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anti-Human NTRK3 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended NTRK3 Antibody (supplied by: Log in to see )

Antigen
Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) Antibodies
  • AW125844
  • gp145(trkC)
  • Ntrk3_tv3
  • trkC
  • TrkC
  • TRKC
Epitope
N-Term
43
15
14
12
8
6
6
6
5
4
4
4
3
3
3
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
128
57
37
4
2
2
1
1
1
1
Host
Rabbit
104
40
10
6
2
Clonality
Polyclonal
Conjugate
This NTRK3 antibody is un-conjugated
7
4
4
4
4
4
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
130
78
70
14
8
5
1
Supplier
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Catalog No. ABIN359954
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008987243 ABIN372493 IHC (p) WB Goat IgG AA 1-429, Extracellular Domain, N-Term Log in to see Polyclonal
0.0008987243 ABIN392066 IHC (p) WB Rabbit Ig AA 31-61, N-Term Log in to see Polyclonal
0.0008987243 ABIN409292 ICC IF IHC (p) IHC Rabbit AA 50-150, Extracellular Domain Log in to see Polyclonal
0.0008987243 ABIN1499842 ICC IF IHC (p) WB Mouse IgG1 Log in to see 24B3
0.0008987243 ABIN1499841 IF IHC (p) WB Mouse IgG1 Log in to see 4E10
0.0008987243 ABIN315971 IHC (p) IHC WB Rabbit Log in to see Polyclonal
0.0008987243 ABIN1109344 IHC (p) WB Mouse IgG1 Log in to see 7H6
0.0008987243 ABIN1737564 IHC (p) WB Goat IgG Extracellular Domain, AA 1-429 Log in to see Polyclonal
0.0008987243 ABIN316024 IHC (fro) IHC (p) IHC WB Rabbit IgG Log in to see Polyclonal
0.0008987243 ABIN1918828 IHC (p) WB Rabbit N-Term, AA 31-61 Log in to see Polyclonal
0.0008987243 ABIN3028867 IHC (p) WB Rabbit IgG AA 167-182 Log in to see Polyclonal
0.0008987243 ABIN2963644 IHC (p) WB Rabbit AA 31-61, N-Term Log in to see Polyclonal
0.0008987243 ABIN2214601 IHC (p) ELISA Rabbit Log in to see

Similar anti-NTRK3 Antibodies

Application / Reactivity Human
ELISA 51 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
Flow Cytometry (FACS) 5 Antibodies
Immunocytochemistry (ICC) 2 Antibodies
Immunofluorescence (IF) 9 Antibodies
Immunohistochemistry (IHC) 64 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 14 Antibodies
Western Blotting (WB) 105 Antibodies

General

Antigen Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) Antibodies
Epitope N-Term
(43), (15), (14), (12), (8), (6), (6), (6), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(128), (57), (37), (4), (2), (2), (1), (1), (1), (1)
Host Rabbit
(104), (40), (10), (6), (2)
Clonality
Polyclonal
Conjugate This NTRK3 antibody is un-conjugated
(7), (4), (4), (4), (4), (4)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(130), (78), (70), (14), (8), (5), (1)
Pubmed 2 references available
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Product Details anti-NTRK3 Antibody

Target Details NTRK3 Application Details Handling References for anti-NTRK3 Antibody (ABIN359954) Images
Specificity This antibody reacts to TRKC.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human TRKC.
Isotype Ig

Target Details NTRK3

Product Details anti-NTRK3 Antibody Application Details Handling References for anti-NTRK3 Antibody (ABIN359954) Images back to top
Antigen
Alternative Name TrkC (NTRK3 Antibody Abstract)
Background TRKC, a member of the insuline receptor subfamily of Tyr protein kinases, is a receptor for neurotrophin-3 (NT-3). Known substrates for the TRK receptors are SHC, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. The protein is widely expressed, mainly in the nervous tissue. The isoform B is expressed in a relatively large amount in the adult brain comparatively to fetal brain. TRKC is subject to ligand-mediated auto-phosphorylation. The protein structure contains 2 immunoglobulin-like C2-type domains and 2 leucine-rich (LRR) repeats.Synonyms: GP145-TrkC, NT-3 growth factor receptor, NTRK3, Neurotrophic tyrosine kinase receptor type 3, TrkC tyrosine kinase
Gene ID 4916, 9606
UniProt Q16288
Research Area Cancer
Pathways RTK Signaling, Neurotrophin Signaling Pathway

Application Details

Product Details anti-NTRK3 Antibody Target Details NTRK3 Handling References for anti-NTRK3 Antibody (ABIN359954) Images back to top
Application Notes ELISA: 1/1,000. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-NTRK3 Antibody Target Details NTRK3 Application Details References for anti-NTRK3 Antibody (ABIN359954) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-NTRK3 Antibody (ABIN359954)

Product Details anti-NTRK3 Antibody Target Details NTRK3 Application Details Handling Images back to top
Background publications

McGregor, Baylin, Griffin, Hawkins, Nelkin: "Molecular cloning of the cDNA for human TrkC (NTRK3), chromosomal assignment, and evidence for a splice variant." in: Genomics, Vol. 22, Issue 2, pp. 267-72, 1995

Shelton, Sutherland, Gripp, Camerato, Armanini, Phillips, Carroll, Spencer, Levinson: "Human trks: molecular cloning, tissue distribution, and expression of extracellular domain immunoadhesins." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 15, Issue 1 Pt 2, pp. 477-91, 1995

Images

Product Details anti-NTRK3 Antibody Target Details NTRK3 Application Details Handling References for anti-NTRK3 Antibody (ABIN359954) back to top
Supplier Images
 image for anti-NTRK3 antibody (Neurotrophic tyrosine Kinase, Receptor, Type 3) (N-Term) (ABIN359954) anti-Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) (N-Term) antibody