anti-Human PDGFB antibody for Immunofluorescence

Recommended PDGFB Antibody (supplied by: Log in to see )

Antigen
Platelet-Derived Growth Factor beta Polypeptide (PDGFB) Antibodies
  • PDGF-B
  • Sis
  • PDGF-2
  • PDGF2
  • SIS
  • SSV
  • c-sis
  • platelet-derived growth factor beta polypeptide
  • platelet derived growth factor, B polypeptide
  • PDGFB
  • Pdgfb
Epitope
AA 212-241, C-Term
19
15
7
7
6
2
2
2
1
1
1
1
1
1
Reactivity
Human
104
46
45
3
3
3
1
Host
Rabbit
80
22
5
3
Clonality
Polyclonal
Conjugate
This PDGFB antibody is un-conjugated
6
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
83
43
32
27
16
13
6
5
3
2
2
2
2
1
1
1
1
Options
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Catalog No. ABIN388460
$ 324.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN2332336 IF ELISA WB Rabbit IgG AA 212-241, C-Term Log in to see Polyclonal
1 ABIN5585406 ELISA IF WB Rabbit IgG Log in to see Polyclonal
1 ABIN2861211 IF ELISA WB Rabbit C-Term Log in to see Polyclonal
1 ABIN1175868 ICC IF IHC WB FITC Rabbit IgG Log in to see Polyclonal
1 ABIN3222720 IF IHC WB Rabbit IgG Log in to see Polyclonal

Top referenced anti-PDGFB antibody for Immunofluorescence

Similar anti-PDGFB Antibodies

Application / Reactivity Human
Cytometry by Time of Flight (CyTOF) 1 Antibodies
Dot Blot (DB) 1 Antibodies
ELISA 25 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies
Flow Cytometry (FACS) 16 Antibodies
Functional Studies (Func) 2 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 2 Antibodies
Immunofluorescence (IF) 6 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 40 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 2 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 32 Antibodies
Immunoprecipitation (IP) 1 Antibodies
Western Blotting (WB) 78 Antibodies

General

Antigen Platelet-Derived Growth Factor beta Polypeptide (PDGFB) Antibodies
Epitope AA 212-241, C-Term
(19), (15), (7), (7), (6), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(104), (46), (45), (3), (3), (3), (1)
Host Rabbit
(80), (22), (5), (3)
Clonality (Clone)
Polyclonal   ( )
Conjugate This PDGFB antibody is un-conjugated
(6), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (IF), Western Blotting (WB)
(83), (43), (32), (27), (16), (13), (6), (5), (3), (2), (2), (2), (2), (1), (1), (1), (1)
Pubmed 4 references available
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Product Details anti-PDGFB Antibody

Target Details PDGFB Application Details Handling ProductDetails: References for anti-PDGFB antibody (ABIN388460) Images
Specificity This PDGFB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human PDGFB.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen This PDGFB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-241 AA from the C-terminal region of human PDGFB.
Clone RB2203
Isotype Ig

Target Details PDGFB

Product Details anti-PDGFB Antibody Application Details Handling ProductDetails: References for anti-PDGFB antibody (ABIN388460) Images back to top
Antigen
Alternative Name PDGFB (PDGFB Antibody Abstract)
Background PDGFB is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer or as a heterodimer with the platelet-derived growth factor alpha polypeptide, where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor.
Molecular Weight 27283 DA
Gene ID 5155
NCBI Accession NP_148937
Research Area Stem Cells, Cell Signaling, Cancer, Cell Cycle, Cell Structure
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling

Application Details

Product Details anti-PDGFB Antibody Target Details PDGFB Handling ProductDetails: References for anti-PDGFB antibody (ABIN388460) Images back to top
Application Notes WB = 1:1000, IF = 1:10-50
Restrictions For Research Use only

Handling

Product Details anti-PDGFB Antibody Target Details PDGFB Application Details ProductDetails: References for anti-PDGFB antibody (ABIN388460) Images back to top
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months

ProductDetails: References for anti-PDGFB antibody (ABIN388460)

Product Details anti-PDGFB Antibody Target Details PDGFB Application Details Handling Images back to top
Background publications

Müller, Richter, Rinas: "Kinetics control preferential heterodimer formation of platelet-derived growth factor from unfolded A- and B-chains." in: The Journal of biological chemistry, Vol. 278, Issue 20, pp. 18330-5, 2003

Laprise, Grondin, Cayer, McDonald, Dubois et al.: "Furin gene (fur) regulation in differentiating human megakaryoblastic Dami cells: involvement of the proximal GATA recognition motif in the P1 promoter and impact on the maturation of furin ..." in: Blood, Vol. 100, Issue 10, pp. 3578-87, 2002

Maire, Martin, Michalak-Provost, Gattas, Turc-Carel, Lorette, Pedeutour et al.: "Fusion of COL1A1 exon 29 with PDGFB exon 2 in a der(22)t(17;22) in a pediatric giant cell fibroblastoma with a pigmented Bednar tumor component. Evidence for age-related chromosomal pattern in ..." in: Cancer genetics and cytogenetics, Vol. 134, Issue 2, pp. 156-61, 2002

Andrae, Molander, Smits, Funa, Nistér: "Platelet-derived growth factor-B and -C and active alpha-receptors in medulloblastoma cells." in: Biochemical and biophysical research communications, Vol. 296, Issue 3, pp. 604-11, 2002

Images

Product Details anti-PDGFB Antibody Target Details PDGFB Application Details Handling ProductDetails: References for anti-PDGFB antibody (ABIN388460) back to top
Supplier Images
Western Blotting (WB) image for anti-PDGFB antibody (Platelet-Derived Growth Factor beta Polypeptide) (AA 212-241) (ABIN388460) The anti-PDGFC C-term Pab (ABIN388460) is used in Western blot to detect PDGFC in A37...
 image for anti-PDGFB antibody (Platelet-Derived Growth Factor beta Polypeptide) (AA 212-241) (ABIN388460) Confocal immunofluorescent analysis of PDGFB Antibody (C-term) (ABIN388460) with 293 ...