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anti-Mouse (Murine) PDGFA antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended PDGFA Antibody (supplied by: Log in to see )

Antigen
Platelet-Derived Growth Factor alpha Polypeptide (PDGFA) Antibodies
  • pdgf
  • PDGF-A
  • pdgf-a
  • PDGF1
  • pdgf1
  • pdgfa
  • pdgfa-2
  • PDGFACP
  • zgc:100777
Reactivity
Human, Mouse (Murine), Rat (Rattus)
88
37
36
2
1
1
1
Host
Rabbit
78
6
5
3
Clonality
Polyclonal
Conjugate
This PDGFA antibody is un-conjugated
7
5
4
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
65
35
31
22
16
6
4
4
3
2
2
2
2
1
1
Supplier
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Catalog No. ABIN498533
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089791435 ABIN726155 IF (p) IHC (p) WB Rabbit IgG AA 130-180 Log in to see Polyclonal 1
0.00089791435 ABIN726157 IHC (p) WB Biotin Rabbit IgG AA 130-180 Log in to see Polyclonal
0.00089791435 ABIN726164 IHC (p) WB HRP Rabbit IgG AA 130-180 Log in to see Polyclonal
0.00089791435 ABIN446973 IHC (p) IHC WB Rabbit Lys154 Log in to see Polyclonal
0.00089791435 ABIN1406366 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
0.00089791435 ABIN1388473 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
0.00089791435 ABIN1872577 ICC IHC (fro) IHC (p) ELISA WB Rabbit IgG Log in to see Polyclonal
0.00089791435 ABIN1387831 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-PDGFA antibody for Immunohistochemistry (Paraffin-embedded Sections)

Similar anti-PDGFA Antibodies

Application / Reactivity Human Rat (Rattus) Mouse (Murine)
Western Blotting (WB) 65 Antibodies 15 Antibodies 16 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Neutralization (Neut) 2 Antibodies
Immunoprecipitation (IP) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 18 Antibodies 9 Antibodies 8 Antibodies
Immunohistochemistry (IHC) 31 Antibodies 9 Antibodies 9 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 1 Antibodies 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 22 Antibodies 22 Antibodies 22 Antibodies
Immunofluorescence (IF) 1 Antibodies

General

Antigen Platelet-Derived Growth Factor alpha Polypeptide (PDGFA) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(88), (37), (36), (2), (1), (1), (1)
Host Rabbit
(78), (6), (5), (3)
Clonality
Polyclonal
Conjugate This PDGFA antibody is un-conjugated
(7), (5), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(65), (35), (31), (22), (16), (6), (4), (4), (3), (2), (2), (2), (2), (1), (1)
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Product Details anti-PDGFA Antibody

Target Details PDGFA Application Details Handling Images
Specificity This detects endogenous levels of PDGF-A protein. (region surrounding Lys154)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity chromatography using epitope-specific immunogen
Purity > 95 % (by SDS-PAGE)

Target Details PDGFA

Product Details anti-PDGFA Antibody Application Details Handling Images back to top
Antigen
Alternative Name PDGFA (PDGFA Antibody Abstract)
Background PDGF is a mitogen for mesenchyme- and glia-derived cells. It consists of two disulfide-bonded polypeptide chains, A and B, and occurs as three isoforms, PDGF-AA, PDGF-AB and PDGF-BB. The three isoforms bind with different affinities to two receptor types, α and β, which are structurally related and endowed with protein-tyrosine kinase domains. Ligand binding induces activation of the receptor kinases by formation of receptor dimers, the A subunit of PDGF binds only to α receptors with high affinity, whereas the B subunit can bind to both α and β receptors. Evidence suggests that PDGF may function as a neurotrophic factor. The fact that receptors for PDGF-A are expressed in oligodendrocyte progenitor cells whereas receptors for PDGF-B are expressed on neurons suggests that the different isoforms of PDGF may regulate growth and differentiation of different cell types in the developing central nervous system by paracrine and autocrine routes.Synonyms: PDGF A, PDGF alpha, PDGF subunit A, PDGF-1, PDGF-A, PDGF1, Platelet-derived growth factor A chain, Platelet-derived growth factor alpha, Platelet-derived growth factor subunit A
Molecular Weight approx. 21 kDa
Gene ID 5154
NCBI Accession NP_002598
UniProt P04085
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-PDGFA Antibody Target Details PDGFA Handling Images back to top
Application Notes Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-PDGFA Antibody Target Details PDGFA Application Details Images back to top
Concentration 1.0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-PDGFA Antibody Target Details PDGFA Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-PDGFA antibody (Platelet-Derived Growth Factor alpha Polypeptide) (ABIN498533) Immunohistochemistry analyzes of PDGF-A antibody in paraffin-embedded human lu...
Western Blotting (WB) image for anti-PDGFA antibody (Platelet-Derived Growth Factor alpha Polypeptide) (ABIN498533) Western blot analysis of PDGF-A antibody in extracts from Jurkat cells.