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Browse our NFATC3 Proteins (NFATC3)

Full name:
Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3 Proteins (NFATC3)
On www.antibodies-online.com are 5 Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3 (NFATC3) Proteins from 3 different suppliers available. Additionally we are shipping NFATC3 Antibodies (47) and NFATC3 Kits (5) and many more products for this protein. A total of 63 NFATC3 products are currently listed.
Synonyms:
C80703, D8Ertd281e, nf-at, NFAT4, NFATC3, NFATX
list all proteins Gene Name GeneID UniProt
NFATC3 18021  
NFATC3 4775 Q12968
Rat NFATC3 NFATC3 361400  

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NFATC3 Proteins (NFATC3) by Origin

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Cow (Bovine) Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3 (NFATC3) interaction partners

  1. regulation of nuclear localization of NFAT (show NFATC1 Proteins) is isoform-specific and dependent on nuclear export processes

Mouse (Murine) Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3 (NFATC3) interaction partners

  1. Study defines the NFAT4/ miR (show MLXIP Proteins)-324-5p/Mtfr1 (show MTFR1 Proteins) axis, which participates in the regulation of mitochondrial fission and cardiomyocyte apoptosis.

  2. Disrupting the calcineurin (show PPP3CA Proteins)-NFAT (show NFATC1 Proteins) axis by either genetic or pharmacologic approaches confers resistance to the development of social stress-induced voiding and dysfunction.

  3. NFATc3 interacted in a SUMO-dependent manner with Trim17 (show TRIM17 Proteins), an E3 ubiquitin ligase (show MUL1 Proteins) necessary for neuronal apoptosis

  4. A calcineurin- and NFAT-dependent pathway is involved in alpha-synuclein-induced degeneration of midbrain dopaminergic neurons in a Parkinson's disease mouse model.

  5. study demonstrates for the first time that NFATc3 is necessary for macrophage iNOS (show NOS2 Proteins) expression during sepsis, which is essential for containment of bacterial infections.

  6. GRK5 (show GRK5 Proteins), acting in a kinase independent manner, is a facilitator of NFAT (show NFATC1 Proteins) activity and part of a DNA-binding complex responsible for pathological hypertrophic gene transcription.

  7. Low intracellular hydrogen peroxide contributes to NFATc3 activation in pulmonary arterial smooth muscle.

  8. NGF (show NGFB Proteins) facilitates depolarization-induced NFAT (show NFATC1 Proteins) activation by stimulating PI3K/Akt (show AKT1 Proteins) signaling, inactivating GSK3beta, and thereby slowing NFATc3 export from the nucleus

  9. Toxoplasma GRA6-dependent NFAT4 activation is required for T. gondii manipulation of host immune responses to maximize the parasite virulence in a strain-dependent manner.

  10. this study demonistrated that NFATc3 promotes Ca(2 (show CA2 Proteins)+) -dependent MMP3 (show MMP3 Proteins) expression in astroglial cells in mice.

Human Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3 (NFATC3) interaction partners

  1. two NFAT isoforms (NFAT4 and NFAT1) have shifted band-pass windows for the same receptor in the GPCR signaling pathway

  2. Data indicate that RNA interference of NFAT (show NFATC1 Proteins) isoforms NFATc1 (show NFATC1 Proteins), NFATc2 (show NFAT1 Proteins), NFATc3 and NFATc4 (show NFATC4 Proteins) regulate gene expression differentially in human retinal microvascular endothelial cells (HRMEC).

  3. NFATc3 interacted in a SUMO-dependent manner with Trim17 (show TRIM17 Proteins), an E3 ubiquitin ligase (show MUL1 Proteins) necessary for neuronal apoptosis

  4. Results show that two protein isoforms NFAT1 (show NFAT1 Proteins) and NFAT4 are both cytosolic and stimulated by the same Ca2 (show CA2 Proteins)+ messenger but require distinct subcellular Ca2 (show CA2 Proteins)+ signals for activity.

  5. Suggest nuclear NF-AT3 (show NFATC4 Proteins) and NF-AT4 participates in atrial structural remodeling, and that PICP and TGF-beta1 (show TGFB1 Proteins) levels may be sensitive serum biomarkers to estimate atrial structural remodeling with atrial fibrillation.

  6. Microvesicles from tumor cells transferred TrpC5 (show TRPC5 Proteins) to endothelial cells, inducing the expression of P-glycoprotein by activation of the transcription factor NFATc3 (nuclear factor of activated T cells isoform c3).

  7. AP-1 (show FOSB Proteins) and NFAT4 complex promotes miR (show MLXIP Proteins)-23a expression.

  8. The closely related transcription factors NFAT1 (show NFAT1 Proteins) and NFAT4 possess distinct nuclear localization dynamics in response to cell stimulation.

  9. Data indicate that NFATc3 undergoes rapid dephosphorylation and nuclear translocation that are essentially complete within 20 min, although NFATc4 (show NFATC4 Proteins) remains phosphorylated and localized to the cytosol.

  10. Abeta (show APP Proteins)-activated NFAT4 proteins were associated with astrocytic BACE1 (show BACE Proteins) gene expression via direct interaction with the BACE1 (show BACE Proteins) promoter region.

Xenopus laevis Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 3 (NFATC3) interaction partners

  1. NF-AT affects neural convergent extension.

  2. transcriptional control of morphological and electrophysiological properties of neurons is mediated by distinct NFAT (show NFATC1 Proteins) interactions

NFATC3 Protein Profile

Protein Summary

The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene.

Alternative names and synonyms associated with NFATC3

  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 (NFATC3)
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 (nfatc3)
  • nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 (Nfatc3)
  • nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 (Nfatc3)
  • C80703 protein
  • D8Ertd281e protein
  • nf-at protein
  • NFAT4 protein
  • NFATC3 protein
  • NFATX protein

Protein level used designations for NFATC3

cytoplasmic nuclear factor of activated T-cells 3 , nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 , nuclear factor of activated T-cells, cytoplasmic 3 , nuclear factor of activated T-cells, cytoplasmic 3-like , NF-AT4 , NF-ATc3 , T-cell transcription factor NFAT4 , T cell transcription factor NFAT4 , nuclear factor of activated T-cells c3 isoform IE-Xa , nuclear factor of activated T-cell

GENE ID SPECIES
415711 Gallus gallus
454184 Pan troglodytes
479678 Canis lupus familiaris
541127 Bos taurus
702390 Macaca mulatta
100021991 Monodelphis domestica
100216091 Xenopus (Silurana) tropicalis
100458008 Pongo abelii
100477832 Ailuropoda melanoleuca
100545688 Meleagris gallopavo
100561893 Anolis carolinensis
100605649 Nomascus leucogenys
18021 Mus musculus
4775 Homo sapiens
398297 Xenopus laevis
361400 Rattus norvegicus
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