anti-Mouse (Murine) PAK4 antibody for Enzyme Immunoassay

Recommended PAK4 Antibody (supplied by: Log in to see )

Antigen
P21-Activated Kinase 4 (PAK4) Antibodies
  • 5730488L07Rik
  • AW555722
  • mKIAA1142
  • p21 protein (Cdc42/Rac)-activated kinase 4
  • p21-activated kinase 4
  • PAK4
  • LOC100336246
  • Pak4
Epitope
N-Term
28
16
15
12
11
6
6
6
5
4
3
3
3
2
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
187
88
73
19
8
7
6
5
3
2
2
2
2
1
1
Host
Rabbit
158
29
2
Clonality
Polyclonal
Conjugate
This PAK4 antibody is un-conjugated
12
11
10
6
6
5
3
3
3
3
3
3
3
3
2
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
142
66
46
34
23
22
14
9
7
1
1
1
1
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Catalog No. ABIN360324
$ 390.50
Plus shipping costs $45.00

General

Antigen P21-Activated Kinase 4 (PAK4) Antibodies
Epitope N-Term
(28), (16), (15), (12), (11), (6), (6), (6), (5), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(187), (88), (73), (19), (8), (7), (6), (5), (3), (2), (2), (2), (2), (1), (1)
Host Rabbit
(158), (29), (2)
Clonality
Polyclonal
Conjugate This PAK4 antibody is un-conjugated
(12), (11), (10), (6), (6), (5), (3), (3), (3), (3), (3), (3), (3), (3), (2), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(142), (66), (46), (34), (23), (22), (14), (9), (7), (1), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-PAK4 Antibody

Target Details PAK4 Application Details Handling ProductDetails: References for anti-PAK4 antibody (ABIN360324) Images
Specificity This antibody reacts to PAK4.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PAK4.
Isotype Ig

Target Details PAK4

Product Details anti-PAK4 Antibody Application Details Handling ProductDetails: References for anti-PAK4 antibody (ABIN360324) Images back to top
Antigen
Alternative Name PAK4 (PAK4 Antibody Abstract)
Background PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3, PAK4, PAK5, and PAK6. PAK proteins serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton.Synonyms: KIAA1142, PAK 4, PAK-4, Serine/threonine-protein kinase PAK 4, p21-activated kinase 4
Gene ID 10298, 9606
UniProt O96013
Research Area Cancer, Cell Cycle, Cytoskeleton, Microfilaments, Apoptosis/Necrosis, Kinases/Phosphatases
Pathways RTK Signaling

Application Details

Product Details anti-PAK4 Antibody Target Details PAK4 Handling ProductDetails: References for anti-PAK4 antibody (ABIN360324) Images back to top
Application Notes ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-PAK4 Antibody Target Details PAK4 Application Details ProductDetails: References for anti-PAK4 antibody (ABIN360324) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

ProductDetails: References for anti-PAK4 antibody (ABIN360324)

Product Details anti-PAK4 Antibody Target Details PAK4 Application Details Handling Images back to top
Background publications

Lu, Pan, Devaux, Ray: "p21-activated protein kinase 4 (PAK4) interacts with the keratinocyte growth factor receptor and participates in keratinocyte growth factor-mediated inhibition of oxidant-induced cell death." in: The Journal of biological chemistry, Vol. 278, Issue 12, pp. 10374-80, 2003

Bagrodia, Cerione: "Pak to the future." in: Trends in cell biology, Vol. 9, Issue 9, pp. 350-5, 1999

Images

Product Details anti-PAK4 Antibody Target Details PAK4 Application Details Handling ProductDetails: References for anti-PAK4 antibody (ABIN360324) back to top
Supplier Images
 image for anti-P21-Activated Kinase 4 (PAK4) (N-Term) antibody (ABIN360324) anti-P21-Activated Kinase 4 (PAK4) (N-Term) antibody
 image for anti-P21-Activated Kinase 4 (PAK4) (N-Term) antibody (ABIN360324) anti-P21-Activated Kinase 4 (PAK4) (N-Term) antibody (Image 2)