545778 Meleagris gallopavo
100565300 Anolis carolinensis
18018 Mus musculus
4772 Homo sapiens
100361818 Rattus norvegicus
483925 Canis lupus familiaris
511224 Bos taurus
397318 Sus scrofa
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