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Browse our PDGFA Proteins (PDGFA)

Full name:
Platelet-Derived Growth Factor alpha Polypeptide Proteins (PDGFA)
On www.antibodies-online.com are 31 Platelet-Derived Growth Factor alpha Polypeptide (PDGFA) Proteins from 11 different suppliers available. Additionally we are shipping PDGFA Antibodies (93) and PDGFA Kits (53) and many more products for this protein. A total of 187 PDGFA products are currently listed.
Synonyms:
pdgf, PDGF-A, PDGF1, pdgfa, pdgfa-2, PDGFACP, zgc:100777
list all proteins Gene Name GeneID UniProt
PDGFA 18590 P20033
PDGFA 5154 P04085
PDGFA 25266 P28576

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PDGFA Proteins (PDGFA) by Origin

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Top referenced PDGFA Proteins

  1. Human PDGFA Protein expressed in Wheat germ - ABIN1314496 : Paule, Nebl, Webb, Vollenhoven, Rombauts, Nie: Proprotein convertase 5/6 cleaves platelet-derived growth factor A in the human endometrium in preparation for embryo implantation. in Molecular human reproduction 2015 (PubMed)

More Proteins for PDGFA Interaction Partners

Zebrafish Platelet-Derived Growth Factor alpha Polypeptide (PDGFA) interaction partners

  1. Zebrafish pdgf-a mRNA was present at high levels in fertilized eggs as well as in all embryonic cells up to the end of gastrulation

Mouse (Murine) Platelet-Derived Growth Factor alpha Polypeptide (PDGFA) interaction partners

  1. PDGF-AA impairs endothelium-dependent vasodilation and PDGF-AA mediates BMP4 (show BMP4 Proteins)-induced adverse effect on endothelial cell function through SMAD1 (show SMAD1 Proteins)/5- and SMAD4 (show SMAD4 Proteins)-dependent mechanisms.

  2. Both cell proliferation and hair inductive activity in murine DPCs are maintained by the synergistic effect of fibroblast growth factor 2 (show FGF2 Proteins) and platelet-derived growth factor receptor alpha (show PDGFRA Proteins).

  3. Primary high invasive Glioma initiating cells SU3 contribute to transformation of adjacent normal host glial cells in local tumor microenvironment possibly via PDGF/PDGFR (show PDGFRB Proteins) signaling activation.

  4. Silencing the Col4-alpha1 gene or disrupting integrin engagement by blocking the antibody reduced the expression of platelet-derived growth factor A (PDGF-A), a potent chemotactic factor for fibroblasts.

  5. Platelet-derived growth factor mediates interleukin-13 (show IL13 Proteins)-induced collagen I production in mouse airway fibroblasts.

  6. senescent cells have a role in optimal wound healing through secretion of PDGF-AA

  7. leading to a PDGF-responsive SRF-driven transcriptional program in the midface

  8. Platelet-derived growth factor plays an integral role in mediating TGF-beta1 (show TGFB1 Proteins)-dependent mesenchymal stem cell stiffening.

  9. GPIbalpha blockade reverses production of interleukin (IL)-1alpha by microglia in response to cerebral ischemia in animals with Streptococcus pneumoniae infection.

  10. these data uncover an early role of PDGF signaling in primitive endoderm cell survival.

Human Platelet-Derived Growth Factor alpha Polypeptide (PDGFA) interaction partners

  1. These findings implicate DNA hypomethylation as a specific factor in mediating overexpression of genes associated with Biliary Atresia (BA) and identify PDGFA as a new candidate in BA pathogenesis.

  2. Human uPAR (show PLAUR Proteins) activation and its association with beta1-integrin are required for PDGF-AB-induced migration.

  3. PDGF-AA impairs endothelium-dependent vasodilation and PDGF-AA mediates BMP4 (show BMP4 Proteins)-induced adverse effect on endothelial cell function through SMAD1 (show GARS Proteins)/5- and SMAD4 (show SMAD4 Proteins)-dependent mechanisms.

  4. The development and severity of age-related cataracts was related to the secretion and expression of PDGF-alpha.

  5. PDGF and TGFbeta1 (show TGFB1 Proteins) regulate acute respiratory distress syndrome-associated lung fibrosis through distinct signaling pathway-mediated activation of fibrosis-related proteins.

  6. Demonstrate a novel positive regulatory feedback loop between FoxM1 (show FOXM1 Proteins) and the PDGF-A/AKT (show AKT1 Proteins) signaling pathway, which contributes to breast cancer cell growth and tumorigenesis.

  7. There was evidence for the involvement of PDGF, IGF-1 (show IGF1 Proteins), and EGF (show EGF Proteins) in primary pulmonary hypoplasia. PDGF deficiency plays a certain role in secondary pulmonary hypoplasia

  8. MIC-1 (show C18orf8 Proteins) and PDGF-A expression is elevated in both prostate tumors and structurally intact adjacent tissues.

  9. Proprotein convertase 5 (show PCSK5 Proteins)/6 cleaves PDGFA in the human endometrium in preparation for embryo implantation.

  10. review elucidates the role of tumor stroma interactions, the roles of PDGF receptor signaling in cancer-associated fibroblasts via alteration of stromal matrix composition and the mitogenic effects of cancer-derived PDGFs.

Xenopus laevis Platelet-Derived Growth Factor alpha Polypeptide (PDGFA) interaction partners

  1. When PDGF-A signaling is inhibited, prechordal mesoderm cells fail to orient towards the ectoderm, the endogenous source of PDGF-A, and no longer migrate towards it.

PDGFA Protein Profile

Protein Summary

The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis\; knockout mice die either as embryos or shortly after birth. Two splice variants have been identified for this gene.

Alternative names and synonyms associated with PDGFA

  • platelet-derived growth factor alpha polypeptide (PDGFA)
  • platelet-derived growth factor alpha a (pdgfaa)
  • platelet-derived growth factor alpha polypeptide (pdgfa)
  • collagen alpha-2(I) chain-like (LOC100735371)
  • platelet derived growth factor, alpha (Pdgfa)
  • platelet-derived growth factor alpha polypeptide (Pdgfa)
  • Platelet-derived growth factor subunit A-like (LOC100352388)
  • platelet-derived growth factor subunit A-like (LOC100519764)
  • pdgf protein
  • PDGF-A protein
  • PDGF1 protein
  • pdgfa protein
  • pdgfa-2 protein
  • PDGFACP protein
  • zgc:100777 protein

Protein level used designations for PDGFA

platelet-derived growth factor subunit A , platelet-derived growth factor alpha polypeptide , PDGF subunit A , PDGF-1 , platelet-derived growth factor A chain , PDGF A-chain , platelet-derived growth factor alpha chain , platelet-derived growth factor alpha isoform 2 preproprotein , Platelet-derived growth factor A chain , platelet derived growth factor, alpha , PDGF-A (S1) , platelet-derived growth factor A chain long form , platelet-derived growth factor A chain short form type 1 , platelet-derived growth factor A chain short form type 2 , platelet-derived growth factor A-chain , platelet-derived growth factor A chain, long form

GENE ID SPECIES
491597 Canis lupus familiaris
378480 Danio rerio
100038202 Xenopus (Silurana) tropicalis
100735371 Cavia porcellus
18590 Mus musculus
5154 Homo sapiens
25266 Rattus norvegicus
505908 Bos taurus
374196 Gallus gallus
397765 Xenopus laevis
100352388 Oryctolagus cuniculus
100519764 Sus scrofa
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