Browse our anti-PDGFA (PDGFA) Antibodies

Full name:
anti-Platelet-Derived Growth Factor alpha Polypeptide Antibodies (PDGFA)
On are 92 Platelet-Derived Growth Factor alpha Polypeptide (PDGFA) Antibodies from 20 different suppliers available. Additionally we are shipping PDGFA Kits (53) and PDGFA Proteins (42) and many more products for this protein. A total of 197 PDGFA products are currently listed.
pdgf, PDGF-A, PDGF1, pdgfa, pdgfa-2, PDGFACP, zgc:100777
list all antibodies Gene Name GeneID UniProt
PDGFA 18590 P20033
PDGFA 5154 P04085
PDGFA 25266 P28576

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Most Popular Reactivities for anti-PDGFA (PDGFA) Antibodies

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anti-Mouse (Murine) PDGFA Antibodies:

anti-Human PDGFA Antibodies:

anti-Rat (Rattus) PDGFA Antibodies:

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Top referenced anti-PDGFA Antibodies

  1. Human Polyclonal PDGFA Primary Antibody for Func, IHC (p) - ABIN2476090 : Rorsman, Bywater, Knott, Scott, Betsholtz: Structural characterization of the human platelet-derived growth factor A-chain cDNA and gene: alternative exon usage predicts two different precursor proteins. in Molecular and cellular biology 1988 (PubMed)
    Show all 2 references for 2476090

  2. Human Polyclonal PDGFA Primary Antibody for IHC (p), IHC - ABIN446973 : Wehler, Hamdi, Maderer, Graf, Gockel, Schmidtmann, Hainz, Berger, Theobald, Galle, Moehler, Schimanski: Single-agent therapy with sorafenib or 5-FU is equally effective in human colorectal cancer xenograft--no benefit of combination therapy. in International journal of colorectal disease 2013 (PubMed)
    Show all 2 references for 446973

  3. Human Polyclonal PDGFA Primary Antibody for IF (p), IHC (p) - ABIN726155 : Lee, Zheng, Kang, Kim, Oh, Cho: Therapeutic efficacy of autologous platelet-rich plasma and polydeoxyribonucleotide on female pattern hair loss. in Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2015 (PubMed)
    Show all 2 references for 726155

  4. Human Polyclonal PDGFA Primary Antibody for IHC (p), WB - ABIN388459 : Müller, Richter, Rinas: Kinetics control preferential heterodimer formation of platelet-derived growth factor from unfolded A- and B-chains. in The Journal of biological chemistry 2003 (PubMed)

More Antibodies against PDGFA Interaction Partners

Zebrafish Platelet-Derived Growth Factor alpha Polypeptide (PDGFA) interaction partners

  1. Zebrafish pdgf-a mRNA was present at high levels in fertilized eggs as well as in all embryonic cells up to the end of gastrulation

Mouse (Murine) Platelet-Derived Growth Factor alpha Polypeptide (PDGFA) interaction partners

  1. These studies uncover PI3K/AKT2 (show AKT2 Antibodies) as a direct PDGFA target that is activated in adipocyte stem cells.

  2. stronger fibrotic effect generated by Platelet-derived growth factor alpha overexpression was mediated by Platelet-derived growth factor receptor (show PDGFRB Antibodies) alphalpha in cardiac interstitial mesenchymal cells

  3. PDGF-AA impairs endothelium-dependent vasodilation and PDGF-AA mediates BMP4 (show BMP4 Antibodies)-induced adverse effect on endothelial cell function through SMAD1 (show SMAD1 Antibodies)/5- and SMAD4 (show SMAD4 Antibodies)-dependent mechanisms.

  4. Both cell proliferation and hair inductive activity in murine DPCs are maintained by the synergistic effect of fibroblast growth factor 2 (show FGF2 Antibodies) and platelet-derived growth factor receptor alpha (show PDGFRA Antibodies).

  5. Primary high invasive Glioma initiating cells SU3 contribute to transformation of adjacent normal host glial cells in local tumor microenvironment possibly via PDGF/PDGFR (show PDGFRB Antibodies) signaling activation.

  6. Silencing the Col4-alpha1 gene or disrupting integrin engagement by blocking the antibody reduced the expression of platelet-derived growth factor A (PDGF-A), a potent chemotactic factor for fibroblasts.

  7. Platelet-derived growth factor mediates interleukin-13 (show IL13 Antibodies)-induced collagen I production in mouse airway fibroblasts.

  8. senescent cells have a role in optimal wound healing through secretion of PDGF-AA

  9. leading to a PDGF-responsive SRF-driven transcriptional program in the midface

  10. Platelet-derived growth factor plays an integral role in mediating TGF-beta1 (show TGFB1 Antibodies)-dependent mesenchymal stem cell stiffening.

Human Platelet-Derived Growth Factor alpha Polypeptide (PDGFA) interaction partners

  1. PDGFAA in tumor drainage and HER2 (show ERBB2 Antibodies) in peripheral vein blood may have roles in synchronous liver metastasis of colorectal cancer

  2. Insulin (show INS Antibodies) treatment caused sustained Akt (show AKT1 Antibodies) activity, whereas EGF (show EGF Antibodies) or PDGF-AA promoted transient signaling; PDGF-BB produced sustained responses at higher concentrations.Transient responses to EGF (show EGF Antibodies) were caused by negative feedback at the receptor level, as a second treatment yielded minimal responses, whereas parallel exposure to IGF-I (show IGF1 Antibodies) caused full Akt (show AKT1 Antibodies) activation

  3. these findings suggest that IGFBP-3 (show IGFBP3 Antibodies) suppresses transcription of EGR1 (show EGR1 Antibodies) and its target genes bFGF (show FGF2 Antibodies) and PDGF through inhibiting IGF-1 (show IGF1 Antibodies)-dependent ERK (show EPHB2 Antibodies) and AKT (show AKT1 Antibodies) activation.

  4. Based on a luciferase reporter assay, plateletderived growth factorA (PDGFA) was identified as a direct target gene of miR375. Additionally, overexpression of PDGFA significantly reversed the effect of miR375 on cell migration and invasion in oral squamous cell carcinoma cell.

  5. The highest PDGF AA levels were found in mothers of fetuses with hypoplastic left heart syndrome . These findings may be useful in screening for congenital heart defects (CCHDs) and offer insight into their association with nuchal translucency

  6. Low concentration of PDGF-AB showed synergism with IFN-alpha (show IFNA Antibodies) in IFN-beta (show IFNB1 Antibodies) and -gamma induction.

  7. downregulated Rab5a (show RAB5A Antibodies) led to slowed cell growth, decreased numbers of migrated cells, decreased numbers of cells at the G0G1 phase and a higher apoptosis rate. However, PDGF significantly rescued these phenomena caused by siRNA against Rab5a (show RAB5A Antibodies)

  8. There are four platelet-derived growth factor (PDGF) genes (PDGFA, PDGFB (show PDGFB Antibodies), PDGFC (show PDGFC Antibodies) and PDGFD (show PDGFD Antibodies)) that reside on chromosomes 7, 22, 4 and 11.

  9. TLR-stimulated pancreatic cancer cells were specifically investigated for activated signaling pathways of VEGF (show VEGFA Antibodies)/PDGF and anti-apoptotic Bcl-xL (show BCL2L1 Antibodies) expression as well as tumor cell growth.

  10. Nox4 (show NOX4 Antibodies) and Duox1/Duox2 (show DUOX1 Antibodies) mediate redox activation of mesenchymal cell migration by PDGF.

Xenopus laevis Platelet-Derived Growth Factor alpha Polypeptide (PDGFA) interaction partners

  1. When PDGF-A signaling is inhibited, prechordal mesoderm cells fail to orient towards the ectoderm, the endogenous source of PDGF-A, and no longer migrate towards it.

PDGFA Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis\; knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene.

Alternative names and synonyms associated with PDGFA

  • platelet-derived growth factor alpha polypeptide (PDGFA) antibody
  • platelet-derived growth factor alpha a (pdgfaa) antibody
  • platelet-derived growth factor alpha polypeptide (pdgfa) antibody
  • collagen alpha-2(I) chain-like (LOC100735371) antibody
  • platelet derived growth factor, alpha (Pdgfa) antibody
  • platelet-derived growth factor alpha polypeptide (Pdgfa) antibody
  • Platelet-derived growth factor subunit A-like (LOC100352388) antibody
  • platelet-derived growth factor subunit A-like (LOC100519764) antibody
  • pdgf antibody
  • PDGF-A antibody
  • PDGF1 antibody
  • pdgfa antibody
  • pdgfa-2 antibody
  • PDGFACP antibody
  • zgc:100777 antibody

Protein level used designations for PDGFA

platelet-derived growth factor subunit A , platelet-derived growth factor alpha polypeptide , PDGF subunit A , PDGF-1 , platelet-derived growth factor A chain , PDGF A-chain , platelet-derived growth factor alpha chain , platelet-derived growth factor alpha isoform 2 preproprotein , Platelet-derived growth factor A chain , platelet derived growth factor, alpha , PDGF-A (S1) , platelet-derived growth factor A chain long form , platelet-derived growth factor A chain short form type 1 , platelet-derived growth factor A chain short form type 2 , platelet-derived growth factor A-chain , platelet-derived growth factor A chain, long form

491597 Canis lupus familiaris
378480 Danio rerio
100038202 Xenopus (Silurana) tropicalis
100735371 Cavia porcellus
18590 Mus musculus
5154 Homo sapiens
25266 Rattus norvegicus
505908 Bos taurus
374196 Gallus gallus
397765 Xenopus laevis
100352388 Oryctolagus cuniculus
100519764 Sus scrofa
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