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Browse our NTRK3 Proteins (NTRK3)

Full name:
Neurotrophic tyrosine Kinase, Receptor, Type 3 Proteins (NTRK3)
On www.antibodies-online.com are 25 Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) Proteins from 9 different suppliers available. Additionally we are shipping NTRK3 Antibodies (197) and NTRK3 Kits (24) and many more products for this protein. A total of 261 NTRK3 products are currently listed.
Synonyms:
AW125844, gp145(trkC), Ntrk3_tv3, trkC
list all proteins Gene Name GeneID UniProt
NTRK3 4916 Q16288
NTRK3 18213 Q6VNS1
Rat NTRK3 NTRK3 29613 Q03351

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NTRK3 Proteins (NTRK3) by Origin

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Top referenced NTRK3 Proteins

  1. Human NTRK3 Protein expressed in Human Cells - ABIN2001965 : Lamballe, Klein, Barbacid: trkC, a new member of the trk family of tyrosine protein kinases, is a receptor for neurotrophin-3. in Cell 1991 (PubMed)
    Show all 5 references for ABIN2001965

  2. Mouse (Murine) NTRK3 Protein expressed in Human Cells - ABIN2007662 : Edsjö, Hallberg, Fagerström, Larsson, Axelson, Påhlman: Differences in early and late responses between neurotrophin-stimulated trkA- and trkC-transfected SH-SY5Y neuroblastoma cells. in Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 2001 (PubMed)
    Show all 5 references for ABIN2007662

More Proteins for NTRK3 Interaction Partners

Human Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) interaction partners

  1. ETV6-NTRK3, MYO5A-NTRK3 and MYH9-NTRK3 fusions are identified in Spitz tumours and demonstrated that NTRK3 fusions constitutively activate the mitogen-activated protein kinase, phosphoinositide 3-kinase and phospholipase Cgamma1 pathways in melanocytes.

  2. A subset of ALK-negative inflammatory myofibroblastic tumour (IMT) have rearrangement of ROS1 (show ROS1 Proteins), ETV6 (show ETV6 Proteins) or NTRK3 as a possible oncogenic mechanism.

  3. TrkC-miR2 as a novel regulator of Wnt (show WNT2 Proteins) signaling, which might be a candidate oncogenic colorectal cancer biomarker.

  4. High expression of TrkA (show NTRK1 Proteins), TrkB (show NTRK2 Proteins), or TrkC was significantly associated with histopathology

  5. Pilot study usee targeted exome sequencing in an attempt to discover novel candidate genes related to Internet Gaming Disorder. Despite a relatively small sample, the targeted exome sequencing was feasible and valuable and revealed that rs2229910 of NTRK3 may be a protective SNP against Internet Gaming Disorder.

  6. Case Report: ETV6 (show ETV6 Proteins)-NTRK3 translocation in primary cutaneous mammary analog secretory carcinoma.

  7. the ETV6-NTRK3 fusion might identify a subset of gastrointestinal stromal tumours with peculiar clinicopathological characteristics

  8. TNS1, MET, and TRKC tyrosine-phosphorylated proteins are upregulated during epithelial-mesenchymal transition induced with TGF-beta (show TGFB1 Proteins), and predict the outcome in lung adenocarcinoma patients.

  9. SNPs in the NTRK3 gene, pain, physical activity, and fear of falling were directly associated with depressive symptoms in older adults.

  10. Molecular analysis of ETV6 (show ETV6 Proteins) gene rearranged mammary analogue secretory carcinoma of salivary glands tumors with lack of classical ETV6-NTRK3 fusion.

Mouse (Murine) Neurotrophic tyrosine Kinase, Receptor, Type 3 (NTRK3) interaction partners

  1. our data suggest that Runx3 (show RUNX3 Proteins) may play a crucial role in the development of DRGs by regulating the expression of Ntrk3 variants

  2. adult homozygous TrkAC knock-in mice displayed severe deficits in acute and tissue injury-induced pain, representing the first viable adult Trk (show NTRK1 Proteins) mouse mutant with a pain phenotype

  3. TrkC expression in E13.5 VCG neurons requires NeuroD (show NEUROD1 Proteins) and that TrkC expression may be necessary for the normal migration and innervations of those neurons.

  4. The dependence receptor TrkC interacts with Cobra1 (show COBRA1 Proteins).TrkC killer fragment shuttles with Cobra1 (show COBRA1 Proteins) to the mitochondria to engage apoptosis.

  5. ETV6 (show ETV6 Proteins)-SAM (show TTN Proteins) domain interface mutations block ETV6 (show ETV6 Proteins)-NTRK3-induced cellular transformation

  6. This study demonistrated that NTRK3 plays a role in panic disorder by regulating hippocampus-dependent fear memories.

  7. Despite elimination of TrkC mRNA, no differences in development of kindling were detected between TrkC conditional null and wild type control mice.

  8. find that both IRS1 (show IRS1 Proteins) and kinase active IGF1R (show IGF1R Proteins) are required for ETV6 (show ETV6 Proteins)-NTRK3 transformation, that tyrosine phosphorylated IRS1 (show IRS1 Proteins) is present in high molecular weight complexes with EN and IGF1R (show IGF1R Proteins), and that EN colocalizes with IGF1R (show IGF1R Proteins) at the plasma membrane

  9. Data describe the distribution and changes of TrkB (show NTRK2 Proteins) and TrkC in the dopamine neurons of the substantia nigra by comparison of control and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP (show PTPN2 Proteins)) Parkinson disease mouse model.

  10. Data suggest that postsynaptic TrkC trans interaction with presynaptic PTPsigma (show PTPRS Proteins) generates bidirectional adhesion and recruitment essential for excitatory synapse development and positions these signaling molecules at the center of synaptic pathways.

NTRK3 Protein Profile

Protein Summary

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with NTRK3

  • neurotrophic tyrosine kinase, receptor, type 3 (NTRK3)
  • neurotrophic tyrosine kinase, receptor, type 3 (LOC100227403)
  • neurotrophic tyrosine kinase, receptor, type 3 (Ntrk3)
  • AW125844 protein
  • gp145(trkC) protein
  • Ntrk3_tv3 protein
  • trkC protein

Protein level used designations for NTRK3

NT-3 growth factor receptor , neurotrophic tyrosine kinase, receptor, type 3 , NT-3 growth factor receptor-like , ETS related protein-neurotrophic receptor tyrosine kinase fusion protein , ETV6-NTRK3 fusion , GP145-TrkC , tyrosine kinase receptor C , neurotrophin-3 , trk-C , trkC tyrosine kinase , neural receptor protein-tyrosine kinase (trkC) , gp145-trkC , neurotrophic tyrosine kinase receptor type 3 , tyrosine kinase C receptor, TrkC receptor, high-affinity neurotrophin receptor

GENE ID SPECIES
697615 Macaca mulatta
100227403 Taeniopygia guttata
100458353 Pongo abelii
4916 Homo sapiens
18213 Mus musculus
29613 Rattus norvegicus
397511 Sus scrofa
609087 Canis lupus familiaris
396081 Gallus gallus
539126 Bos taurus
100731493 Cavia porcellus
101121631 Ovis aries
467751 Pan troglodytes
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