anti-Cow (Bovine) NTRK3 antibody for Western Blotting

Recommended NTRK3 Antibody (supplied by: Log in to see )

Antigen
Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) Antibodies
  • TRKC
  • gp145(trkC)
  • AW125844
  • Ntrk3_tv3
  • TrkC
  • trkC
  • neurotrophic tyrosine kinase, receptor, type 3
  • NTRK3
  • LOC100227403
  • Ntrk3
Epitope
C-Term
38
22
18
14
10
8
8
8
8
5
5
4
4
3
3
3
3
3
3
3
3
2
2
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Zebrafish
184
87
50
4
3
2
1
1
1
1
1
Host
Rabbit
118
73
16
15
6
Clonality
Polyclonal
Conjugate
This NTRK3 antibody is un-conjugated
10
5
5
4
4
4
4
4
4
4
3
3
3
1
1
1
1
1
1
1
Application
Western Blotting (WB)
168
89
79
32
28
14
8
4
3
2
2
1
1
1
1
1
1
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Catalog No. ABIN2784511
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2626398 IHC WB Rabbit IgG AA 172-186 Log in to see Polyclonal

General

Antigen Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) Antibodies
Epitope C-Term
(38), (22), (18), (14), (10), (8), (8), (8), (8), (5), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Guinea Pig, Horse (Equine), Human, Mouse (Murine), Pig (Porcine), Rabbit, Rat (Rattus), Zebrafish
(184), (87), (50), (4), (3), (2), (1), (1), (1), (1), (1)
Host Rabbit
(118), (73), (16), (15), (6)
Clonality
Polyclonal
Conjugate This NTRK3 antibody is un-conjugated
(10), (5), (5), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1)
Application Western Blotting (WB)
(168), (89), (79), (32), (28), (14), (8), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Product Details anti-NTRK3 Antibody

Target Details NTRK3 Application Details Handling References for anti-NTRK3 antibody (ABIN2784511) Images
Blocking Peptide Blocking peptide for this product available: ABIN981001
Sequence ERPRVCPKEV YDVMLGCWQR EPQQRLNIKE IYKILHALGK ATPIYLDILG
Predicted Reactivity Cow: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%
Characteristics This is a rabbit polyclonal antibody against NTRK3. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human NTRK3

Target Details NTRK3

Product Details anti-NTRK3 Antibody Application Details Handling References for anti-NTRK3 antibody (ABIN2784511) Images back to top
Antigen
Alternative Name NTRK3 (NTRK3 Antibody Abstract)
Background NTRK3 is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.
Alias Symbols: TRKC, gp145(trkC)
Protein Interaction Partner: TNK2, IRAK3, HSP90AA1, APP, SHC2, KIDINS220, DOK5, RASGRF1, MAPK3, DYNLL1, SQSTM1, SHC1, NGFRAP1, IRAK1, HTR2A, MAPK1, PTPN1, PLCG1, JUN, NTF3, NGFR, FRS2,
Protein Size: 825
Molecular Weight 89 kDa
Gene ID 4916
NCBI Accession NM_002530, NP_002521
Pathways RTK Signaling, Neurotrophin Signaling Pathway, Regulation of Cell Size

Application Details

Product Details anti-NTRK3 Antibody Target Details NTRK3 Handling References for anti-NTRK3 antibody (ABIN2784511) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 825 AA

Restrictions For Research Use only

Handling

Product Details anti-NTRK3 Antibody Target Details NTRK3 Application Details References for anti-NTRK3 antibody (ABIN2784511) Images back to top
Format Liquid
Concentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-NTRK3 antibody (ABIN2784511)

Product Details anti-NTRK3 Antibody Target Details NTRK3 Application Details Handling Images back to top
Background publications

Verma, Holmans, Knowles, Grover, Evgrafov, Crowe, Scheftner, Weissman, DePaulo, Potash, Levinson: "Linkage disequilibrium mapping of a chromosome 15q25-26 major depression linkage region and sequencing of NTRK3." in: Biological psychiatry, Vol. 63, Issue 12, pp. 1185-9, 2008

Images

Product Details anti-NTRK3 Antibody Target Details NTRK3 Application Details Handling References for anti-NTRK3 antibody (ABIN2784511) back to top
Supplier Images
Western Blotting (WB) image for anti-Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) (C-Term) antibody (ABIN2784511) WB Suggested Anti-NTRK3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Western Blotting (WB) image for anti-Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) (C-Term) antibody (ABIN2784511) Host: Rabbit
Target Name: NTRK3
Sample Tissue: Human Fetal Muscle
Western Blotting (WB) image for anti-Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) (C-Term) antibody (ABIN2784511) Host: Rabbit
Target Name: NTRK3
Sample Tissue: Human 293T
Antibo...